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The map label for this gene is 94972299

Identifier: 94972299

GI number: 94972299

Start: 188392

End: 189714

Strand: Direct

Name: 94972299

Synonym: Dgeo_2836

Alternate gene names: NA

Gene position: 188392-189714 (Clockwise)

Preceding gene: 94972300

Following gene: 94972298

Centisome position: 32.81

GC content: 63.49

Gene sequence:

>1323_bases
ATGCAGAGAAAAGTTCTTTGTGCAGCTGTTGGCCTGTGCACCGCAGCCCTGATGGTGGGCTGTGGGCAGCAGGCGAGTGC
GCCCCCTCAGGCCCAGGTATACCGGCCAGACTACATCCTGAATGTGCAGCCCCAAGCGGGTGACACGGTGAGCAGTCTCG
AAGCCAGGTACCACGGGCGCGTGATGGCGTTTGATCCCGAAGCCGGCTACGCCATGATCGGGATGGATGCCGCTTCGGCC
AAGAAGTTCAATGCCAGCCGTCTGAGCACCCTTGACCTCTCTTCGGAGGCAGAGCCGAACCTCAATGTGTTCAGTGCCGG
TGGTGGAATGAGCATGTGGGCGGGTGGCGCGATGAGCATGTGGGCCGGCGGTGGAATGAGTATGTGGGCCGGTGGTGGAA
TGAGTATGTGGGCCGGTGGCCAGTATGTCCCCGTTCCCGGGAACACCGCCGCCTTTACCCAGATCAACCTCCAGAACGCC
CAAACACTCGCTCCTAACCTTGGCCAAGGAATCGAGGTCGCCGTCATCGACACCGGCGTCGATCTCTCTCACCCGGCCTT
CACGGGCGCGCTCGATCTCGCCAATGCGAAGGATTACGTCGATGGCGACAGCATCCCGCAGGACGAGGGCACCCCAGGCA
CCGGAGCCTATGGCCACGGCACGGCGGTGGCCAGCATCATTTTGCAAGTCGCCCCCAAAGCCACCATCCTGCCTATTCGG
GTGCTCGGGCCGGACGGCTCGGGTGATGCGGCCAATGTGGCGCTTGCCATTCGCTACGCTGCCGACAAAGGCGCCAAGAT
CATCAACCTCAGCCTAGGCAGTGATGTGCGGGTGGATGCCGTGCAGCAGGCCATCGCCTATGCCGCGGGCCGCAACGTGA
TGGTCGTGTCCTCCGCGGGCAACAGCAACCTGAACAGGTTGACCTATCCGGCGATGGACGCGAGCGGCAAGGGTGTGGTG
GCCGACCACAGCGTCAGCGTCGGCAGCGTGGACGAGACAGACCGCAAGGCCTCCTTCTCCAACTACGCCAAGGAGCTGGA
ACTGGTGGCGCCCGGGGTCAATATCTATGCGGCGGTGCCCGGCAATATGCTCGGCGCCTGGAGCGGAACTTCGATGTCCG
CCCCGCTGGCCGCTGGCAGCCTGGCTCTGGCGGCTGGGCAGCTGGCGACCCTGCCCCCCGATCTGGCGCGCAAGCTCAGG
GACAACGCGGACAATTCCATCTACTCGTCCAACCTCAACACGGATTACGCCGGGATGCTGGGCAAAGGCCGCCTGAACAT
CAGCAAGTTCCTGACCGCGGCCAAAGCAACGGCTTCTCAGTAA

Upstream 100 bases:

>100_bases
GACACCTCAAATGTTAAAAGCTTGTTATAACCAAATGTATAGGATGTGTGGGGGCATCTATCCGCCGAAAAGAGGTGCTG
GTGCCCCCGAAAGGAGCTTC

Downstream 100 bases:

>100_bases
GCCGCCTACGGCCCCAGGCGGAGAAACCTTCACCGGACGGGGAGGCCCGGCCTCTTCCGTCCCTTTCCCGTGTCTTTGTA
AGAAAGTGGGAAGAGGCCGA

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: Ak.1 protease [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQRKVLCAAVGLCTAALMVGCGQQASAPPQAQVYRPDYILNVQPQAGDTVSSLEARYHGRVMAFDPEAGYAMIGMDAASA
KKFNASRLSTLDLSSEAEPNLNVFSAGGGMSMWAGGAMSMWAGGGMSMWAGGGMSMWAGGQYVPVPGNTAAFTQINLQNA
QTLAPNLGQGIEVAVIDTGVDLSHPAFTGALDLANAKDYVDGDSIPQDEGTPGTGAYGHGTAVASIILQVAPKATILPIR
VLGPDGSGDAANVALAIRYAADKGAKIINLSLGSDVRVDAVQQAIAYAAGRNVMVVSSAGNSNLNRLTYPAMDASGKGVV
ADHSVSVGSVDETDRKASFSNYAKELELVAPGVNIYAAVPGNMLGAWSGTSMSAPLAAGSLALAAGQLATLPPDLARKLR
DNADNSIYSSNLNTDYAGMLGKGRLNISKFLTAAKATASQ

Sequences:

>Translated_440_residues
MQRKVLCAAVGLCTAALMVGCGQQASAPPQAQVYRPDYILNVQPQAGDTVSSLEARYHGRVMAFDPEAGYAMIGMDAASA
KKFNASRLSTLDLSSEAEPNLNVFSAGGGMSMWAGGAMSMWAGGGMSMWAGGGMSMWAGGQYVPVPGNTAAFTQINLQNA
QTLAPNLGQGIEVAVIDTGVDLSHPAFTGALDLANAKDYVDGDSIPQDEGTPGTGAYGHGTAVASIILQVAPKATILPIR
VLGPDGSGDAANVALAIRYAADKGAKIINLSLGSDVRVDAVQQAIAYAAGRNVMVVSSAGNSNLNRLTYPAMDASGKGVV
ADHSVSVGSVDETDRKASFSNYAKELELVAPGVNIYAAVPGNMLGAWSGTSMSAPLAAGSLALAAGQLATLPPDLARKLR
DNADNSIYSSNLNTDYAGMLGKGRLNISKFLTAAKATASQ
>Mature_440_residues
MQRKVLCAAVGLCTAALMVGCGQQASAPPQAQVYRPDYILNVQPQAGDTVSSLEARYHGRVMAFDPEAGYAMIGMDAASA
KKFNASRLSTLDLSSEAEPNLNVFSAGGGMSMWAGGAMSMWAGGGMSMWAGGGMSMWAGGQYVPVPGNTAAFTQINLQNA
QTLAPNLGQGIEVAVIDTGVDLSHPAFTGALDLANAKDYVDGDSIPQDEGTPGTGAYGHGTAVASIILQVAPKATILPIR
VLGPDGSGDAANVALAIRYAADKGAKIINLSLGSDVRVDAVQQAIAYAAGRNVMVVSSAGNSNLNRLTYPAMDASGKGVV
ADHSVSVGSVDETDRKASFSNYAKELELVAPGVNIYAAVPGNMLGAWSGTSMSAPLAAGSLALAAGQLATLPPDLARKLR
DNADNSIYSSNLNTDYAGMLGKGRLNISKFLTAAKATASQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319893, Length=235, Percent_Identity=31.4893617021277, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320775, Length=265, Percent_Identity=31.3207547169811, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324576, Length=234, Percent_Identity=30.3418803418803, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 44941; Mature: 44941

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00136 SUBTILASE_ASP ; PS00138 SUBTILASE_SER ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRKVLCAAVGLCTAALMVGCGQQASAPPQAQVYRPDYILNVQPQAGDTVSSLEARYHGR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHCCE
VMAFDPEAGYAMIGMDAASAKKFNASRLSTLDLSSEAEPNLNVFSAGGGMSMWAGGAMSM
EEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHE
WAGGGMSMWAGGGMSMWAGGQYVPVPGNTAAFTQINLQNAQTLAPNLGQGIEVAVIDTGV
CCCCCCEEECCCCEEECCCCEEEECCCCCEEEEEEECCCCHHCCCCCCCCCEEEEEECCC
DLSHPAFTGALDLANAKDYVDGDSIPQDEGTPGTGAYGHGTAVASIILQVAPKATILPIR
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEE
VLGPDGSGDAANVALAIRYAADKGAKIINLSLGSDVRVDAVQQAIAYAAGRNVMVVSSAG
EECCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCC
NSNLNRLTYPAMDASGKGVVADHSVSVGSVDETDRKASFSNYAKELELVAPGVNIYAAVP
CCCCCEEEECCCCCCCCCEEEECCEECCCCCCCHHHHHHHHHHHHEEEECCCCEEEEECC
GNMLGAWSGTSMSAPLAAGSLALAAGQLATLPPDLARKLRDNADNSIYSSNLNTDYAGML
CCEEECCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCHHCCC
GKGRLNISKFLTAAKATASQ
CCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQRKVLCAAVGLCTAALMVGCGQQASAPPQAQVYRPDYILNVQPQAGDTVSSLEARYHGR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHCCE
VMAFDPEAGYAMIGMDAASAKKFNASRLSTLDLSSEAEPNLNVFSAGGGMSMWAGGAMSM
EEEECCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHE
WAGGGMSMWAGGGMSMWAGGQYVPVPGNTAAFTQINLQNAQTLAPNLGQGIEVAVIDTGV
CCCCCCEEECCCCEEECCCCEEEECCCCCEEEEEEECCCCHHCCCCCCCCCEEEEEECCC
DLSHPAFTGALDLANAKDYVDGDSIPQDEGTPGTGAYGHGTAVASIILQVAPKATILPIR
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEE
VLGPDGSGDAANVALAIRYAADKGAKIINLSLGSDVRVDAVQQAIAYAAGRNVMVVSSAG
EECCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCC
NSNLNRLTYPAMDASGKGVVADHSVSVGSVDETDRKASFSNYAKELELVAPGVNIYAAVP
CCCCCEEEECCCCCCCCCEEEECCEECCCCCCCHHHHHHHHHHHHEEEECCCCEEEEECC
GNMLGAWSGTSMSAPLAAGSLALAAGQLATLPPDLARKLRDNADNSIYSSNLNTDYAGML
CCEEECCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCHHCCC
GKGRLNISKFLTAAKATASQ
CCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7993087; 10588904 [H]