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The map label for this gene is fabD [H]

Identifier: 93005345

GI number: 93005345

Start: 610479

End: 611447

Strand: Direct

Name: fabD [H]

Synonym: Pcryo_0515

Alternate gene names: 93005345

Gene position: 610479-611447 (Clockwise)

Preceding gene: 93005344

Following gene: 93005346

Centisome position: 19.95

GC content: 44.27

Gene sequence:

>969_bases
ATGGGCTCTGTACCCGATATGATAAAAAAACAACCAACCCGTATTGCAATACTGTTTCCTGGGCAAGGCTCACAAGTAGT
CGGTATGACAAGCGAGCTTGCTGATACCTATCCTGAAATTCTTGAAACCTTTACTGAAGCAAGTGCGGCATTAGGCGAAG
ATTTGTGGGCAATCTGTCAAGATGAAGAAAAACTTAATCAAACGCACTATACACAGCCTGCGTTATTGACCGCTAGTATC
GCTATTTGGCGCATCTTACAACAAAAAATAAAGGATAAGCCTTGTTACCTAGCTGGTCATTCTCTTGGCGAATATAGCGC
CCTTTGCGCAGCTAACGTGCTGTCACTTGCTGATGCCGTGAAACTGGTACATAAGCGTGGTCAATTGATGCAAGACGCTG
TAGTGGGTATTGATACGGCTATGGCAGCAGTACTGGGTTTGGAAGATCACCGAGTCGAAAATCTGTGTGAGCAAGCAACC
GAGCATGTAGATGATGCGATTGTTGGTGCAGCAAATTTTAATAGCCCAGGGCAAGTTGTGGTTTCTGGTAATGCTGCAGG
CGTTAATGCAGTCATTGATAAAGTACAAAATACGGGTAAAAAAGCCATTCCATTAAAGGTAAGTGTGCCGTCACATTGCG
CTTTGATGGAGCCTGCTAGTAAAGCGTTGGCAGCAGAGCTTGCCGCCATTAAGTTTGATCAAGCAACGATTCCTGTGATT
CAAAACCGTCATGCACGTGTTGAAACCAGTGCGGCAGGTATCAAAGAGGCGTTAACTGAACAATTAAGTCAGCCAGTATT
GTGGTCAAAAACCATGCAAGAGCTGGCAGATAAACAAATTAATATTTTAATTGAGTGTGGTAGTGGTAACGTCTTGAGTA
ATTTGGCGAAGCGTCAAGCGCATCCAATTATGAGCTATCCGACTGACAAGCCCGCTCGTCTAGATAAATTGCTGGAGGTA
TTATCATGA

Upstream 100 bases:

>100_bases
GTAACGGCTCTATAAAATTAATATCCTATTATAGTCTTTAACTCTACGATTAGCCCCATTTACGCTAGGGGTGTTTCCAA
TCAAATAAGGAATATTGGTT

Downstream 100 bases:

>100_bases
GCCGTACGATCACATTAGTCACAGGCGCAAGCCGCGGTATCGGCAAAGCCGTCGCCAAACGCTTTGCTAAGGAAGGACAT
TTTGTCATTGGGACAGCCAC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MGSVPDMIKKQPTRIAILFPGQGSQVVGMTSELADTYPEILETFTEASAALGEDLWAICQDEEKLNQTHYTQPALLTASI
AIWRILQQKIKDKPCYLAGHSLGEYSALCAANVLSLADAVKLVHKRGQLMQDAVVGIDTAMAAVLGLEDHRVENLCEQAT
EHVDDAIVGAANFNSPGQVVVSGNAAGVNAVIDKVQNTGKKAIPLKVSVPSHCALMEPASKALAAELAAIKFDQATIPVI
QNRHARVETSAAGIKEALTEQLSQPVLWSKTMQELADKQINILIECGSGNVLSNLAKRQAHPIMSYPTDKPARLDKLLEV
LS

Sequences:

>Translated_322_residues
MGSVPDMIKKQPTRIAILFPGQGSQVVGMTSELADTYPEILETFTEASAALGEDLWAICQDEEKLNQTHYTQPALLTASI
AIWRILQQKIKDKPCYLAGHSLGEYSALCAANVLSLADAVKLVHKRGQLMQDAVVGIDTAMAAVLGLEDHRVENLCEQAT
EHVDDAIVGAANFNSPGQVVVSGNAAGVNAVIDKVQNTGKKAIPLKVSVPSHCALMEPASKALAAELAAIKFDQATIPVI
QNRHARVETSAAGIKEALTEQLSQPVLWSKTMQELADKQINILIECGSGNVLSNLAKRQAHPIMSYPTDKPARLDKLLEV
LS
>Mature_321_residues
GSVPDMIKKQPTRIAILFPGQGSQVVGMTSELADTYPEILETFTEASAALGEDLWAICQDEEKLNQTHYTQPALLTASIA
IWRILQQKIKDKPCYLAGHSLGEYSALCAANVLSLADAVKLVHKRGQLMQDAVVGIDTAMAAVLGLEDHRVENLCEQATE
HVDDAIVGAANFNSPGQVVVSGNAAGVNAVIDKVQNTGKKAIPLKVSVPSHCALMEPASKALAAELAAIKFDQATIPVIQ
NRHARVETSAAGIKEALTEQLSQPVLWSKTMQELADKQINILIECGSGNVLSNLAKRQAHPIMSYPTDKPARLDKLLEVL
S

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=305, Percent_Identity=29.5081967213115, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1787334, Length=311, Percent_Identity=47.588424437299, Blast_Score=275, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=30.0341296928328, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=335, Percent_Identity=25.9701492537313, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=30.8724832214765, Blast_Score=111, Evalue=6e-25,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34517; Mature: 34386

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVPDMIKKQPTRIAILFPGQGSQVVGMTSELADTYPEILETFTEASAALGEDLWAICQ
CCCCCHHHHCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEEKLNQTHYTQPALLTASIAIWRILQQKIKDKPCYLAGHSLGEYSALCAANVLSLADAV
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
KLVHKRGQLMQDAVVGIDTAMAAVLGLEDHRVENLCEQATEHVDDAIVGAANFNSPGQVV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
VSGNAAGVNAVIDKVQNTGKKAIPLKVSVPSHCALMEPASKALAAELAAIKFDQATIPVI
EECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHCHHHHHHHHHHHHHHCCCCCCCHH
QNRHARVETSAAGIKEALTEQLSQPVLWSKTMQELADKQINILIECGSGNVLSNLAKRQA
HCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHC
HPIMSYPTDKPARLDKLLEVLS
CCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
GSVPDMIKKQPTRIAILFPGQGSQVVGMTSELADTYPEILETFTEASAALGEDLWAICQ
CCCCHHHHCCCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEEKLNQTHYTQPALLTASIAIWRILQQKIKDKPCYLAGHSLGEYSALCAANVLSLADAV
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
KLVHKRGQLMQDAVVGIDTAMAAVLGLEDHRVENLCEQATEHVDDAIVGAANFNSPGQVV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEE
VSGNAAGVNAVIDKVQNTGKKAIPLKVSVPSHCALMEPASKALAAELAAIKFDQATIPVI
EECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHCHHHHHHHHHHHHHHCCCCCCCHH
QNRHARVETSAAGIKEALTEQLSQPVLWSKTMQELADKQINILIECGSGNVLSNLAKRQA
HCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHC
HPIMSYPTDKPARLDKLLEVLS
CCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]