Click here to switch to the map view.

The map label for this gene is insK [H]

Identifier: 93006901

GI number: 93006901

Start: 2543859

End: 2544644

Strand: Direct

Name: insK [H]

Synonym: Pcryo_2077

Alternate gene names: 93006901

Gene position: 2543859-2544644 (Clockwise)

Preceding gene: 93006900

Following gene: 93006903

Centisome position: 83.14

GC content: 39.06

Gene sequence:

>786_bases
ATGGCTAAAAGTGTCTTTTACTACCATAGGTGTCAGTTTGACGTTAAAGACAAATATGGAGACTTAAAACAGCGTATTAC
TGAGCTTTACCATCAGCATAAAGGCAGGTATGGTTATCGTAGAGTCACGGCTGCATTAAAGCAGCTAGATTGTCATCATA
ACCATAAGCTCATCGCTAAGCTTATGCATGACATGAAGCTTAGCGCAAAGATAAGACGTCAGAAGTATCGCTCCTATAAA
GGACAACAAGGTAAGATTGCGAAGAACTATTTAAAACGCCAGTTTCATGCAGATAAACCAAATAAGCGCTGGCTGACCGA
TATTACTGAGTTTAAGGTGGGTGATGATAAGCTGTATTTGTCACCCATACTTGATTGTTATAACAATGAGATTGTCAGTT
ATACACTCTCAAAGAGACCCACTTATGACTTAGTTGGCAAGATGCTAGAGGATGCTTTGGCAAAGACGAAAGCGTGCCGT
GATAACAAGTTAATGCTGCACTCTGATCAAGGATGGCATTATCAAATGAGACTGTTTGGACAGGTGCTGAAACAGCATGG
TATTAAGCAAAGTATGAGCAGAAAAGGCAACTGTTTGGATAATGCGCTCATGGAGGGGTTCTTTGGTACCCTAAAGTGTG
AGACGATTTATATTGAAAAGCCTAATTCGATTGAAGGTTTAGAGAAACAGATTCATGAGTATATTCACTACTATAATCAT
GAAAGAATTCAACTCAAACTAAAAGGACTGAGTCCTGTTAAGTACAGAACTCAGTCCTTGATATAA

Upstream 100 bases:

>100_bases
ATGCCTTGCTCAAAGCGGAGGAACAAGCAGGCAAAAAGCAAGGCTCATCGAAGCACTAAGACAAGAGCACCCTTTATCTG
CTTTGCTAAACATCGCTAAG

Downstream 100 bases:

>100_bases
ACTAAACCGTCCAACATTTGGGGGTCAGTTCATTAATGGGGTTTTTTATACTTTATTTAGTATGATGAATAAGCAGATAC
TGCCTTCTGTCACACTATCC

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAKSVFYYHRCQFDVKDKYGDLKQRITELYHQHKGRYGYRRVTAALKQLDCHHNHKLIAKLMHDMKLSAKIRRQKYRSYK
GQQGKIAKNYLKRQFHADKPNKRWLTDITEFKVGDDKLYLSPILDCYNNEIVSYTLSKRPTYDLVGKMLEDALAKTKACR
DNKLMLHSDQGWHYQMRLFGQVLKQHGIKQSMSRKGNCLDNALMEGFFGTLKCETIYIEKPNSIEGLEKQIHEYIHYYNH
ERIQLKLKGLSPVKYRTQSLI

Sequences:

>Translated_261_residues
MAKSVFYYHRCQFDVKDKYGDLKQRITELYHQHKGRYGYRRVTAALKQLDCHHNHKLIAKLMHDMKLSAKIRRQKYRSYK
GQQGKIAKNYLKRQFHADKPNKRWLTDITEFKVGDDKLYLSPILDCYNNEIVSYTLSKRPTYDLVGKMLEDALAKTKACR
DNKLMLHSDQGWHYQMRLFGQVLKQHGIKQSMSRKGNCLDNALMEGFFGTLKCETIYIEKPNSIEGLEKQIHEYIHYYNH
ERIQLKLKGLSPVKYRTQSLI
>Mature_260_residues
AKSVFYYHRCQFDVKDKYGDLKQRITELYHQHKGRYGYRRVTAALKQLDCHHNHKLIAKLMHDMKLSAKIRRQKYRSYKG
QQGKIAKNYLKRQFHADKPNKRWLTDITEFKVGDDKLYLSPILDCYNNEIVSYTLSKRPTYDLVGKMLEDALAKTKACRD
NKLMLHSDQGWHYQMRLFGQVLKQHGIKQSMSRKGNCLDNALMEGFFGTLKCETIYIEKPNSIEGLEKQIHEYIHYYNHE
RIQLKLKGLSPVKYRTQSLI

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=209, Percent_Identity=28.2296650717703, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1789981, Length=259, Percent_Identity=51.3513513513513, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1788405, Length=237, Percent_Identity=31.6455696202532, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787263, Length=237, Percent_Identity=31.6455696202532, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786753, Length=237, Percent_Identity=31.6455696202532, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786570, Length=237, Percent_Identity=31.6455696202532, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1786490, Length=237, Percent_Identity=31.6455696202532, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31014; Mature: 30883

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSVFYYHRCQFDVKDKYGDLKQRITELYHQHKGRYGYRRVTAALKQLDCHHNHKLIAK
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
LMHDMKLSAKIRRQKYRSYKGQQGKIAKNYLKRQFHADKPNKRWLTDITEFKVGDDKLYL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHH
SPILDCYNNEIVSYTLSKRPTYDLVGKMLEDALAKTKACRDNKLMLHSDQGWHYQMRLFG
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
QVLKQHGIKQSMSRKGNCLDNALMEGFFGTLKCETIYIEKPNSIEGLEKQIHEYIHYYNH
HHHHHHCHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
ERIQLKLKGLSPVKYRTQSLI
CEEEEEECCCCCHHHHHHHCC
>Mature Secondary Structure 
AKSVFYYHRCQFDVKDKYGDLKQRITELYHQHKGRYGYRRVTAALKQLDCHHNHKLIAK
CCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHH
LMHDMKLSAKIRRQKYRSYKGQQGKIAKNYLKRQFHADKPNKRWLTDITEFKVGDDKLYL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHH
SPILDCYNNEIVSYTLSKRPTYDLVGKMLEDALAKTKACRDNKLMLHSDQGWHYQMRLFG
HHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
QVLKQHGIKQSMSRKGNCLDNALMEGFFGTLKCETIYIEKPNSIEGLEKQIHEYIHYYNH
HHHHHHCHHHHHHHCCCHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCC
ERIQLKLKGLSPVKYRTQSLI
CEEEEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]