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The map label for this gene is luxQ [H]

Identifier: 93005487

GI number: 93005487

Start: 778073

End: 779929

Strand: Direct

Name: luxQ [H]

Synonym: Pcryo_0657

Alternate gene names: 93005487

Gene position: 778073-779929 (Clockwise)

Preceding gene: 93005486

Following gene: 93005490

Centisome position: 25.43

GC content: 40.71

Gene sequence:

>1857_bases
ATGAACAACCGCCCGCATCAAACACTTCCTACGCTTATCTGGCACTCTATCATGCAGACCATGGTCTTGGCTGTTTTGGC
AGGTTTATTAGTGTCTTTTATTTATGGCTTTGTTCACTATTACAAAGACACACGCCAGCATATTCAGGATTTAGCGACAT
TACTGACTATCAGCGCATCGATAGCAGATTCCACCGATATCGTCGATGAACAAATACGTTTTTTATTAGAAAAAGAGCAA
GGCATTGAGAGTATTTTATTTTATACCACCTCTCAGCCTGTCGTTGATGCCAATCAATTAAGAGACGACTGGAAGAATGC
TTTGTTTGCCAATAGGATTAGCTTTAATTATCCTGTCGTTGGCGATCCTACCAATAAGATTCTCTCATCGAAAGAAGATG
CTTTGGTTGGTTATTTGAATATCACTTTAGATGTGGCGACGCTGCGTGAGAATTGGATTAAAAAGAACCTACTGCTATGG
CTTATGACAACGCTATTGGCGATTATTTGGGCGTTGTTTATCCTGCGTAAGCTGAATTGGCCGTCAAAAGATATCGCCAA
TCTGACGGCAGCTTGCGATATAGTTATAAAAAATCCAGATATTGAGCAGTTACCTCTGATTCAACAGCGTTTTGAGTTTC
AGGAGTTGGTACAGATTAAACAGGCTTTTATTACCCTATTTGATCGCCTGCAAATCGCAAAGCAAGATTATCAGGCACTT
GCGGCTTTCGAGCAACAACTGCATCATAAAGATGTGTCGCTTGATGTGCAGCTACATAATTTTCAAAGTATGATTACTCA
TGAGCTAAAAACTTCGCTAAATGCGATCGTTGGCGGCTTACAGCTACTAGATGATGAAAAGTTAAATCACGAGCAAAGAG
ACGCGGTTGATATTATTCGAGAGGGTAGTGACAAACTGGTCTTAACCTTAGATCAAATTATTCAGTTAAATCAAATCCAG
AAAGGTCAAATCAGCCTACATGTGCACGAATTTAATCCATTGCAACTAATCGCTGACTTATTGGCAGAGTTTGAGCCAGC
TATTAAGAAAAAGGGCTTAACGTTAATCAGTCATATCCATCATATCGATTATATCCTCGAAGGCGATGCTGAAAGAATAC
AGCAAATTTTAGCGATACTGGTCAGTAACGCCATGAAGTTCACACCAGCAGGTCAAATCACCATTACGTCACAACTGACC
CATTTTGATAACAGCAATCGCTGGCAGATTAGCGTAAAGGACACTGGTATCGGGATTGATAGCAGTTTTATTGAAGATAT
TTTTAATCCATTTTTTCAGGTAGATTCATCGCAAACCCGTCAATACGAAGGGTCGGGAATTGGTCTGCCAGTGGTTAAGC
AAATGGCTCAGCTGATGGGGGCTAGCATTGAAGTAGATAGCACTTTAGGTATTGGTACGAATTTTACAGTTACTATTCCT
ATGTCTAATCAACACCATTCTCAACAACAGCAACATCTGCGCGGCTTAAGAATTATTTATTACTACTATCATGAAAAAGG
GTTGTTGGTAGATCAATTACAGCATTTGGGTGCTGATGTGGCCTGCTATCAACATGAACAGCTGGTTATCGATGAGGTAC
ATGCGAAGCAATTTGACATGCTGATGTTTGCAGAAGATGTGTTCCCCAGAAAAGCAGCCTCATTAGCGAGTCATATTCGT
GCGGCTGAGACAGAGTATCGAACGTTACTGGTGTTTTGGTATCCACAGCAGCAAGCAAAACATTTAGCCGATTTTGAGTT
TGGTCTAAAGGCTGCAGGTATAGACTACTGCGAAGTTGCCAAATACGAAGACAAAGCGTTAAGTGATTTACTAAAAAGCT
GGCTGACATGGTCATAA

Upstream 100 bases:

>100_bases
GGGCACTATTCATTAGTTGCCTTAAAATATCAATTTTCACTTATAACCGCTATAAAATACCTGTACTATAATCAAAAGTT
GTCTAACTCAGTTGAGTGAT

Downstream 100 bases:

>100_bases
AAATAGCGAGAAATATAAAATTTTAAACATAAAAAAGACGCCTTGATATGAGACGTCTTTTTTATGTTGAACTTCATGAT
AAAAGCATTATTTCAAAATG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MNNRPHQTLPTLIWHSIMQTMVLAVLAGLLVSFIYGFVHYYKDTRQHIQDLATLLTISASIADSTDIVDEQIRFLLEKEQ
GIESILFYTTSQPVVDANQLRDDWKNALFANRISFNYPVVGDPTNKILSSKEDALVGYLNITLDVATLRENWIKKNLLLW
LMTTLLAIIWALFILRKLNWPSKDIANLTAACDIVIKNPDIEQLPLIQQRFEFQELVQIKQAFITLFDRLQIAKQDYQAL
AAFEQQLHHKDVSLDVQLHNFQSMITHELKTSLNAIVGGLQLLDDEKLNHEQRDAVDIIREGSDKLVLTLDQIIQLNQIQ
KGQISLHVHEFNPLQLIADLLAEFEPAIKKKGLTLISHIHHIDYILEGDAERIQQILAILVSNAMKFTPAGQITITSQLT
HFDNSNRWQISVKDTGIGIDSSFIEDIFNPFFQVDSSQTRQYEGSGIGLPVVKQMAQLMGASIEVDSTLGIGTNFTVTIP
MSNQHHSQQQQHLRGLRIIYYYYHEKGLLVDQLQHLGADVACYQHEQLVIDEVHAKQFDMLMFAEDVFPRKAASLASHIR
AAETEYRTLLVFWYPQQQAKHLADFEFGLKAAGIDYCEVAKYEDKALSDLLKSWLTWS

Sequences:

>Translated_618_residues
MNNRPHQTLPTLIWHSIMQTMVLAVLAGLLVSFIYGFVHYYKDTRQHIQDLATLLTISASIADSTDIVDEQIRFLLEKEQ
GIESILFYTTSQPVVDANQLRDDWKNALFANRISFNYPVVGDPTNKILSSKEDALVGYLNITLDVATLRENWIKKNLLLW
LMTTLLAIIWALFILRKLNWPSKDIANLTAACDIVIKNPDIEQLPLIQQRFEFQELVQIKQAFITLFDRLQIAKQDYQAL
AAFEQQLHHKDVSLDVQLHNFQSMITHELKTSLNAIVGGLQLLDDEKLNHEQRDAVDIIREGSDKLVLTLDQIIQLNQIQ
KGQISLHVHEFNPLQLIADLLAEFEPAIKKKGLTLISHIHHIDYILEGDAERIQQILAILVSNAMKFTPAGQITITSQLT
HFDNSNRWQISVKDTGIGIDSSFIEDIFNPFFQVDSSQTRQYEGSGIGLPVVKQMAQLMGASIEVDSTLGIGTNFTVTIP
MSNQHHSQQQQHLRGLRIIYYYYHEKGLLVDQLQHLGADVACYQHEQLVIDEVHAKQFDMLMFAEDVFPRKAASLASHIR
AAETEYRTLLVFWYPQQQAKHLADFEFGLKAAGIDYCEVAKYEDKALSDLLKSWLTWS
>Mature_618_residues
MNNRPHQTLPTLIWHSIMQTMVLAVLAGLLVSFIYGFVHYYKDTRQHIQDLATLLTISASIADSTDIVDEQIRFLLEKEQ
GIESILFYTTSQPVVDANQLRDDWKNALFANRISFNYPVVGDPTNKILSSKEDALVGYLNITLDVATLRENWIKKNLLLW
LMTTLLAIIWALFILRKLNWPSKDIANLTAACDIVIKNPDIEQLPLIQQRFEFQELVQIKQAFITLFDRLQIAKQDYQAL
AAFEQQLHHKDVSLDVQLHNFQSMITHELKTSLNAIVGGLQLLDDEKLNHEQRDAVDIIREGSDKLVLTLDQIIQLNQIQ
KGQISLHVHEFNPLQLIADLLAEFEPAIKKKGLTLISHIHHIDYILEGDAERIQQILAILVSNAMKFTPAGQITITSQLT
HFDNSNRWQISVKDTGIGIDSSFIEDIFNPFFQVDSSQTRQYEGSGIGLPVVKQMAQLMGASIEVDSTLGIGTNFTVTIP
MSNQHHSQQQQHLRGLRIIYYYYHEKGLLVDQLQHLGADVACYQHEQLVIDEVHAKQFDMLMFAEDVFPRKAASLASHIR
AAETEYRTLLVFWYPQQQAKHLADFEFGLKAAGIDYCEVAKYEDKALSDLLKSWLTWS

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=357, Percent_Identity=26.890756302521, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI87081816, Length=224, Percent_Identity=30.8035714285714, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789149, Length=517, Percent_Identity=23.7911025145068, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI48994928, Length=222, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=28.8135593220339, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=26.8085106382979, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=239, Percent_Identity=27.1966527196653, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=25.6756756756757, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=23.963133640553, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=24.8927038626609, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=24.4635193133047, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=82, Percent_Identity=42.6829268292683, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70570; Mature: 70570

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRPHQTLPTLIWHSIMQTMVLAVLAGLLVSFIYGFVHYYKDTRQHIQDLATLLTISAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IADSTDIVDEQIRFLLEKEQGIESILFYTTSQPVVDANQLRDDWKNALFANRISFNYPVV
HCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
GDPTNKILSSKEDALVGYLNITLDVATLRENWIKKNLLLWLMTTLLAIIWALFILRKLNW
CCCHHHHHCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSKDIANLTAACDIVIKNPDIEQLPLIQQRFEFQELVQIKQAFITLFDRLQIAKQDYQAL
CCHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFEQQLHHKDVSLDVQLHNFQSMITHELKTSLNAIVGGLQLLDDEKLNHEQRDAVDIIR
HHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHH
EGSDKLVLTLDQIIQLNQIQKGQISLHVHEFNPLQLIADLLAEFEPAIKKKGLTLISHIH
CCCCCEEEEHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HIDYILEGDAERIQQILAILVSNAMKFTPAGQITITSQLTHFDNSNRWQISVKDTGIGID
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCEEEEEEECCCCCCC
SSFIEDIFNPFFQVDSSQTRQYEGSGIGLPVVKQMAQLMGASIEVDSTLGIGTNFTVTIP
HHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEE
MSNQHHSQQQQHLRGLRIIYYYYHEKGLLVDQLQHLGADVACYQHEQLVIDEVHAKQFDM
CCCCHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHH
LMFAEDVFPRKAASLASHIRAAETEYRTLLVFWYPQQQAKHLADFEFGLKAAGIDYCEVA
HHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCHHCCCCHHHHH
KYEDKALSDLLKSWLTWS
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNRPHQTLPTLIWHSIMQTMVLAVLAGLLVSFIYGFVHYYKDTRQHIQDLATLLTISAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IADSTDIVDEQIRFLLEKEQGIESILFYTTSQPVVDANQLRDDWKNALFANRISFNYPVV
HCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
GDPTNKILSSKEDALVGYLNITLDVATLRENWIKKNLLLWLMTTLLAIIWALFILRKLNW
CCCHHHHHCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PSKDIANLTAACDIVIKNPDIEQLPLIQQRFEFQELVQIKQAFITLFDRLQIAKQDYQAL
CCHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFEQQLHHKDVSLDVQLHNFQSMITHELKTSLNAIVGGLQLLDDEKLNHEQRDAVDIIR
HHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHH
EGSDKLVLTLDQIIQLNQIQKGQISLHVHEFNPLQLIADLLAEFEPAIKKKGLTLISHIH
CCCCCEEEEHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HIDYILEGDAERIQQILAILVSNAMKFTPAGQITITSQLTHFDNSNRWQISVKDTGIGID
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCCCCCCEEEEEEECCCCCCC
SSFIEDIFNPFFQVDSSQTRQYEGSGIGLPVVKQMAQLMGASIEVDSTLGIGTNFTVTIP
HHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEEE
MSNQHHSQQQQHLRGLRIIYYYYHEKGLLVDQLQHLGADVACYQHEQLVIDEVHAKQFDM
CCCCHHHHHHHHHCCEEEEEEEEECCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHH
LMFAEDVFPRKAASLASHIRAAETEYRTLLVFWYPQQQAKHLADFEFGLKAAGIDYCEVA
HHHHHHHCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHCCCHHCCCCHHHHH
KYEDKALSDLLKSWLTWS
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]