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The map label for this gene is motA [H]

Identifier: 94312619

GI number: 94312619

Start: 226433

End: 227332

Strand: Direct

Name: motA [H]

Synonym: Rmet_3687

Alternate gene names: 94312619

Gene position: 226433-227332 (Clockwise)

Preceding gene: 94312618

Following gene: 94312620

Centisome position: 8.78

GC content: 62.11

Gene sequence:

>900_bases
GTGCCTGACGCGTGTTTTTCAGACGGGGATCCGATCGTGCTTGTAGTTCTTGGCTATGTCGTCGTAGTCGTGGCGGTGCT
GGGCGGTTACGCCCTCACCGGCGGCCACATGGGCGCGCTTTATCAACCGGCGGAGCTCATCATCATCGGCGGTGCCGCGG
TTGGCGCATTCATCAGCTCCAACAGCGGCAAGGCCATCAAGGCCACGATGAAGGCAATGCCCTCGCTGCTGAAGGGCTCC
AAGTACAAGAAGGAACTGTACCTGGACGTGATGGCGCTGCTGTACGTGCTGCTGTCCAAGGCACGTCGCGAGGGCATCCT
GTTCCTCGAAAAGGAAATCGCCGATCCGGCATCGAGCAGTGTCTTCAGTCAGTACCCGCGCATCCTGGCCGACGCCAAGA
TGATGGAATTCCTGACTGACTATCTGCGCATGATGGTCAACGGCAACATGAACGCGTTCGAGATCGAGGCGCTCATGGAC
CACGAAATCGAAACCGTCCGTCATGAAGCCGAGATTCCGGCCCATGCGCTCTCGCGCGTCGGCGACGGCCTGCCCGCCTT
CGGCATCGTGGCCGCGGTGATGGGCGTGGTGCACGCGCTGGCTTCCGCGGACCTGCCTCCGGCCGAACTCGGCGCGCTGA
TCGCCAACGCGATGGTCGGCACGTTCCTGGGCATTCTGCTGGCCTACGGCTTCGTGTCGCCGCTGGCGTCGCGTGTCGAA
CACCAGGTGTCCGAGAGCATCAAGATGTACGAATGCATCAAGGTCACGCTGCTGGCGTCGCTCAATGGTTACGCACCGCT
GGTGGCGGTGGAGTTCGGCCGCAAGGTGCTGTACTCCACGGTACGTCCGTCGTTCCTCGAGCTCGACGACCACGTCCGCG
AAGTCAAGAGCCTGACCTGA

Upstream 100 bases:

>100_bases
AGACCGAAGCCTGATCCATCTGGCCCAACGTCCGCGCAGGAGGTGGGCCCTGGGTTGGTGAGCGGTGACCCCTCTCGCCC
GCGCGGGATGCCCCCGATGC

Downstream 100 bases:

>100_bases
CGGGAGAGCAGTCATGAGCAGCGCCCAGGACCTGCGTCCGATCGTCATCAAGAAGGCGAAATCACATGCCAAGCCGCATG
GCAACCATAGCTGGAAGATC

Product: chemotaxis MotA protein

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPDACFSDGDPIVLVVLGYVVVVVAVLGGYALTGGHMGALYQPAELIIIGGAAVGAFISSNSGKAIKATMKAMPSLLKGS
KYKKELYLDVMALLYVLLSKARREGILFLEKEIADPASSSVFSQYPRILADAKMMEFLTDYLRMMVNGNMNAFEIEALMD
HEIETVRHEAEIPAHALSRVGDGLPAFGIVAAVMGVVHALASADLPPAELGALIANAMVGTFLGILLAYGFVSPLASRVE
HQVSESIKMYECIKVTLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLT

Sequences:

>Translated_299_residues
MPDACFSDGDPIVLVVLGYVVVVVAVLGGYALTGGHMGALYQPAELIIIGGAAVGAFISSNSGKAIKATMKAMPSLLKGS
KYKKELYLDVMALLYVLLSKARREGILFLEKEIADPASSSVFSQYPRILADAKMMEFLTDYLRMMVNGNMNAFEIEALMD
HEIETVRHEAEIPAHALSRVGDGLPAFGIVAAVMGVVHALASADLPPAELGALIANAMVGTFLGILLAYGFVSPLASRVE
HQVSESIKMYECIKVTLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLT
>Mature_298_residues
PDACFSDGDPIVLVVLGYVVVVVAVLGGYALTGGHMGALYQPAELIIIGGAAVGAFISSNSGKAIKATMKAMPSLLKGSK
YKKELYLDVMALLYVLLSKARREGILFLEKEIADPASSSVFSQYPRILADAKMMEFLTDYLRMMVNGNMNAFEIEALMDH
EIETVRHEAEIPAHALSRVGDGLPAFGIVAAVMGVVHALASADLPPAELGALIANAMVGTFLGILLAYGFVSPLASRVEH
QVSESIKMYECIKVTLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLT

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=285, Percent_Identity=63.5087719298246, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32054; Mature: 31923

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDACFSDGDPIVLVVLGYVVVVVAVLGGYALTGGHMGALYQPAELIIIGGAAVGAFISS
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEECCHHHHHHHCC
NSGKAIKATMKAMPSLLKGSKYKKELYLDVMALLYVLLSKARREGILFLEKEIADPASSS
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCHHH
VFSQYPRILADAKMMEFLTDYLRMMVNGNMNAFEIEALMDHEIETVRHEAEIPAHALSRV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GDGLPAFGIVAAVMGVVHALASADLPPAELGALIANAMVGTFLGILLAYGFVSPLASRVE
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQVSESIKMYECIKVTLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLT
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDACFSDGDPIVLVVLGYVVVVVAVLGGYALTGGHMGALYQPAELIIIGGAAVGAFISS
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCEEEEECCHHHHHHHCC
NSGKAIKATMKAMPSLLKGSKYKKELYLDVMALLYVLLSKARREGILFLEKEIADPASSS
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCCHHH
VFSQYPRILADAKMMEFLTDYLRMMVNGNMNAFEIEALMDHEIETVRHEAEIPAHALSRV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GDGLPAFGIVAAVMGVVHALASADLPPAELGALIANAMVGTFLGILLAYGFVSPLASRVE
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HQVSESIKMYECIKVTLLASLNGYAPLVAVEFGRKVLYSTVRPSFLELDDHVREVKSLT
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]