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The map label for this gene is yycF [H]

Identifier: 93006927

GI number: 93006927

Start: 2576638

End: 2577360

Strand: Direct

Name: yycF [H]

Synonym: Pcryo_2103

Alternate gene names: 93006927

Gene position: 2576638-2577360 (Clockwise)

Preceding gene: 93006926

Following gene: 93006928

Centisome position: 84.21

GC content: 43.85

Gene sequence:

>723_bases
ATGAGTAAGCAGATTTTGTTAATTGAAGATGATCCAGATTTAGCAGAATTAATCAGTGATTATCTGACCATGAATTATTA
TGATGTGCATCATGCAGGTCTTGGTCAAGAAGGTCTGGATTTATTAGACACCAAAGAGCGTGATATTGACTTGGTAGTAC
TTGACCTCATGCTACCCGACATGGATGGTATGCAAGTTTGCCAAAAAATCCGTGGCAATAAAAACAATATGACCAATAAA
GTGCCGATCATTATGTTGACAGCAAAAGGTGATACCACAGACCGCGTATTGGGTCTTGAGATGGGCGCTGATGACTATAT
TGCCAAACCGTTTGAGCCGCGTGAACTGTTAGCTCGTATTCGTGCGGTTATTCGCCGCCATGAGCAGCCAAACCAAGCGG
ACAGTCAGTCAGATAGCTTAACTTTTGGTCGTTTGAGCGTGTTCCCTGACAGTCATGAAGTGACTATCGATGATTTACCT
GTACGCTTGACAACGCATCAGTTTCAATTGCTGCATTATTTTGCCACTCATTCAGGCAAAGTACTAAACCGCGAGCAATT
ATGGCAAGCTATGCCAAATGATGACAGCTCAGACAATATTGATCGCGCCATTGACGTACATATCTCGCGTCTTCGTGCGT
TGATTGAAGACAATCCCCGTCAACCAAAGCGTATTATTACAGTGCGCGGCGTCGGTTATCAGTTTGCCACTGACCAAGTG
TAG

Upstream 100 bases:

>100_bases
TATGAGCATTTGGGATAATTGAAAACTAAGGGCAGACGCCACTTTTATAAATTGTAAAAGTGCATTAAGACAAATTATAA
CAACAACTAGAGGAAACATT

Downstream 100 bases:

>100_bases
TCAGTAGTAAACTGTTGGTAAATAAACAGTCAAACAGCTTTAAAATAGTTCATTAAAAGGGGTATCATATGTATGATAAC
CCCTTTTATGTTTGATCATA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSKQILLIEDDPDLAELISDYLTMNYYDVHHAGLGQEGLDLLDTKERDIDLVVLDLMLPDMDGMQVCQKIRGNKNNMTNK
VPIIMLTAKGDTTDRVLGLEMGADDYIAKPFEPRELLARIRAVIRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDLP
VRLTTHQFQLLHYFATHSGKVLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV

Sequences:

>Translated_240_residues
MSKQILLIEDDPDLAELISDYLTMNYYDVHHAGLGQEGLDLLDTKERDIDLVVLDLMLPDMDGMQVCQKIRGNKNNMTNK
VPIIMLTAKGDTTDRVLGLEMGADDYIAKPFEPRELLARIRAVIRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDLP
VRLTTHQFQLLHYFATHSGKVLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV
>Mature_239_residues
SKQILLIEDDPDLAELISDYLTMNYYDVHHAGLGQEGLDLLDTKERDIDLVVLDLMLPDMDGMQVCQKIRGNKNNMTNKV
PIIMLTAKGDTTDRVLGLEMGADDYIAKPFEPRELLARIRAVIRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDLPV
RLTTHQFQLLHYFATHSGKVLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=42.1940928270042, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786599, Length=241, Percent_Identity=39.0041493775934, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI87082012, Length=236, Percent_Identity=38.5593220338983, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=37.603305785124, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=40.343347639485, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786784, Length=242, Percent_Identity=39.2561983471074, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=32.3275862068966, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=37.6569037656904, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787229, Length=240, Percent_Identity=30.4166666666667, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790863, Length=241, Percent_Identity=31.1203319502075, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=31.4655172413793, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=34.7280334728033, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=31.7596566523605, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=241, Percent_Identity=30.2904564315353, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=29.5652173913043, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=106, Percent_Identity=37.7358490566038, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27362; Mature: 27231

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQILLIEDDPDLAELISDYLTMNYYDVHHAGLGQEGLDLLDTKERDIDLVVLDLMLPD
CCCCEEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCCHHHCCCCCCCCEEEEEECCCC
MDGMQVCQKIRGNKNNMTNKVPIIMLTAKGDTTDRVLGLEMGADDYIAKPFEPRELLARI
CCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
RAVIRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDLPVRLTTHQFQLLHYFATHSGK
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCEEEEHHHHHHHHHHHHCCCC
VLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV
EECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCC
>Mature Secondary Structure 
SKQILLIEDDPDLAELISDYLTMNYYDVHHAGLGQEGLDLLDTKERDIDLVVLDLMLPD
CCCEEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCCHHHCCCCCCCCEEEEEECCCC
MDGMQVCQKIRGNKNNMTNKVPIIMLTAKGDTTDRVLGLEMGADDYIAKPFEPRELLARI
CCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
RAVIRRHEQPNQADSQSDSLTFGRLSVFPDSHEVTIDDLPVRLTTHQFQLLHYFATHSGK
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCEEEEHHHHHHHHHHHHCCCC
VLNREQLWQAMPNDDSSDNIDRAIDVHISRLRALIEDNPRQPKRIITVRGVGYQFATDQV
EECHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]