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The map label for this gene is 94312735

Identifier: 94312735

GI number: 94312735

Start: 346064

End: 347230

Strand: Direct

Name: 94312735

Synonym: Rmet_3805

Alternate gene names: NA

Gene position: 346064-347230 (Clockwise)

Preceding gene: 94312734

Following gene: 94312736

Centisome position: 13.41

GC content: 65.04

Gene sequence:

>1167_bases
ATGACCATCAATAGCAAGGCATATATCGTCGGGGCGTACGAGCACCCGACCCGCAAGGCACCGGACAAGACCGTTGCCCA
GCTTCACGCGGAAAGCGCCAAGGGCGCGCTCGAGGATGCGGGCCTGTCGCTGGCCGACGTCGACGGCTACTTCTGCGCCG
GTGACGCCCCGGGCCTCGGCATGGTGAACATGGTCGACTATCTCGGCCTGAATGTGCGCCATGTGGATTCGACCGAAATG
GGCGGGTCCTCCTACATCGCCCACGTCTCGCACGCCGCGCAGGCCATCGCTGCCGGCAAGTGCAACGTGGCACTGATCAC
GCTGGCCGGCCGTCCGCGTTCGGAAGGTTCGAGCGGCACGCAGGCACGCAACTGGGGCGCGAACCTGCCGGACCAGCCGT
TCGAGGCACCGTTCAACCCGGTGACGGTCAACCTGTACGCGATGGTTGCCCAGCGGCACATGTACGAGTTCGGCACCACG
CCCGAGCAGCTCGCGTGGGTCAAGGTGGCTGCGTCGCATCACGCCCAGTACAACCCGAACGCCATGTTGCGCGAAGTTGT
CACCGTCGAGGACGTGGTGAATTCCCCGATGATCTCCGACCCGCTGCACCGGCTGGACTGCTGCGTGGTGTCCGATGGTG
GCGGTGCCCTCATCGTGGCCCGCCCGGAAATCGCGGCCAAGCTTAATCGCCCGAAGATCAAGATCCTGGGCGCTGGCGAG
CACGTGAAGGGTTTGCTGGGCGGCCAGGTGGACCTGTCGTGGTCCGCCGCGCGTTTCTCCGGCGCTGCAGCCTTCGAGGA
AGCCCGTGTCACCCCGGCAGACATCAAGTACGCGTCGATCTACGACAGCTTCACGATCACCGTGCTGATGCAGCTGGAAG
ACCTGGGCTTCTGCAAGAAGGGCGAAGGCGGCAAGTTCGTGATGGACGGCAACCTGATCTCCGGCGTGGGCAAGCTGCCG
TTCAATACCGATGGCGGCGGTCTCTGCAATAACCACCCGGCCAACCGTGGCGGCATCACCAAGGTGATCGAAGCCGTGCG
CCAGTTGCGCGGCGAAGCCCACCCCGCGGTGCAGGTGAAGAACTGCGACCTGGCGCTGGCCCAGGGTACCGGCGGCTACA
TGGGCTCACGCCATGGTTCCGCCACGCTGATCCTCGAACGCGAATAA

Upstream 100 bases:

>100_bases
TGACCATGGTAGACGTCCTGCTGGGCGATACCGACCTCCACCTGGAACGCTACGGCGAAGCCATGGCGGCCTGACAAGAC
CCGATAACGGATGACTGTTC

Downstream 100 bases:

>100_bases
CAGGGATGCCACAGATGACGACTCCTTACGTCCCCACTCCGTACAAGGCTCCCGACGAGCAGCCCGACAACACCGCCTTC
TGGCAGGCCGCCCGCGAGGG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTINSKAYIVGAYEHPTRKAPDKTVAQLHAESAKGALEDAGLSLADVDGYFCAGDAPGLGMVNMVDYLGLNVRHVDSTEM
GGSSYIAHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDQPFEAPFNPVTVNLYAMVAQRHMYEFGTT
PEQLAWVKVAASHHAQYNPNAMLREVVTVEDVVNSPMISDPLHRLDCCVVSDGGGALIVARPEIAAKLNRPKIKILGAGE
HVKGLLGGQVDLSWSAARFSGAAAFEEARVTPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVMDGNLISGVGKLP
FNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKNCDLALAQGTGGYMGSRHGSATLILERE

Sequences:

>Translated_388_residues
MTINSKAYIVGAYEHPTRKAPDKTVAQLHAESAKGALEDAGLSLADVDGYFCAGDAPGLGMVNMVDYLGLNVRHVDSTEM
GGSSYIAHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDQPFEAPFNPVTVNLYAMVAQRHMYEFGTT
PEQLAWVKVAASHHAQYNPNAMLREVVTVEDVVNSPMISDPLHRLDCCVVSDGGGALIVARPEIAAKLNRPKIKILGAGE
HVKGLLGGQVDLSWSAARFSGAAAFEEARVTPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVMDGNLISGVGKLP
FNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKNCDLALAQGTGGYMGSRHGSATLILERE
>Mature_387_residues
TINSKAYIVGAYEHPTRKAPDKTVAQLHAESAKGALEDAGLSLADVDGYFCAGDAPGLGMVNMVDYLGLNVRHVDSTEMG
GSSYIAHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGTQARNWGANLPDQPFEAPFNPVTVNLYAMVAQRHMYEFGTTP
EQLAWVKVAASHHAQYNPNAMLREVVTVEDVVNSPMISDPLHRLDCCVVSDGGGALIVARPEIAAKLNRPKIKILGAGEH
VKGLLGGQVDLSWSAARFSGAAAFEEARVTPADIKYASIYDSFTITVLMQLEDLGFCKKGEGGKFVMDGNLISGVGKLPF
NTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVKNCDLALAQGTGGYMGSRHGSATLILERE

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=379, Percent_Identity=26.1213720316623, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI302344762, Length=246, Percent_Identity=28.8617886178862, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI302344760, Length=245, Percent_Identity=29.7959183673469, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI302344767, Length=246, Percent_Identity=28.8617886178862, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI55956775, Length=207, Percent_Identity=28.9855072463768, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537653, Length=389, Percent_Identity=23.9074550128535, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI19921506, Length=399, Percent_Identity=26.3157894736842, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585051, Length=397, Percent_Identity=26.1964735516373, Blast_Score=111, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 41022; Mature: 40891

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINSKAYIVGAYEHPTRKAPDKTVAQLHAESAKGALEDAGLSLADVDGYFCAGDAPGLG
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHCCCEEEECCCEEECCCCCCCC
MVNMVDYLGLNVRHVDSTEMGGSSYIAHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
QARNWGANLPDQPFEAPFNPVTVNLYAMVAQRHMYEFGTTPEQLAWVKVAASHHAQYNPN
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCHHHEEEEEEEHHCCCCCCCC
AMLREVVTVEDVVNSPMISDPLHRLDCCVVSDGGGALIVARPEIAAKLNRPKIKILGAGE
HHHHHHHHHHHHHCCCCCCCCHHHCEEEEEECCCCEEEEECCHHHHHCCCCEEEEEECCH
HVKGLLGGQVDLSWSAARFSGAAAFEEARVTPADIKYASIYDSFTITVLMQLEDLGFCKK
HHHHHCCCEEEEEECHHHHCCCHHHHHCCCCHHHEEEEEECCCEEEEEEEEEHHCCCCCC
GEGGKFVMDGNLISGVGKLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVK
CCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
NCDLALAQGTGGYMGSRHGSATLILERE
CCCEEEECCCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
TINSKAYIVGAYEHPTRKAPDKTVAQLHAESAKGALEDAGLSLADVDGYFCAGDAPGLG
CCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHCCCEEEECCCEEECCCCCCCC
MVNMVDYLGLNVRHVDSTEMGGSSYIAHVSHAAQAIAAGKCNVALITLAGRPRSEGSSGT
HHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
QARNWGANLPDQPFEAPFNPVTVNLYAMVAQRHMYEFGTTPEQLAWVKVAASHHAQYNPN
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCHHHEEEEEEEHHCCCCCCCC
AMLREVVTVEDVVNSPMISDPLHRLDCCVVSDGGGALIVARPEIAAKLNRPKIKILGAGE
HHHHHHHHHHHHHCCCCCCCCHHHCEEEEEECCCCEEEEECCHHHHHCCCCEEEEEECCH
HVKGLLGGQVDLSWSAARFSGAAAFEEARVTPADIKYASIYDSFTITVLMQLEDLGFCKK
HHHHHCCCEEEEEECHHHHCCCHHHHHCCCCHHHEEEEEECCCEEEEEEEEEHHCCCCCC
GEGGKFVMDGNLISGVGKLPFNTDGGGLCNNHPANRGGITKVIEAVRQLRGEAHPAVQVK
CCCCEEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
NCDLALAQGTGGYMGSRHGSATLILERE
CCCEEEECCCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]