Click here to switch to the map view.

The map label for this gene is aroF [H]

Identifier: 94985921

GI number: 94985921

Start: 1935573

End: 1936640

Strand: Reverse

Name: aroF [H]

Synonym: Dgeo_1821

Alternate gene names: 94985921

Gene position: 1936640-1935573 (Counterclockwise)

Preceding gene: 94985923

Following gene: 94985920

Centisome position: 78.5

GC content: 67.51

Gene sequence:

>1068_bases
ATGACCCAATCTCCCCTACAGGCTGGCCGCACCGAGAACCTGAATGTCACCGCTTTTACGCCGCTGGTCACGCCGCGTGA
ACTGAAGACGGCCCTGCCCCTCACGCCCGCTGCGGAGCGCACCGTGCTTGCCGGAAGAAAGGCTGCCCAGGACATCCTGC
ACGGGCGCGACGCCCGCCTGCTGGTGGTGGTTGGCCCCTGTTCCATCCACGATTTTGAGCAGGCGACCGAATATGCCGCG
CGGCTTGCCCGTCTGCGGGTGCGGGTGCAGAACCGCCTGGAAGTGCAGATGCGGGTGTATGTGGACAAGCCGCGCACGAC
CGTCGGCTGGCGCGGGTACCTGATCGACCCCGATATGACCGGCGCGAATGACATCAACCGGGGCCTGCGTCTGACCCGTG
AGCTGATGCTGCGTGTTTCCGAACTGGGTTTGCCGGTCGCCACCGAGCTGCTCGACCCCTTCGCGCCGCAGTACCTCTTC
GATGCCATGGCCTGGGCCTGCCTGGGGGCCCGCACCACCGAGTCCCAGACCCACCGGGTGATGGCGAGCGCGGTCAGTGC
CCCGATGGGCTTCAAGAATGGCACCGGTGGCGGCCTCAAGCTGGCGGTGGACGCCATCGTCGCTGCCAGTCATCCCCATG
CCTTTTTCACGGTGGACGACGACGGGCGGGCATGTATCGTCCACACCAAGGGGAACCCCGATGGGCACGTGATCCTGCGA
GGTGGGCGACAGGGGCCCAACTACGCGCCTCAATTCGTGCAGGAGGCTGCTGCCCTCATGCAGGCCGCCGGTCTCACCCC
TGCCGTAATGGTGGATTGCTCACACGCCAACAGCGGTTCGGACCATACGCGGCAGGCGCTGGTGTGGCGCGACGTGTCGG
GCCAGCGTCTGGCCGGACAGACGGCCATCAAGGGCCTGATGCTGGAGTCCAACCTGCGCCCCGGCAAGCAGAGCCTGAGC
GCGGGCATCGAGGCCCTGGTGCCCGGCGTGAGCGTGACCGACGCCTGCGTGGGCTGGGACGAGACGGAGGCGCTGCTGCT
GGAAGCCCACGCGGCGTTGGGGGGCTAA

Upstream 100 bases:

>100_bases
TATTGGTTCCGGTCACACCGGGCCTGACGTCTGCGCTGTCCTAGCACGAGTCGCCCGGAGGATCGGTTTCCTCCGGGCCT
TTCCTTTGAGGTGTTGTTCT

Downstream 100 bases:

>100_bases
ACCCTCAACTGCCAGATTTTCTTGATTCGCACGGTCAGCGCGGGCGTGAGGCGGCAGACTAGAGCCATGAATTGGGGTCA
GCAGGACGGAGGCGGCGGGC

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MTQSPLQAGRTENLNVTAFTPLVTPRELKTALPLTPAAERTVLAGRKAAQDILHGRDARLLVVVGPCSIHDFEQATEYAA
RLARLRVRVQNRLEVQMRVYVDKPRTTVGWRGYLIDPDMTGANDINRGLRLTRELMLRVSELGLPVATELLDPFAPQYLF
DAMAWACLGARTTESQTHRVMASAVSAPMGFKNGTGGGLKLAVDAIVAASHPHAFFTVDDDGRACIVHTKGNPDGHVILR
GGRQGPNYAPQFVQEAAALMQAAGLTPAVMVDCSHANSGSDHTRQALVWRDVSGQRLAGQTAIKGLMLESNLRPGKQSLS
AGIEALVPGVSVTDACVGWDETEALLLEAHAALGG

Sequences:

>Translated_355_residues
MTQSPLQAGRTENLNVTAFTPLVTPRELKTALPLTPAAERTVLAGRKAAQDILHGRDARLLVVVGPCSIHDFEQATEYAA
RLARLRVRVQNRLEVQMRVYVDKPRTTVGWRGYLIDPDMTGANDINRGLRLTRELMLRVSELGLPVATELLDPFAPQYLF
DAMAWACLGARTTESQTHRVMASAVSAPMGFKNGTGGGLKLAVDAIVAASHPHAFFTVDDDGRACIVHTKGNPDGHVILR
GGRQGPNYAPQFVQEAAALMQAAGLTPAVMVDCSHANSGSDHTRQALVWRDVSGQRLAGQTAIKGLMLESNLRPGKQSLS
AGIEALVPGVSVTDACVGWDETEALLLEAHAALGG
>Mature_354_residues
TQSPLQAGRTENLNVTAFTPLVTPRELKTALPLTPAAERTVLAGRKAAQDILHGRDARLLVVVGPCSIHDFEQATEYAAR
LARLRVRVQNRLEVQMRVYVDKPRTTVGWRGYLIDPDMTGANDINRGLRLTRELMLRVSELGLPVATELLDPFAPQYLFD
AMAWACLGARTTESQTHRVMASAVSAPMGFKNGTGGGLKLAVDAIVAASHPHAFFTVDDDGRACIVHTKGNPDGHVILRG
GRQGPNYAPQFVQEAAALMQAAGLTPAVMVDCSHANSGSDHTRQALVWRDVSGQRLAGQTAIKGLMLESNLRPGKQSLSA
GIEALVPGVSVTDACVGWDETEALLLEAHAALGG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=350, Percent_Identity=50, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1786969, Length=337, Percent_Identity=50.1483679525223, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI1787996, Length=345, Percent_Identity=46.9565217391304, Blast_Score=321, Evalue=5e-89,
Organism=Saccharomyces cerevisiae, GI6320240, Length=343, Percent_Identity=43.731778425656, Blast_Score=317, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6319726, Length=363, Percent_Identity=45.1790633608815, Blast_Score=317, Evalue=2e-87,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38006; Mature: 37875

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSPLQAGRTENLNVTAFTPLVTPRELKTALPLTPAAERTVLAGRKAAQDILHGRDARL
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
LVVVGPCSIHDFEQATEYAARLARLRVRVQNRLEVQMRVYVDKPRTTVGWRGYLIDPDMT
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCEECEEEEEECCCCC
GANDINRGLRLTRELMLRVSELGLPVATELLDPFAPQYLFDAMAWACLGARTTESQTHRV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
MASAVSAPMGFKNGTGGGLKLAVDAIVAASHPHAFFTVDDDGRACIVHTKGNPDGHVILR
HHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEE
GGRQGPNYAPQFVQEAAALMQAAGLTPAVMVDCSHANSGSDHTRQALVWRDVSGQRLAGQ
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHEEEEECCCCCCHHHH
TAIKGLMLESNLRPGKQSLSAGIEALVPGVSVTDACVGWDETEALLLEAHAALGG
HHHHHHHEECCCCCCHHHHHCCHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQSPLQAGRTENLNVTAFTPLVTPRELKTALPLTPAAERTVLAGRKAAQDILHGRDARL
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEE
LVVVGPCSIHDFEQATEYAARLARLRVRVQNRLEVQMRVYVDKPRTTVGWRGYLIDPDMT
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCEECEEEEEECCCCC
GANDINRGLRLTRELMLRVSELGLPVATELLDPFAPQYLFDAMAWACLGARTTESQTHRV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
MASAVSAPMGFKNGTGGGLKLAVDAIVAASHPHAFFTVDDDGRACIVHTKGNPDGHVILR
HHHHHHCCCCCCCCCCCCCEEEEEHHHCCCCCCEEEEECCCCCEEEEECCCCCCCEEEEE
GGRQGPNYAPQFVQEAAALMQAAGLTPAVMVDCSHANSGSDHTRQALVWRDVSGQRLAGQ
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHEEEEECCCCCCHHHH
TAIKGLMLESNLRPGKQSLSAGIEALVPGVSVTDACVGWDETEALLLEAHAALGG
HHHHHHHEECCCCCCHHHHHCCHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]