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The map label for this gene is coaX

Identifier: 94985849

GI number: 94985849

Start: 1857419

End: 1858219

Strand: Reverse

Name: coaX

Synonym: Dgeo_1749

Alternate gene names: 94985849

Gene position: 1858219-1857419 (Counterclockwise)

Preceding gene: 94985851

Following gene: 94985845

Centisome position: 75.32

GC content: 67.04

Gene sequence:

>801_bases
GTGCCCGCCTCTTTCCCCCTTCTTGCCGTGGACATCGGCAACACCAGCACTGTGCTGGGCCTTGCGGACGAGAGCCTCAG
CCTGACCCACACCTGGCGCATCCGCACCAACCGCGACCTGCTGCCCGATGACCTCGCGCTGCAACTCCACGGCCTCTTCA
CGCTGGCGGGGGCACCCATGCCGCGTGCGGCGGTGTTGAGCAGCGTCGCGCCGCCGCTGGGGGCCAATTACGCGTTCGCC
CTGCGCCGTCATTTCCGAGTTGATGCGTTCGAGGTGGCCGCCGAGAACCTCCCTGACGTCACGGTCGAACTGGACCAGCC
CGGCAGCATCGGCGCGGACCGGCTGTGCAACCTGTTTGGTGCCGAGCGGTACCTGGATGCCTACGAGTACGCCGTCGTCG
TGGATTTCGGCACCTCCACCAACTTCGATGTCATTGCGCGGGGCCGCCGCTTTCTAGGGGGCATTCTCGCCACGGGCGCG
CAGGTCAGCGCTGACGCCCTCTTTGCCCGCGCCGCCAAGCTCCCGCGCATCACGCTCGAAGCGCCCGCTCGCGCCATCGG
CCAGAATACTGTTCACGCCCTGCAATCCGGCCTCGTCTTTGGCTACGCCGAGATGGTAGACGGCCTGCTGCGCCGTGTGC
GCGCCGAACTTCCTGCCCCTGCTGTCGCCATCGCCACCGGTGGCTTTGCCCGCACCATCGAGGGCATCTGCCGCGAGATT
GATTTTTATGACGAAACGCTGACCCTGCGCGGGCTGGTGGAGCTGTGGGCGAGCCGAGAAGCCGTGGGGAAGGGCTTGTA
G

Upstream 100 bases:

>100_bases
CACGGGAAACCTCCAGGGCAAGAGAGAATAGGCTTGTTCTGCACGCTAGCGCGTTCGCGTCTGCCTTGCCAGCGCCTACC
CAAGGCCTACAATTGCCTCC

Downstream 100 bases:

>100_bases
GAAAAAGCGGGTGGGAGACAGCGTATTCGTCTCCCACCCGCTTTTCCTTGATGGCCCAGAGCTGACCCCTCCCTACACCC
CCAGCATCAGGATCAACTTG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPASFPLLAVDIGNTSTVLGLADESLSLTHTWRIRTNRDLLPDDLALQLHGLFTLAGAPMPRAAVLSSVAPPLGANYAFA
LRRHFRVDAFEVAAENLPDVTVELDQPGSIGADRLCNLFGAERYLDAYEYAVVVDFGTSTNFDVIARGRRFLGGILATGA
QVSADALFARAAKLPRITLEAPARAIGQNTVHALQSGLVFGYAEMVDGLLRRVRAELPAPAVAIATGGFARTIEGICREI
DFYDETLTLRGLVELWASREAVGKGL

Sequences:

>Translated_266_residues
MPASFPLLAVDIGNTSTVLGLADESLSLTHTWRIRTNRDLLPDDLALQLHGLFTLAGAPMPRAAVLSSVAPPLGANYAFA
LRRHFRVDAFEVAAENLPDVTVELDQPGSIGADRLCNLFGAERYLDAYEYAVVVDFGTSTNFDVIARGRRFLGGILATGA
QVSADALFARAAKLPRITLEAPARAIGQNTVHALQSGLVFGYAEMVDGLLRRVRAELPAPAVAIATGGFARTIEGICREI
DFYDETLTLRGLVELWASREAVGKGL
>Mature_265_residues
PASFPLLAVDIGNTSTVLGLADESLSLTHTWRIRTNRDLLPDDLALQLHGLFTLAGAPMPRAAVLSSVAPPLGANYAFAL
RRHFRVDAFEVAAENLPDVTVELDQPGSIGADRLCNLFGAERYLDAYEYAVVVDFGTSTNFDVIARGRRFLGGILATGAQ
VSADALFARAAKLPRITLEAPARAIGQNTVHALQSGLVFGYAEMVDGLLRRVRAELPAPAVAIATGGFARTIEGICREID
FYDETLTLRGLVELWASREAVGKGL

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_DEIGD (Q1IXJ0)

Other databases:

- EMBL:   CP000359
- RefSeq:   YP_605213.1
- ProteinModelPortal:   Q1IXJ0
- SMR:   Q1IXJ0
- STRING:   Q1IXJ0
- GeneID:   4057011
- GenomeReviews:   CP000359_GR
- KEGG:   dge:Dgeo_1749
- NMPDR:   fig|68909.1.peg.1836
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   GTACTIF
- ProtClustDB:   PRK13318
- BioCyc:   DGEO319795:DGEO_1749-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28507; Mature: 28376

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: ACT_SITE 113-113 BINDING 138-138 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASFPLLAVDIGNTSTVLGLADESLSLTHTWRIRTNRDLLPDDLALQLHGLFTLAGAPM
CCCCCCEEEEECCCCEEEEEECCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHEECCCCC
PRAAVLSSVAPPLGANYAFALRRHFRVDAFEVAAENLPDVTVELDQPGSIGADRLCNLFG
CHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
AERYLDAYEYAVVVDFGTSTNFDVIARGRRFLGGILATGAQVSADALFARAAKLPRITLE
HHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEC
APARAIGQNTVHALQSGLVFGYAEMVDGLLRRVRAELPAPAVAIATGGFARTIEGICREI
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHC
DFYDETLTLRGLVELWASREAVGKGL
CHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PASFPLLAVDIGNTSTVLGLADESLSLTHTWRIRTNRDLLPDDLALQLHGLFTLAGAPM
CCCCCEEEEECCCCEEEEEECCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHEECCCCC
PRAAVLSSVAPPLGANYAFALRRHFRVDAFEVAAENLPDVTVELDQPGSIGADRLCNLFG
CHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
AERYLDAYEYAVVVDFGTSTNFDVIARGRRFLGGILATGAQVSADALFARAAKLPRITLE
HHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEC
APARAIGQNTVHALQSGLVFGYAEMVDGLLRRVRAELPAPAVAIATGGFARTIEGICREI
CCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHC
DFYDETLTLRGLVELWASREAVGKGL
CHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA