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The map label for this gene is uvsE [H]

Identifier: 94985919

GI number: 94985919

Start: 1934355

End: 1935290

Strand: Reverse

Name: uvsE [H]

Synonym: Dgeo_1819

Alternate gene names: 94985919

Gene position: 1935290-1934355 (Counterclockwise)

Preceding gene: 94985920

Following gene: 94985918

Centisome position: 78.44

GC content: 68.16

Gene sequence:

>936_bases
GTGACCTCCTCTCCATCCCCCGCCTATGGCCTGGTGTGCATGACGGCTGGGCCGGAGGTGCGCTTCCGCACGATGACCCT
CTCCCGCTACCGGGTGCTCACCCCAGCTGAACGGGAGGCAAAACTGCTCGACCTCTACGCCGACAACGTGGCGCGGGTGC
AGCGAGCCGCCGCCTTTTGTGCCGCACGCGGTATCCGGCTCTACCGCCTGAGTTCCAGCCTCTTTCCCATGTTCGACCTG
GAGGGGAATGACACGGGCCGGGCCGTGCTCGACCACCTCGCGCCGCAGGTGCAGGCCGCCGGGCAGGCGTTTCGCGACGC
TGGAATCCGCGTGCTGATGCACCCTGAGCAGTTCATCGTCCTGAACTCCGAGCGCCCGGAGGTCCGCACCTCCAGCGCCC
GCACCCTCGCCGCACACGCCGACACGCTCGACCGCTTCGGCTTCGAGCGCTCCACTTGGAATTTGCTGCTGCTGCACGGC
GGCAAGGGGGGGCGGGCAGCTGAACTCGCCGGTATCATTCCCGACCTGCCAGACGCGGTGCGCCTGCGCCTAGGGCTGGA
AAATGACGAACGCGCCTATGGCCCAGCCGAGCTGCTCCCGGTCTGCGAGGGGACCGGCGTGCCGTTCGTGTTCGACGCGC
ACCATCACGTCGTCCGCGAGCGCTTGCCTGACCAGGAAGATCCCAGCGTGCGGGAATGGGTGCTGGCCGCTCGCCGCACC
TGGCAGCCGCCCGAGTGGCAGGTTGTTCATCTCTCCAATGGTCTGGAAGGCCCGCAGGACCGCCGCCACAGCTACCTGAT
TGCGCAGCTTCCTGCCGCCTACTGGGATGTGCCCTGGATCGAGGTGGAAGCGAAGGGCAAGGAGGAGGCGCTGGCGGCTT
TGATGGGTGCCCAGGCGGCGGGCCTGCAGGTGGACGTGGTGGCGGTGGAGGAGTAG

Upstream 100 bases:

>100_bases
GCGGTCTGCCCTTCACCTGGCGCAAGAAGTGGGAGCGCGACTGGGAGAACGTGCGGTACTGCTCCGACCGCTGCCGGGCG
GCGGCGAAACGGGGGAGGAC

Downstream 100 bases:

>100_bases
CTCCGCGCGCCTCCTCCCACGCGCTACCCTGCAGCCGTGAATGTCGTCGTGTTCGACTTGGAAACCACCGGCCTGTCGCC
TGAGCGAGACGCCATCGTGG

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED; Endonuclease beta [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTSSPSPAYGLVCMTAGPEVRFRTMTLSRYRVLTPAEREAKLLDLYADNVARVQRAAAFCAARGIRLYRLSSSLFPMFDL
EGNDTGRAVLDHLAPQVQAAGQAFRDAGIRVLMHPEQFIVLNSERPEVRTSSARTLAAHADTLDRFGFERSTWNLLLLHG
GKGGRAAELAGIIPDLPDAVRLRLGLENDERAYGPAELLPVCEGTGVPFVFDAHHHVVRERLPDQEDPSVREWVLAARRT
WQPPEWQVVHLSNGLEGPQDRRHSYLIAQLPAAYWDVPWIEVEAKGKEEALAALMGAQAAGLQVDVVAVEE

Sequences:

>Translated_311_residues
MTSSPSPAYGLVCMTAGPEVRFRTMTLSRYRVLTPAEREAKLLDLYADNVARVQRAAAFCAARGIRLYRLSSSLFPMFDL
EGNDTGRAVLDHLAPQVQAAGQAFRDAGIRVLMHPEQFIVLNSERPEVRTSSARTLAAHADTLDRFGFERSTWNLLLLHG
GKGGRAAELAGIIPDLPDAVRLRLGLENDERAYGPAELLPVCEGTGVPFVFDAHHHVVRERLPDQEDPSVREWVLAARRT
WQPPEWQVVHLSNGLEGPQDRRHSYLIAQLPAAYWDVPWIEVEAKGKEEALAALMGAQAAGLQVDVVAVEE
>Mature_310_residues
TSSPSPAYGLVCMTAGPEVRFRTMTLSRYRVLTPAEREAKLLDLYADNVARVQRAAAFCAARGIRLYRLSSSLFPMFDLE
GNDTGRAVLDHLAPQVQAAGQAFRDAGIRVLMHPEQFIVLNSERPEVRTSSARTLAAHADTLDRFGFERSTWNLLLLHGG
KGGRAAELAGIIPDLPDAVRLRLGLENDERAYGPAELLPVCEGTGVPFVFDAHHHVVRERLPDQEDPSVREWVLAARRTW
QPPEWQVVHLSNGLEGPQDRRHSYLIAQLPAAYWDVPWIEVEAKGKEEALAALMGAQAAGLQVDVVAVEE

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 34387; Mature: 34256

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSPSPAYGLVCMTAGPEVRFRTMTLSRYRVLTPAEREAKLLDLYADNVARVQRAAAFC
CCCCCCCCEEEEEEECCCCEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AARGIRLYRLSSSLFPMFDLEGNDTGRAVLDHLAPQVQAAGQAFRDAGIRVLMHPEQFIV
HHCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEE
LNSERPEVRTSSARTLAAHADTLDRFGFERSTWNLLLLHGGKGGRAAELAGIIPDLPDAV
ECCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCHH
RLRLGLENDERAYGPAELLPVCEGTGVPFVFDAHHHVVRERLPDQEDPSVREWVLAARRT
EEEECCCCCCCCCCCHHHEEECCCCCCCEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHC
WQPPEWQVVHLSNGLEGPQDRRHSYLIAQLPAAYWDVPWIEVEAKGKEEALAALMGAQAA
CCCCCEEEEECCCCCCCCHHHHHCEEEEECCHHHCCCCEEEEECCCHHHHHHHHHCCCCC
GLQVDVVAVEE
CCEEEEEEECC
>Mature Secondary Structure 
TSSPSPAYGLVCMTAGPEVRFRTMTLSRYRVLTPAEREAKLLDLYADNVARVQRAAAFC
CCCCCCCEEEEEEECCCCEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AARGIRLYRLSSSLFPMFDLEGNDTGRAVLDHLAPQVQAAGQAFRDAGIRVLMHPEQFIV
HHCCEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEE
LNSERPEVRTSSARTLAAHADTLDRFGFERSTWNLLLLHGGKGGRAAELAGIIPDLPDAV
ECCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCHH
RLRLGLENDERAYGPAELLPVCEGTGVPFVFDAHHHVVRERLPDQEDPSVREWVLAARRT
EEEECCCCCCCCCCCHHHEEECCCCCCCEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHC
WQPPEWQVVHLSNGLEGPQDRRHSYLIAQLPAAYWDVPWIEVEAKGKEEALAALMGAQAA
CCCCCEEEEECCCCCCCCHHHHHCEEEEECCHHHCCCCEEEEECCCHHHHHHHHHCCCCC
GLQVDVVAVEE
CCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266; 11807060; 3838572 [H]