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The map label for this gene is tcp [H]

Identifier: 94312615

GI number: 94312615

Start: 222326

End: 224167

Strand: Direct

Name: tcp [H]

Synonym: Rmet_3683

Alternate gene names: 94312615

Gene position: 222326-224167 (Clockwise)

Preceding gene: 94312614

Following gene: 94312616

Centisome position: 8.62

GC content: 66.29

Gene sequence:

>1842_bases
ATGCAGTGGTTCAATCAACTACGCGTGACAACCAGGCTGATTGCTGGCTTCCTGGTTGTATCCGTCATCGGCGCCATCAT
TGGCTTGCTCGGTGTCGTCAACATGGGGCGCATGACGGAATGGACCGGCAAGATCTACAACAGCGACCTGCAGGCGCTCA
AGGCCGTCCAGGACGGCAACATCAACCTGGTCTATGCCAGCCGCGCGCAGATCGCGCTGCTGTCCGCGTCGACGATGGGC
GAGCGCGCTACCGAGCGGGAGCAGATCGAGAAGTCGCTAAGCACGCTGGAGACCCGCGTCAAGTCGGCTAGGGATTCCTT
CACGACACCGCAAGGCCAGGCGCTGTTCAAACAGTACGAGACGTTGCTGCCGCCGTTCCGGGAACGGATGCAGAAGTACG
TCGAGCTGATCGGCAAGCAGCCGCTGGACACCTCGCAGTTTGAAAGCATCGTGTTCACTGAGAGCGCCGAACTGATCAAG
GACAGCCGCGCACTTGAAGACCTTCTGCTCAAGATAGTGAAGCGCCGCGACGAGCGCGCCAAGGCCAACATGGATGAATC
GACCAGCGTCTACAACCACTCGCGCGTGCTGATGCTGGCGCTGGTGCTGGGCGGCCTGGCGGTGTCGGTGCTGCTGGGTG
GCTTCCTGGCACGCCAGCTTTCGCGCCAGCTCGGTGGCGAGCCGGGCTATGCCGCGGCCATCGCGGCCCGCATCGCGGAG
GGCGACTTTTCGGACGCCGTGAACCTGCGTGCCGGCGACCGGACCAGCCTGCTGCATGCCATGGACCAGATGCAGCAGCA
ACTCTCGCGGATGGTGCGTGACTTCAAGGTGTCCGCCGAATCGATCGGCTCGGCATCGAGCGAGATCGCAGCCGGCAACA
ACGACCTTTCGCAACGCACGGAACAGCAGGCAGCATCGCTCGAGGAAACAGCCTCGAGCATGGCGCAGCTGACCAGCACC
GTGCGCCAGAACGCCGATAACGCGCGTCAGGCCAGCGGGCTGGCCGCCAATGCGTCGGAGACGGCTGTCCGTGGCGGCGA
GGTGGTGGGCCGCGTGGTCCAGACGATGGGCGAGATTAACGACGCGTCGCGCAAGATCGTCGACATCATCGGCGTGATCG
AGGGCATCGCGTTCCAGACCAACATCCTGGCGCTGAATGCCGCCGTGGAAGCCGCGCGGGCGGGCGAGCAGGGCCGTGGC
TTTGCCGTGGTGGCCGGCGAGGTGCGCAGCCTGGCGCAACGCAGCGCCAACGCCGCGAAGGAAATCAAGACGCTGATCGA
CAACTCCGTGGCGCAGGTGGACACCGGCGCCGCACTGGTGTCGCAGGCCGGCACGACGATGGACGAGATCGTGCAGGCCG
TGAAGCGCGTGACCGACATCATGGGCGAGATCAGCGCCGCTTCGGCCGAGCAGAGTTCGGGCATCGAGCAGGTCAACCAG
GCCGTGTCGCAGATGGACGAAGTCACCCAGCAGAACGCGGCGCTGGTCGAGCAGGCCGCCGCTGCCGCAGGTTCGCTCCA
GGATCAGGCCAGCCGCCTGATGGCGTCGGTGTCGGGCTTCCGCCTGTCCCACGGTGATGACGCCGTGCCGGCACTGGCTG
CCCCGGCTCCCGCAGTGCGCCCGGCCGCCCGGCCGTCGGGCGCGAAGCGCCTGCCTGCCCCGGCGCGCCCGGTCAGGAAG
ACGGCTGCCAAGGCCGCGGGCACTGCGCTTGCCGCCACATCGGGTGCCGCCGCCGCTGTTGAGGAATCGGTCGAAGCTGC
CGATAGCCAGTTGAAGCGCCCGGCAATTTCAGCGAGCACGACGATCAGCGCCTCCGACAACGGCGACTGGAGCGCCTTCT
GA

Upstream 100 bases:

>100_bases
GCAAGCGACAGGTGGCGACGATGGGTGAAACGGGGAAAGAAGCCGGGCTGGTCAACGCCTGAGCTTCGGGTCTATTCAAA
TGGAAGGAGGGGGTAGTTCT

Downstream 100 bases:

>100_bases
CCGGACTTCCGGTAGCCGCTTGGCGGCACCGCAAGGAAGGGTGACGCACGTCCCGGCGCCAGGCATCGAGCCAGCCAGCG
CCGGGGCGCTTTTTCGTCCA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MQWFNQLRVTTRLIAGFLVVSVIGAIIGLLGVVNMGRMTEWTGKIYNSDLQALKAVQDGNINLVYASRAQIALLSASTMG
ERATEREQIEKSLSTLETRVKSARDSFTTPQGQALFKQYETLLPPFRERMQKYVELIGKQPLDTSQFESIVFTESAELIK
DSRALEDLLLKIVKRRDERAKANMDESTSVYNHSRVLMLALVLGGLAVSVLLGGFLARQLSRQLGGEPGYAAAIAARIAE
GDFSDAVNLRAGDRTSLLHAMDQMQQQLSRMVRDFKVSAESIGSASSEIAAGNNDLSQRTEQQAASLEETASSMAQLTST
VRQNADNARQASGLAANASETAVRGGEVVGRVVQTMGEINDASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRG
FAVVAGEVRSLAQRSANAAKEIKTLIDNSVAQVDTGAALVSQAGTTMDEIVQAVKRVTDIMGEISAASAEQSSGIEQVNQ
AVSQMDEVTQQNAALVEQAAAAAGSLQDQASRLMASVSGFRLSHGDDAVPALAAPAPAVRPAARPSGAKRLPAPARPVRK
TAAKAAGTALAATSGAAAAVEESVEAADSQLKRPAISASTTISASDNGDWSAF

Sequences:

>Translated_613_residues
MQWFNQLRVTTRLIAGFLVVSVIGAIIGLLGVVNMGRMTEWTGKIYNSDLQALKAVQDGNINLVYASRAQIALLSASTMG
ERATEREQIEKSLSTLETRVKSARDSFTTPQGQALFKQYETLLPPFRERMQKYVELIGKQPLDTSQFESIVFTESAELIK
DSRALEDLLLKIVKRRDERAKANMDESTSVYNHSRVLMLALVLGGLAVSVLLGGFLARQLSRQLGGEPGYAAAIAARIAE
GDFSDAVNLRAGDRTSLLHAMDQMQQQLSRMVRDFKVSAESIGSASSEIAAGNNDLSQRTEQQAASLEETASSMAQLTST
VRQNADNARQASGLAANASETAVRGGEVVGRVVQTMGEINDASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRG
FAVVAGEVRSLAQRSANAAKEIKTLIDNSVAQVDTGAALVSQAGTTMDEIVQAVKRVTDIMGEISAASAEQSSGIEQVNQ
AVSQMDEVTQQNAALVEQAAAAAGSLQDQASRLMASVSGFRLSHGDDAVPALAAPAPAVRPAARPSGAKRLPAPARPVRK
TAAKAAGTALAATSGAAAAVEESVEAADSQLKRPAISASTTISASDNGDWSAF
>Mature_613_residues
MQWFNQLRVTTRLIAGFLVVSVIGAIIGLLGVVNMGRMTEWTGKIYNSDLQALKAVQDGNINLVYASRAQIALLSASTMG
ERATEREQIEKSLSTLETRVKSARDSFTTPQGQALFKQYETLLPPFRERMQKYVELIGKQPLDTSQFESIVFTESAELIK
DSRALEDLLLKIVKRRDERAKANMDESTSVYNHSRVLMLALVLGGLAVSVLLGGFLARQLSRQLGGEPGYAAAIAARIAE
GDFSDAVNLRAGDRTSLLHAMDQMQQQLSRMVRDFKVSAESIGSASSEIAAGNNDLSQRTEQQAASLEETASSMAQLTST
VRQNADNARQASGLAANASETAVRGGEVVGRVVQTMGEINDASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRG
FAVVAGEVRSLAQRSANAAKEIKTLIDNSVAQVDTGAALVSQAGTTMDEIVQAVKRVTDIMGEISAASAEQSSGIEQVNQ
AVSQMDEVTQQNAALVEQAAAAAGSLQDQASRLMASVSGFRLSHGDDAVPALAAPAPAVRPAARPSGAKRLPAPARPVRK
TAAKAAGTALAATSGAAAAVEESVEAADSQLKRPAISASTTISASDNGDWSAF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=319, Percent_Identity=60.1880877742947, Blast_Score=318, Evalue=8e-88,
Organism=Escherichia coli, GI1787690, Length=459, Percent_Identity=45.7516339869281, Blast_Score=312, Evalue=5e-86,
Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=62.6623376623377, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1788194, Length=536, Percent_Identity=41.6044776119403, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1789453, Length=285, Percent_Identity=42.1052631578947, Blast_Score=213, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 64629; Mature: 64629

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWFNQLRVTTRLIAGFLVVSVIGAIIGLLGVVNMGRMTEWTGKIYNSDLQALKAVQDGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
INLVYASRAQIALLSASTMGERATEREQIEKSLSTLETRVKSARDSFTTPQGQALFKQYE
EEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
TLLPPFRERMQKYVELIGKQPLDTSQFESIVFTESAELIKDSRALEDLLLKIVKRRDERA
HHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
KANMDESTSVYNHSRVLMLALVLGGLAVSVLLGGFLARQLSRQLGGEPGYAAAIAARIAE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GDFSDAVNLRAGDRTSLLHAMDQMQQQLSRMVRDFKVSAESIGSASSEIAAGNNDLSQRT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHH
EQQAASLEETASSMAQLTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVQTMGEIN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIKTLIDNSVAQVDTGAALVSQAGTTMDEIVQAVKRVTDIMGEISAASAEQSSGIEQVNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
AVSQMDEVTQQNAALVEQAAAAAGSLQDQASRLMASVSGFRLSHGDDAVPALAAPAPAVR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEECCCCCCCCHHCCCCCCCC
PAARPSGAKRLPAPARPVRKTAAKAAGTALAATSGAAAAVEESVEAADSQLKRPAISAST
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
TISASDNGDWSAF
EEECCCCCCCCCC
>Mature Secondary Structure
MQWFNQLRVTTRLIAGFLVVSVIGAIIGLLGVVNMGRMTEWTGKIYNSDLQALKAVQDGN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
INLVYASRAQIALLSASTMGERATEREQIEKSLSTLETRVKSARDSFTTPQGQALFKQYE
EEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
TLLPPFRERMQKYVELIGKQPLDTSQFESIVFTESAELIKDSRALEDLLLKIVKRRDERA
HHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
KANMDESTSVYNHSRVLMLALVLGGLAVSVLLGGFLARQLSRQLGGEPGYAAAIAARIAE
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GDFSDAVNLRAGDRTSLLHAMDQMQQQLSRMVRDFKVSAESIGSASSEIAAGNNDLSQRT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHH
EQQAASLEETASSMAQLTSTVRQNADNARQASGLAANASETAVRGGEVVGRVVQTMGEIN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DASRKIVDIIGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSANAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIKTLIDNSVAQVDTGAALVSQAGTTMDEIVQAVKRVTDIMGEISAASAEQSSGIEQVNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHH
AVSQMDEVTQQNAALVEQAAAAAGSLQDQASRLMASVSGFRLSHGDDAVPALAAPAPAVR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEECCCCCCCCHHCCCCCCCC
PAARPSGAKRLPAPARPVRKTAAKAAGTALAATSGAAAAVEESVEAADSQLKRPAISAST
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCC
TISASDNGDWSAF
EEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]