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The map label for this gene is engA

Identifier: 93005486

GI number: 93005486

Start: 776402

End: 777844

Strand: Direct

Name: engA

Synonym: Pcryo_0656

Alternate gene names: 93005486

Gene position: 776402-777844 (Clockwise)

Preceding gene: 93005485

Following gene: 93005487

Centisome position: 25.37

GC content: 44.01

Gene sequence:

>1443_bases
ATGAGTATCAAGCCTGTGGTCGCCTTAATTGGTCGTCCAAACGTCGGTAAATCCACCTTATTTAATCAGTTCACTAAAAG
TCGGCAGGCATTGGTTGCTGATTTGTCAGGATTGACTCGTGACCGTCAATACGGTGATGCGACCTACGAAGACAAAGCTT
TTATTGTCGTTGATACCGGTGGTATTGGTGAAGCGGACGATGGCAGAGGCGATATTGATGATTATATGTCTGAACAGTCG
TATACTGCTATTCATGAAGCCGATATCATTGTATTTGTGGTTGATGCACGCGCAGGGATGATTGGTGCTGATGCTGAGAT
TGGTAAGTTTTTACACACCCTTGGCAAGCCTGTATATGTTGTTGCCAACAAAGTCGATGGTGTGCATGATTCGGCGCCTG
CTGAATTTTATGCATTAGGTCTAGGCGAACCATATCCAATGGCGGCAAGTCACGGTCGCGGGGTCGGCAATCTGCTCGAA
GTATTAACCGCTGATATGCCTAGTCAGGAAAATGTGGTTGAGCCCAGAGGGTTGAAACTTGCTATTATCGGTCGTCCAAA
CGTTGGTAAATCGACGCTAGTCAACCGTTTGCTTGGTGAAGACCGCGTTGTCGTCTTTGATATGCCTGGTACCACTCGTG
ATAGTATCTATATCCCATATACGCGTGAAGGTAAAGATTACGTATTGATTGATACGGCTGGTGTTCGTCGCCGTGGTAAA
ATCGATGAAAAAGTTGAGAAATTCTCAGTTATCAAAACCTTACAAGCGATTGAAGACTCTAATGTAACCGTTATTGTTAT
TGATGCTCATGAAGGTATTGTTGATCAAGATTTGCATATGATTGGCTATGCGCTGGACGCAGGTCGTGCGCTAGTGGTTG
CGATTAATAAGTGGGACGGTTTGACTGCCGATCAAAAGAACTATATCAAAATTGAGATGGATCGCCGTTTTAATTTTATC
CCTTATGTAAAAGTCCATCAAATCTCAGCATTACATGGTACGGGCGTGGGTAATTTATATCCGTCTATTTTGCGTGCTTA
TCAATCGTCAATGTTTGAGGTATCAACCAACCGTTTGACGCAGATTTTGCAAGATGCTGTTACTGCCAATCCACCGCCAA
CGGTCGCTGGTCGCCGTATTAAGTTGCGTTATGCGCATATCGGTGGACACAATCCGCCCGTTATCGTCATTCATGGTAAT
CAAACTGGTTCGTTACCTAAGAGCTATCAGCGCTATCTTGAAAATCAATTCCGTCAGGTATTCAAGTTAGAAGGCACGCC
ACTAAACGTGGTCTTTAAACTGAATGAAAACCCGTATGCTAATAAAAGCGATACGCCGACCAAAGCCAAAACCCAACAGT
TACGTCAACGTGAACGTAATCGTGCGCAGAAATTTACCACCAAAGATAAGCCGAGATTTACCAACAAAGATAAAAAGCGT
TAA

Upstream 100 bases:

>100_bases
CTACTTTTTGCTTTTTTATAACGGTAAATTTACGTTGTAAAAGAGATTGTATCTAAGTAGTTGCACTGTCCGTCATTGTG
CCTTTCACTGAGAGTAACCC

Downstream 100 bases:

>100_bases
TGCAATCATATTTGCGCTTTTGGGTGGTAGTAGCTAGCCGATAAAAGCCCTTTGATACTATTTATCAGGCTTTTTAAATG
TGCTTCGTCATGACGGCTGT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MSIKPVVALIGRPNVGKSTLFNQFTKSRQALVADLSGLTRDRQYGDATYEDKAFIVVDTGGIGEADDGRGDIDDYMSEQS
YTAIHEADIIVFVVDARAGMIGADAEIGKFLHTLGKPVYVVANKVDGVHDSAPAEFYALGLGEPYPMAASHGRGVGNLLE
VLTADMPSQENVVEPRGLKLAIIGRPNVGKSTLVNRLLGEDRVVVFDMPGTTRDSIYIPYTREGKDYVLIDTAGVRRRGK
IDEKVEKFSVIKTLQAIEDSNVTVIVIDAHEGIVDQDLHMIGYALDAGRALVVAINKWDGLTADQKNYIKIEMDRRFNFI
PYVKVHQISALHGTGVGNLYPSILRAYQSSMFEVSTNRLTQILQDAVTANPPPTVAGRRIKLRYAHIGGHNPPVIVIHGN
QTGSLPKSYQRYLENQFRQVFKLEGTPLNVVFKLNENPYANKSDTPTKAKTQQLRQRERNRAQKFTTKDKPRFTNKDKKR

Sequences:

>Translated_480_residues
MSIKPVVALIGRPNVGKSTLFNQFTKSRQALVADLSGLTRDRQYGDATYEDKAFIVVDTGGIGEADDGRGDIDDYMSEQS
YTAIHEADIIVFVVDARAGMIGADAEIGKFLHTLGKPVYVVANKVDGVHDSAPAEFYALGLGEPYPMAASHGRGVGNLLE
VLTADMPSQENVVEPRGLKLAIIGRPNVGKSTLVNRLLGEDRVVVFDMPGTTRDSIYIPYTREGKDYVLIDTAGVRRRGK
IDEKVEKFSVIKTLQAIEDSNVTVIVIDAHEGIVDQDLHMIGYALDAGRALVVAINKWDGLTADQKNYIKIEMDRRFNFI
PYVKVHQISALHGTGVGNLYPSILRAYQSSMFEVSTNRLTQILQDAVTANPPPTVAGRRIKLRYAHIGGHNPPVIVIHGN
QTGSLPKSYQRYLENQFRQVFKLEGTPLNVVFKLNENPYANKSDTPTKAKTQQLRQRERNRAQKFTTKDKPRFTNKDKKR
>Mature_479_residues
SIKPVVALIGRPNVGKSTLFNQFTKSRQALVADLSGLTRDRQYGDATYEDKAFIVVDTGGIGEADDGRGDIDDYMSEQSY
TAIHEADIIVFVVDARAGMIGADAEIGKFLHTLGKPVYVVANKVDGVHDSAPAEFYALGLGEPYPMAASHGRGVGNLLEV
LTADMPSQENVVEPRGLKLAIIGRPNVGKSTLVNRLLGEDRVVVFDMPGTTRDSIYIPYTREGKDYVLIDTAGVRRRGKI
DEKVEKFSVIKTLQAIEDSNVTVIVIDAHEGIVDQDLHMIGYALDAGRALVVAINKWDGLTADQKNYIKIEMDRRFNFIP
YVKVHQISALHGTGVGNLYPSILRAYQSSMFEVSTNRLTQILQDAVTANPPPTVAGRRIKLRYAHIGGHNPPVIVIHGNQ
TGSLPKSYQRYLENQFRQVFKLEGTPLNVVFKLNENPYANKSDTPTKAKTQQLRQRERNRAQKFTTKDKPRFTNKDKKR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=496, Percent_Identity=55.8467741935484, Blast_Score=533, Evalue=1e-152,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=36.9565217391304, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=225, Percent_Identity=24, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_PSYCK (Q1QD14)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_579923.1
- ProteinModelPortal:   Q1QD14
- SMR:   Q1QD14
- STRING:   Q1QD14
- GeneID:   4033542
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_0656
- NMPDR:   fig|335284.3.peg.19
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q1QD14
- ProtClustDB:   PRK00093
- BioCyc:   PCRY335284:PCRYO_0656-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 53224; Mature: 53093

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKPVVALIGRPNVGKSTLFNQFTKSRQALVADLSGLTRDRQYGDATYEDKAFIVVDTG
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECC
GIGEADDGRGDIDDYMSEQSYTAIHEADIIVFVVDARAGMIGADAEIGKFLHTLGKPVYV
CCCCCCCCCCCHHHHHCCCCCEEEEECCEEEEEEECCCCEECCCHHHHHHHHHHCCCEEE
VANKVDGVHDSAPAEFYALGLGEPYPMAASHGRGVGNLLEVLTADMPSQENVVEPRGLKL
EEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEE
AIIGRPNVGKSTLVNRLLGEDRVVVFDMPGTTRDSIYIPYTREGKDYVLIDTAGVRRRGK
EEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCCC
IDEKVEKFSVIKTLQAIEDSNVTVIVIDAHEGIVDQDLHMIGYALDAGRALVVAINKWDG
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHEEEECCCCEEEEEEECCCC
LTADQKNYIKIEMDRRFNFIPYVKVHQISALHGTGVGNLYPSILRAYQSSMFEVSTNRLT
CCCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QILQDAVTANPPPTVAGRRIKLRYAHIGGHNPPVIVIHGNQTGSLPKSYQRYLENQFRQV
HHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
FKLEGTPLNVVFKLNENPYANKSDTPTKAKTQQLRQRERNRAQKFTTKDKPRFTNKDKKR
HCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIKPVVALIGRPNVGKSTLFNQFTKSRQALVADLSGLTRDRQYGDATYEDKAFIVVDTG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECC
GIGEADDGRGDIDDYMSEQSYTAIHEADIIVFVVDARAGMIGADAEIGKFLHTLGKPVYV
CCCCCCCCCCCHHHHHCCCCCEEEEECCEEEEEEECCCCEECCCHHHHHHHHHHCCCEEE
VANKVDGVHDSAPAEFYALGLGEPYPMAASHGRGVGNLLEVLTADMPSQENVVEPRGLKL
EEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEE
AIIGRPNVGKSTLVNRLLGEDRVVVFDMPGTTRDSIYIPYTREGKDYVLIDTAGVRRRGK
EEEECCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCCCCC
IDEKVEKFSVIKTLQAIEDSNVTVIVIDAHEGIVDQDLHMIGYALDAGRALVVAINKWDG
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHEEEECCCCEEEEEEECCCC
LTADQKNYIKIEMDRRFNFIPYVKVHQISALHGTGVGNLYPSILRAYQSSMFEVSTNRLT
CCCCCCCEEEEEECCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QILQDAVTANPPPTVAGRRIKLRYAHIGGHNPPVIVIHGNQTGSLPKSYQRYLENQFRQV
HHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHH
FKLEGTPLNVVFKLNENPYANKSDTPTKAKTQQLRQRERNRAQKFTTKDKPRFTNKDKKR
HCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA