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The map label for this gene is nahR [H]

Identifier: 94312645

GI number: 94312645

Start: 255171

End: 256133

Strand: Direct

Name: nahR [H]

Synonym: Rmet_3713

Alternate gene names: 94312645

Gene position: 255171-256133 (Clockwise)

Preceding gene: 94312643

Following gene: 94312648

Centisome position: 9.89

GC content: 60.64

Gene sequence:

>963_bases
ATGGAACTGCAGGACATCGATCTGAACCTGCTTGTCGTATTCAATGAATTATTGCGTCAACGCAAAATGTCCGCCGTGGC
GCGGACGCTTGGGATCTCCCAGCCAGCTGTCAGCAATGCGCTGAATCGCCTGCGCAAATTACTGGACGATGACCTGTTTC
TGCGGACGTCGAAGGGCATGATCCCCACGCAGCTTGCTGGCACGCTAGCCGGGCCTATCACCGAAGCGCTCGATGTCATC
CACCACTCGCTCAACGCACGCGCCACGTTCGACCCCTTGACGAGCACGCGAGCGTTCACCGTGGCGATGACCGATATCGG
CGAGATCTATCTCTTGCCAGGCCTGATGGAGAGGCTTGGCAAACTGGCGCCAGGGGTGAAAATCAGCACGGTGTGCATAC
ACGGCGACTCACTCAAGGGCGCAATGGAAAGTGGTTGTATCGATCTGGCGATCGGATTCCTGCCAGGCCTGACGGCGGGC
TTCTTCCAGCGCCGGCTATTGTCGCAGCAGTACGTGTGCATCTTTCGGAAAGGGCACCCGCTTGGCCGAAGGGATATGAC
GCTGGAAGCGTTCGCCATGGCGGATCGTGTGTCGATCAGCGCGGAAGGCACGGGCCACACCAGGGTGGATGCGGCAATCC
AGCAGGCGGGTGTGACGCGGCGCTCGCGGCTGAGCGTGCCGCATTTCGCGGCGCTGGGTCATATCCTTCAATCGACCGAT
CTGATCGCGGTGGTGCCACAGGCCTATGCGGAGCGCGCGCTGGTGTTGTTCAACCTGGTTTCCGCGCCGTGTCCGGTGAA
GATATCCGAGATCAGTGTCAACGTGTTCTGGCACGCTACCCGTCACCGGGAGGTGGGCAACCAGTGGCTGCGGAACGTGA
TATCCGACAGGTTCGCGGTTTGCCCGATTCCTGAGGCGACGATGTCGCCTCAGGGTTTGGTGGTCAACTGCCGCGGCGAG
TGA

Upstream 100 bases:

>100_bases
TTAACTACGGCGTTGACAATAGGGGCCCGGTTGAATTGCACTATCACCGTTAGTGATAATGCAGCGGTCGTGCCTGATAA
ATCGGGGTGGAGACGTAGTA

Downstream 100 bases:

>100_bases
TGGGGCAGGTGTTGAAGCCGAACACGCGATAGAGCGGGCAGTATCCGAGTAGACCGGTCACGAGCGGCACCGCGCCGATC
CATCCCCAGACGCCGATCTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MELQDIDLNLLVVFNELLRQRKMSAVARTLGISQPAVSNALNRLRKLLDDDLFLRTSKGMIPTQLAGTLAGPITEALDVI
HHSLNARATFDPLTSTRAFTVAMTDIGEIYLLPGLMERLGKLAPGVKISTVCIHGDSLKGAMESGCIDLAIGFLPGLTAG
FFQRRLLSQQYVCIFRKGHPLGRRDMTLEAFAMADRVSISAEGTGHTRVDAAIQQAGVTRRSRLSVPHFAALGHILQSTD
LIAVVPQAYAERALVLFNLVSAPCPVKISEISVNVFWHATRHREVGNQWLRNVISDRFAVCPIPEATMSPQGLVVNCRGE

Sequences:

>Translated_320_residues
MELQDIDLNLLVVFNELLRQRKMSAVARTLGISQPAVSNALNRLRKLLDDDLFLRTSKGMIPTQLAGTLAGPITEALDVI
HHSLNARATFDPLTSTRAFTVAMTDIGEIYLLPGLMERLGKLAPGVKISTVCIHGDSLKGAMESGCIDLAIGFLPGLTAG
FFQRRLLSQQYVCIFRKGHPLGRRDMTLEAFAMADRVSISAEGTGHTRVDAAIQQAGVTRRSRLSVPHFAALGHILQSTD
LIAVVPQAYAERALVLFNLVSAPCPVKISEISVNVFWHATRHREVGNQWLRNVISDRFAVCPIPEATMSPQGLVVNCRGE
>Mature_320_residues
MELQDIDLNLLVVFNELLRQRKMSAVARTLGISQPAVSNALNRLRKLLDDDLFLRTSKGMIPTQLAGTLAGPITEALDVI
HHSLNARATFDPLTSTRAFTVAMTDIGEIYLLPGLMERLGKLAPGVKISTVCIHGDSLKGAMESGCIDLAIGFLPGLTAG
FFQRRLLSQQYVCIFRKGHPLGRRDMTLEAFAMADRVSISAEGTGHTRVDAAIQQAGVTRRSRLSVPHFAALGHILQSTD
LIAVVPQAYAERALVLFNLVSAPCPVKISEISVNVFWHATRHREVGNQWLRNVISDRFAVCPIPEATMSPQGLVVNCRGE

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=26.7558528428094, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081766, Length=265, Percent_Identity=22.2641509433962, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=25.2459016393443, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34943; Mature: 34943

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQDIDLNLLVVFNELLRQRKMSAVARTLGISQPAVSNALNRLRKLLDDDLFLRTSKGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
IPTQLAGTLAGPITEALDVIHHSLNARATFDPLTSTRAFTVAMTDIGEIYLLPGLMERLG
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECCCHHEEHHHHHHHHH
KLAPGVKISTVCIHGDSLKGAMESGCIDLAIGFLPGLTAGFFQRRLLSQQYVCIFRKGHP
HHCCCCEEEEEEEECCCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCC
LGRRDMTLEAFAMADRVSISAEGTGHTRVDAAIQQAGVTRRSRLSVPHFAALGHILQSTD
CCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCC
LIAVVPQAYAERALVLFNLVSAPCPVKISEISVNVFWHATRHREVGNQWLRNVISDRFAV
CEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHCCEEE
CPIPEATMSPQGLVVNCRGE
CCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MELQDIDLNLLVVFNELLRQRKMSAVARTLGISQPAVSNALNRLRKLLDDDLFLRTSKGM
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
IPTQLAGTLAGPITEALDVIHHSLNARATFDPLTSTRAFTVAMTDIGEIYLLPGLMERLG
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECCCHHEEHHHHHHHHH
KLAPGVKISTVCIHGDSLKGAMESGCIDLAIGFLPGLTAGFFQRRLLSQQYVCIFRKGHP
HHCCCCEEEEEEEECCCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCC
LGRRDMTLEAFAMADRVSISAEGTGHTRVDAAIQQAGVTRRSRLSVPHFAALGHILQSTD
CCCCCCHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCC
LIAVVPQAYAERALVLFNLVSAPCPVKISEISVNVFWHATRHREVGNQWLRNVISDRFAV
CEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHCCEEE
CPIPEATMSPQGLVVNCRGE
CCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]