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The map label for this gene is yhdN [H]

Identifier: 94985811

GI number: 94985811

Start: 1818154

End: 1819176

Strand: Reverse

Name: yhdN [H]

Synonym: Dgeo_1711

Alternate gene names: 94985811

Gene position: 1819176-1818154 (Counterclockwise)

Preceding gene: 94985813

Following gene: 94985810

Centisome position: 73.73

GC content: 64.42

Gene sequence:

>1023_bases
ATGGAATACCGCAAGTTGCTCGGCACGGACCTGACCCTGAGTGCGGTCGGCTTCGGTGTCTGGACAGTCGGCACGACCTG
GTGGGGTGTGAAGGACGAGGACATGGCGGTGAGGCTGCTGCGCCGCGCCTTTGACCTGGGCATCACCTTTTTTGACAACG
CGGACACCTACGCCTCGGGTCGCGCGGAAGAGCTCCAGCGCCGTGCCCTGGGCGACGTGCGTGATCAGATTGTGATTGGC
TCCAAGTTTGGCTACGACATCTATAACCACCCCGAACGTCCCGGCCAGCAGGAGCGCCCGCACGATTGGACGCCCGCCTA
CCTCCGCAAGGCGCTCGAGGGCAGCCTCAGGCGTCTGGGCACCGACTACATCGACTATTACCAGCTGCACAACCCGCGGC
TGGACGCCATCCGGAAAGATGACCTGTGGGCCGAGTTGGAGCAGCTCAAGGCGGAGGGTCTGATCCGCGCCTACGGCACC
GCCCTTGGCCCCGCCCTGAACGAACGCCAGATCGAGGAAGGCATCGAGACCATCCGGTTGCGCCGCGCACCCACCCAGAT
TATCTACAACCTGCTGGAGCAGGTGCTCGGCGAACAGATTCTCCCCGTCGCCGAGGAGGAGGGCGTGGGCGTGATGGCCC
GCGTGCCGCATGCTTCTGGGCTGCTGGAAGGGTACATGACCCTCGATACCGAGTTCGAGCCGGGCGACCACCGCAACTGG
CGCCTGACGACCAATGCCCGCCGTAAGGCCTGGATGGAAGACGGCCTGAAAAAGGTTGAACAGCTGCAGGCACAGTTTTT
GGAGGGGCGCACCATCGGTCAGCTCGCGATCCAGTTTGCGCTGCGCTCTCCTGCGATGGCGAGCGTGCTGCCCAACATCT
ACGACGAGAAGGGGCTAGAAGAGTACGCCGCGACCTTCGGCGCCGCGCCCCTGACAGACGCCGAATACGACGCTATCCAG
GTCCTCTACCGCGACAACTTTGGCCTGCCCACCGACCTGCGCGGACAGGAGGTGGCCCGGTGA

Upstream 100 bases:

>100_bases
CCACTCTGCAGCGCCCTCATCGCTGGGCCAGCTGTAGATGTGTTGCCGACCGTTCAGTCGGGGTGAAACGTCCCTCTGCG
CCGGTGGAATAGTGAGGGCT

Downstream 100 bases:

>100_bases
CCGACGAGCCGAAGCCGACGCAGACGGAAAACACGCCGCCCACGGGGGGGAGGCCCGGCGGTGCCCCCGGTGGCCGTCCC
AGGATGATGGTGGACCTCGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MEYRKLLGTDLTLSAVGFGVWTVGTTWWGVKDEDMAVRLLRRAFDLGITFFDNADTYASGRAEELQRRALGDVRDQIVIG
SKFGYDIYNHPERPGQQERPHDWTPAYLRKALEGSLRRLGTDYIDYYQLHNPRLDAIRKDDLWAELEQLKAEGLIRAYGT
ALGPALNERQIEEGIETIRLRRAPTQIIYNLLEQVLGEQILPVAEEEGVGVMARVPHASGLLEGYMTLDTEFEPGDHRNW
RLTTNARRKAWMEDGLKKVEQLQAQFLEGRTIGQLAIQFALRSPAMASVLPNIYDEKGLEEYAATFGAAPLTDAEYDAIQ
VLYRDNFGLPTDLRGQEVAR

Sequences:

>Translated_340_residues
MEYRKLLGTDLTLSAVGFGVWTVGTTWWGVKDEDMAVRLLRRAFDLGITFFDNADTYASGRAEELQRRALGDVRDQIVIG
SKFGYDIYNHPERPGQQERPHDWTPAYLRKALEGSLRRLGTDYIDYYQLHNPRLDAIRKDDLWAELEQLKAEGLIRAYGT
ALGPALNERQIEEGIETIRLRRAPTQIIYNLLEQVLGEQILPVAEEEGVGVMARVPHASGLLEGYMTLDTEFEPGDHRNW
RLTTNARRKAWMEDGLKKVEQLQAQFLEGRTIGQLAIQFALRSPAMASVLPNIYDEKGLEEYAATFGAAPLTDAEYDAIQ
VLYRDNFGLPTDLRGQEVAR
>Mature_340_residues
MEYRKLLGTDLTLSAVGFGVWTVGTTWWGVKDEDMAVRLLRRAFDLGITFFDNADTYASGRAEELQRRALGDVRDQIVIG
SKFGYDIYNHPERPGQQERPHDWTPAYLRKALEGSLRRLGTDYIDYYQLHNPRLDAIRKDDLWAELEQLKAEGLIRAYGT
ALGPALNERQIEEGIETIRLRRAPTQIIYNLLEQVLGEQILPVAEEEGVGVMARVPHASGLLEGYMTLDTEFEPGDHRNW
RLTTNARRKAWMEDGLKKVEQLQAQFLEGRTIGQLAIQFALRSPAMASVLPNIYDEKGLEEYAATFGAAPLTDAEYDAIQ
VLYRDNFGLPTDLRGQEVAR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=306, Percent_Identity=26.797385620915, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI27436964, Length=311, Percent_Identity=26.0450160771704, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4504825, Length=304, Percent_Identity=26.6447368421053, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=26.0450160771704, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=25.7234726688103, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=25.8258258258258, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=29.7546012269939, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=27.3273273273273, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87081735, Length=321, Percent_Identity=26.791277258567, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788081, Length=210, Percent_Identity=31.9047619047619, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI212645785, Length=166, Percent_Identity=30.1204819277108, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24646155, Length=350, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24646159, Length=338, Percent_Identity=26.3313609467456, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38605; Mature: 38605

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRKLLGTDLTLSAVGFGVWTVGTTWWGVKDEDMAVRLLRRAFDLGITFFDNADTYASG
CCCHHHHCCCCCHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
RAEELQRRALGDVRDQIVIGSKFGYDIYNHPERPGQQERPHDWTPAYLRKALEGSLRRLG
CHHHHHHHHHHHHHHHEEECCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
TDYIDYYQLHNPRLDAIRKDDLWAELEQLKAEGLIRAYGTALGPALNERQIEEGIETIRL
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RRAPTQIIYNLLEQVLGEQILPVAEEEGVGVMARVPHASGLLEGYMTLDTEFEPGDHRNW
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHEECCCCCCCCCCCE
RLTTNARRKAWMEDGLKKVEQLQAQFLEGRTIGQLAIQFALRSPAMASVLPNIYDEKGLE
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
EYAATFGAAPLTDAEYDAIQVLYRDNFGLPTDLRGQEVAR
HHHHHHCCCCCCCCCHHHHEEEEECCCCCCCCCCCHHCCC
>Mature Secondary Structure
MEYRKLLGTDLTLSAVGFGVWTVGTTWWGVKDEDMAVRLLRRAFDLGITFFDNADTYASG
CCCHHHHCCCCCHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
RAEELQRRALGDVRDQIVIGSKFGYDIYNHPERPGQQERPHDWTPAYLRKALEGSLRRLG
CHHHHHHHHHHHHHHHEEECCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
TDYIDYYQLHNPRLDAIRKDDLWAELEQLKAEGLIRAYGTALGPALNERQIEEGIETIRL
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RRAPTQIIYNLLEQVLGEQILPVAEEEGVGVMARVPHASGLLEGYMTLDTEFEPGDHRNW
HCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHEECCCCCCCCCCCE
RLTTNARRKAWMEDGLKKVEQLQAQFLEGRTIGQLAIQFALRSPAMASVLPNIYDEKGLE
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHH
EYAATFGAAPLTDAEYDAIQVLYRDNFGLPTDLRGQEVAR
HHHHHHCCCCCCCCCHHHHEEEEECCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]