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The map label for this gene is arnB [H]

Identifier: 94313511

GI number: 94313511

Start: 1207983

End: 1209158

Strand: Direct

Name: arnB [H]

Synonym: Rmet_4589

Alternate gene names: 94313511

Gene position: 1207983-1209158 (Clockwise)

Preceding gene: 94313510

Following gene: 94313512

Centisome position: 46.82

GC content: 65.31

Gene sequence:

>1176_bases
ATGACTGCTTCCGCTCCGCAGGATTTCCTGCCGTTCGTCCGCCCAAATATTGACGATGCCACCATAGCCGAAGTCGGCAA
GGTGCTGGCATCCGGCTGGATCACGTCCGGACCCAAGGTGCAGGCGTTCGAGGCCACGCTGTCCGATCTGTTCGGCGGCC
GCCCCGTGCGCACGTTCTCCAACGGCTCGGCAACGATGGAAATCGCGCTGCGCATCGCCGACATCGGCCCCGGCGACGAA
GTCATCACCACGCCAATCACCTGGGTCGCCACGGCAAACGTGGTCCTGACGGTTGGCGCCCGTCCGGTCTTCGTCGATAT
CGATCCGCGCACGCGCAATATCGACCTGGATGCCGTAGAAGCCGCCATCACGCCGCGCACGCGAGCCATCATCCCGGTCT
ACCTGTCCGGTCTGCCGGTCGACATGGACCGCCTCTACGCCATCGCGAAGCGCCATAACCTGCGTGTGATCGAAGATGCC
GCGCAGGCTATCGACTCGCGCTGGCGCGGCCAGCGCATCGGCGCATTTGGCGATCTGGTCAGCTTCAGCTTCCAGGCCAA
CAAGAACATCACCACGATCGAGGGCGGCTGCCTCGTCATGAACTCGCCCGAGGAAGCGCAGCGCGCGGAGCGCCTGCGGC
TGCAAGGCGTGATCCGCACCGGCATGGACGGCATGGACGTCGAGGAGCCGGGCGGCAAGTTCAACCTGACCGACGTCAAC
GCTGCCATTGGGCTGGCCCAGCTCCAGCATCTGGACGCGATCACCGCACGCCGCGCCGAACTGGCCGAGACCTATTTCCG
CTGCGCCGCCAACGCCGGACTGGCCGATCTCGGTATCGAACTGCCGCTGCCGCGCGACCCGGACGTGGCTACCACCAACT
GGCACATGTTCCAGGTGGTGCTGCCGACCGACCGCCTGCGTGGCGGCGCCGCGGAAGCGCGCAAGCACGTCATGGAGTCG
ATGCGCGAGTCAGGCATCGGCACTGGCGTGCATTACCCACCGGTTCACCTGTTTACTTACTTCCGCTCCCTGGGCTGGCG
CGAAGGCATGCTGCCGCATGCCGAGCGCATTGGCCGCGGCATCGTCACGCTGCCGATGTTCCCCGCCATGCAGACAGCCG
ACGTGGAGCGGGTTTGCGCAACTCTAAGCGAAACATGCAAACGCCTCTCTCTCTAA

Upstream 100 bases:

>100_bases
CGGCGTGGTGGCTGTTCGGTGAGATGATTGGCCCCTTGCGCGTCGCCGGCATCCTGCTGATACTGGCTGGCGTTTTCCTG
ATTGCCCGCTCCTGACGATC

Downstream 100 bases:

>100_bases
GCTCCGTCGAGGTCTCGGTCGTCATCCCCGTCTACAACGAGGAGGGTGGCCTGCAGGCGCTGTTCGACCGCGTCTATCCG
GCGCTGGACAGCCTGGGCGA

Product: PLP-dependent aminotransferase, UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

Products: NA

Alternate protein names: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-Ara4O aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTASAPQDFLPFVRPNIDDATIAEVGKVLASGWITSGPKVQAFEATLSDLFGGRPVRTFSNGSATMEIALRIADIGPGDE
VITTPITWVATANVVLTVGARPVFVDIDPRTRNIDLDAVEAAITPRTRAIIPVYLSGLPVDMDRLYAIAKRHNLRVIEDA
AQAIDSRWRGQRIGAFGDLVSFSFQANKNITTIEGGCLVMNSPEEAQRAERLRLQGVIRTGMDGMDVEEPGGKFNLTDVN
AAIGLAQLQHLDAITARRAELAETYFRCAANAGLADLGIELPLPRDPDVATTNWHMFQVVLPTDRLRGGAAEARKHVMES
MRESGIGTGVHYPPVHLFTYFRSLGWREGMLPHAERIGRGIVTLPMFPAMQTADVERVCATLSETCKRLSL

Sequences:

>Translated_391_residues
MTASAPQDFLPFVRPNIDDATIAEVGKVLASGWITSGPKVQAFEATLSDLFGGRPVRTFSNGSATMEIALRIADIGPGDE
VITTPITWVATANVVLTVGARPVFVDIDPRTRNIDLDAVEAAITPRTRAIIPVYLSGLPVDMDRLYAIAKRHNLRVIEDA
AQAIDSRWRGQRIGAFGDLVSFSFQANKNITTIEGGCLVMNSPEEAQRAERLRLQGVIRTGMDGMDVEEPGGKFNLTDVN
AAIGLAQLQHLDAITARRAELAETYFRCAANAGLADLGIELPLPRDPDVATTNWHMFQVVLPTDRLRGGAAEARKHVMES
MRESGIGTGVHYPPVHLFTYFRSLGWREGMLPHAERIGRGIVTLPMFPAMQTADVERVCATLSETCKRLSL
>Mature_390_residues
TASAPQDFLPFVRPNIDDATIAEVGKVLASGWITSGPKVQAFEATLSDLFGGRPVRTFSNGSATMEIALRIADIGPGDEV
ITTPITWVATANVVLTVGARPVFVDIDPRTRNIDLDAVEAAITPRTRAIIPVYLSGLPVDMDRLYAIAKRHNLRVIEDAA
QAIDSRWRGQRIGAFGDLVSFSFQANKNITTIEGGCLVMNSPEEAQRAERLRLQGVIRTGMDGMDVEEPGGKFNLTDVNA
AIGLAQLQHLDAITARRAELAETYFRCAANAGLADLGIELPLPRDPDVATTNWHMFQVVLPTDRLRGGAAEARKHVMESM
RESGIGTGVHYPPVHLFTYFRSLGWREGMLPHAERIGRGIVTLPMFPAMQTADVERVCATLSETCKRLSL

Specific function: Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family. ArnB subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=388, Percent_Identity=40.979381443299, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI2367285, Length=380, Percent_Identity=33.1578947368421, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022850
- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: =2.6.1.87 [H]

Molecular weight: Translated: 42586; Mature: 42455

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASAPQDFLPFVRPNIDDATIAEVGKVLASGWITSGPKVQAFEATLSDLFGGRPVRTFS
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEC
NGSATMEIALRIADIGPGDEVITTPITWVATANVVLTVGARPVFVDIDPRTRNIDLDAVE
CCCEEEEEEEEEECCCCCCCEEECCEEEEEECCEEEEECCCEEEEEECCCCCCCCHHHHH
AAITPRTRAIIPVYLSGLPVDMDRLYAIAKRHNLRVIEDAAQAIDSRWRGQRIGAFGDLV
HHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
SFSFQANKNITTIEGGCLVMNSPEEAQRAERLRLQGVIRTGMDGMDVEEPGGKFNLTDVN
EEEEECCCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHH
AAIGLAQLQHLDAITARRAELAETYFRCAANAGLADLGIELPLPRDPDVATTNWHMFQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEECCCCCCCCCCCCCEEEEEEE
LPTDRLRGGAAEARKHVMESMRESGIGTGVHYPPVHLFTYFRSLGWREGMLPHAERIGRG
ECHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCC
IVTLPMFPAMQTADVERVCATLSETCKRLSL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TASAPQDFLPFVRPNIDDATIAEVGKVLASGWITSGPKVQAFEATLSDLFGGRPVRTFS
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEC
NGSATMEIALRIADIGPGDEVITTPITWVATANVVLTVGARPVFVDIDPRTRNIDLDAVE
CCCEEEEEEEEEECCCCCCCEEECCEEEEEECCEEEEECCCEEEEEECCCCCCCCHHHHH
AAITPRTRAIIPVYLSGLPVDMDRLYAIAKRHNLRVIEDAAQAIDSRWRGQRIGAFGDLV
HHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHH
SFSFQANKNITTIEGGCLVMNSPEEAQRAERLRLQGVIRTGMDGMDVEEPGGKFNLTDVN
EEEEECCCCEEEEECCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHH
AAIGLAQLQHLDAITARRAELAETYFRCAANAGLADLGIELPLPRDPDVATTNWHMFQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEECCCCCCCCCCCCCEEEEEEE
LPTDRLRGGAAEARKHVMESMRESGIGTGVHYPPVHLFTYFRSLGWREGMLPHAERIGRG
ECHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCC
IVTLPMFPAMQTADVERVCATLSETCKRLSL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA