Click here to switch to the map view.

The map label for this gene is rnz [H]

Identifier: 94312715

GI number: 94312715

Start: 321465

End: 322646

Strand: Direct

Name: rnz [H]

Synonym: Rmet_3785

Alternate gene names: 94312715

Gene position: 321465-322646 (Clockwise)

Preceding gene: 94312714

Following gene: 94312716

Centisome position: 12.46

GC content: 64.21

Gene sequence:

>1182_bases
ATGCGTGATCTTTTTTCCCGGGCAGGGGCCGGCCCGGTCAATGGCTTCCGCCTGCTTTGTGCGGGGGCATGCGCGGCGCT
CGCCGTCCTGGCTTCAACTTCTCATGCCGATTCGATCGGACAGCCGCACAGTACCTCGGCGGAGCAGTCCGGCGCCAACC
TCGTACTGCTGGGAACGGCCGGCGGCCGGACTTCCTGGCGAGGTTCGCAGTCTGCGGGAATCGCCTCCGCGGTAGTGGTC
AATGGTCAGGTCTACCTTGTCGATTTCGGCGCGGGCTGGCTGCGACGCTACTTCCAGGCGGGCTTGGGCGCGCCGCCACC
AGGACAGGGCCTCGAAACACTACGAGCGGCATTTATCACGCACTTGCACGCAGACCACATCGTGGACTATCCGTCGCTCG
TCCTGTTTGGCGCGTCGGACGGCTTGGCCGAGCGGCGTCAGAAACTCAAGGTGATCGGGCCCGGCTCACGCGGAAAACTC
CCGCCCGCGAGCGGCGGCAACGACGGGGTGGCGGACGTCGTGGCGCCCGAGCAGCCGATGCCTGGCACCGTTGCCATGAC
CGAAGCGCTGTACCGTGCGTTCGCCGCGGACATCAACGACAACATTCTGGATAGCCGCAAGCCGAATCCCCATAGCCGCG
TCGACGTGATGGATATCACGCTGCCTGCAGGCCTTGACGTTGATCCCGATCGCGATCCCGCGCCGCCGATGGCTCCGTTC
GAGATCTACCGTGACGAGAACGTCAGGGTGACGGCAACACTGGTGAACCATGCCCCGGTCTATCCGGCATTCGCGTTTCG
GTTCGACACCTCGACTGGGTCTGTTGTCTTCTCAGGCGATACCAGCCCGGACCGGAATCTGATTCGGTTGGCGCAAGGTG
CCGATGTGCTGGTGCATGAGGTGATCGACACCGCCTGGGTGGATTCCCTGTTCCCGAAGCCCCGGAGCGCGGCACAGGAA
GCCAAGGCGCACCATCTTGTTCATGCGCATACCGCCGCATCGGATGTCGGAGCCGTCGCCGAAGCGGCTCACGTCAAGAC
CCTCGTCCTGTCGCATCTGGCCCCCGCCGACAGTGATCCCCACCGATGGGCAGCAGCCAGCCAAGGCTTTTCGGGGAAGG
TGATCGTTGGTCGCGATCTCCTGTGGATTCCTCTTGTTCCCGCTGCGCCGGAATCGAAATAG

Upstream 100 bases:

>100_bases
TTATCGAGGCCGAGAAGCTCCGTTGGGAGAAGGTGATTTCGGACGCCGGCGTGAAGCCGGAATGATGCCGATCCAGTGCT
GACCTTCCCTTGGAGAACAC

Downstream 100 bases:

>100_bases
CGCACGGGTAGCACCCCCTAGCTTTCCAGATTTTTTCCTATGGCATATGCGCGCCCTCGGCGTGCGGCCTGCGCTCGTCC
CGACGACGAGGCTGAAGATG

Product: zinc phosphodiesterase

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MRDLFSRAGAGPVNGFRLLCAGACAALAVLASTSHADSIGQPHSTSAEQSGANLVLLGTAGGRTSWRGSQSAGIASAVVV
NGQVYLVDFGAGWLRRYFQAGLGAPPPGQGLETLRAAFITHLHADHIVDYPSLVLFGASDGLAERRQKLKVIGPGSRGKL
PPASGGNDGVADVVAPEQPMPGTVAMTEALYRAFAADINDNILDSRKPNPHSRVDVMDITLPAGLDVDPDRDPAPPMAPF
EIYRDENVRVTATLVNHAPVYPAFAFRFDTSTGSVVFSGDTSPDRNLIRLAQGADVLVHEVIDTAWVDSLFPKPRSAAQE
AKAHHLVHAHTAASDVGAVAEAAHVKTLVLSHLAPADSDPHRWAAASQGFSGKVIVGRDLLWIPLVPAAPESK

Sequences:

>Translated_393_residues
MRDLFSRAGAGPVNGFRLLCAGACAALAVLASTSHADSIGQPHSTSAEQSGANLVLLGTAGGRTSWRGSQSAGIASAVVV
NGQVYLVDFGAGWLRRYFQAGLGAPPPGQGLETLRAAFITHLHADHIVDYPSLVLFGASDGLAERRQKLKVIGPGSRGKL
PPASGGNDGVADVVAPEQPMPGTVAMTEALYRAFAADINDNILDSRKPNPHSRVDVMDITLPAGLDVDPDRDPAPPMAPF
EIYRDENVRVTATLVNHAPVYPAFAFRFDTSTGSVVFSGDTSPDRNLIRLAQGADVLVHEVIDTAWVDSLFPKPRSAAQE
AKAHHLVHAHTAASDVGAVAEAAHVKTLVLSHLAPADSDPHRWAAASQGFSGKVIVGRDLLWIPLVPAAPESK
>Mature_393_residues
MRDLFSRAGAGPVNGFRLLCAGACAALAVLASTSHADSIGQPHSTSAEQSGANLVLLGTAGGRTSWRGSQSAGIASAVVV
NGQVYLVDFGAGWLRRYFQAGLGAPPPGQGLETLRAAFITHLHADHIVDYPSLVLFGASDGLAERRQKLKVIGPGSRGKL
PPASGGNDGVADVVAPEQPMPGTVAMTEALYRAFAADINDNILDSRKPNPHSRVDVMDITLPAGLDVDPDRDPAPPMAPF
EIYRDENVRVTATLVNHAPVYPAFAFRFDTSTGSVVFSGDTSPDRNLIRLAQGADVLVHEVIDTAWVDSLFPKPRSAAQE
AKAHHLVHAHTAASDVGAVAEAAHVKTLVLSHLAPADSDPHRWAAASQGFSGKVIVGRDLLWIPLVPAAPESK

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 41196; Mature: 41196

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLFSRAGAGPVNGFRLLCAGACAALAVLASTSHADSIGQPHSTSAEQSGANLVLLGTA
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHCCCCEEEEECC
GGRTSWRGSQSAGIASAVVVNGQVYLVDFGAGWLRRYFQAGLGAPPPGQGLETLRAAFIT
CCCCCCCCCCCCCCEEEEEECCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
HLHADHIVDYPSLVLFGASDGLAERRQKLKVIGPGSRGKLPPASGGNDGVADVVAPEQPM
HHHHHHHCCCCCEEEEECCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCC
PGTVAMTEALYRAFAADINDNILDSRKPNPHSRVDVMDITLPAGLDVDPDRDPAPPMAPF
CCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
EIYRDENVRVTATLVNHAPVYPAFAFRFDTSTGSVVFSGDTSPDRNLIRLAQGADVLVHE
EEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCHHEEHHCCCHHHHHH
VIDTAWVDSLFPKPRSAAQEAKAHHLVHAHTAASDVGAVAEAAHVKTLVLSHLAPADSDP
HHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HRWAAASQGFSGKVIVGRDLLWIPLVPAAPESK
CHHHHHCCCCCCEEEECCCEEEEECCCCCCCCC
>Mature Secondary Structure
MRDLFSRAGAGPVNGFRLLCAGACAALAVLASTSHADSIGQPHSTSAEQSGANLVLLGTA
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHCCCCEEEEECC
GGRTSWRGSQSAGIASAVVVNGQVYLVDFGAGWLRRYFQAGLGAPPPGQGLETLRAAFIT
CCCCCCCCCCCCCCEEEEEECCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
HLHADHIVDYPSLVLFGASDGLAERRQKLKVIGPGSRGKLPPASGGNDGVADVVAPEQPM
HHHHHHHCCCCCEEEEECCCCHHHHHHEEEEECCCCCCCCCCCCCCCCCCEECCCCCCCC
PGTVAMTEALYRAFAADINDNILDSRKPNPHSRVDVMDITLPAGLDVDPDRDPAPPMAPF
CCHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCC
EIYRDENVRVTATLVNHAPVYPAFAFRFDTSTGSVVFSGDTSPDRNLIRLAQGADVLVHE
EEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCCHHEEHHCCCHHHHHH
VIDTAWVDSLFPKPRSAAQEAKAHHLVHAHTAASDVGAVAEAAHVKTLVLSHLAPADSDP
HHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HRWAAASQGFSGKVIVGRDLLWIPLVPAAPESK
CHHHHHCCCCCCEEEECCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]