Click here to switch to the map view.

The map label for this gene is omp38 [H]

Identifier: 93005202

GI number: 93005202

Start: 450611

End: 451789

Strand: Direct

Name: omp38 [H]

Synonym: Pcryo_0372

Alternate gene names: 93005202

Gene position: 450611-451789 (Clockwise)

Preceding gene: 93005200

Following gene: 93005203

Centisome position: 14.73

GC content: 42.66

Gene sequence:

>1179_bases
ATGAAATTAAATAAAATTGCTTTGGCTTTGTTTGCCATCACAGCAGCCCCACTAGCAGCTAACGCTGGCGTAACTATCAG
CCCATTATTACTTGGTTATCATTACAGCGAAGGTGCTGACGATGAGCAAGCTGAAATCATGGGTGATGGTAATGGAAATG
GCTTCTATCAAGAGAACGGTCTATATACTGGTGCTGCACTAGGTATTGAAATTACTCCTTCTACTCAGTTCCAAGTAGAA
TATGGTGTATCAAATACTGATGCCGTTCGTCAAGATGGAAATACTGACTTTGATGCAGAACAAGAAACTATCTCTGGTAA
CTTCTTGATCGGTACTGAGCAATTCACTGGTTATACTGATAGTGCATTAAAGCCATATGTATTAGTTGGTGCTGGTCGCT
CTAAGATTGAAGTTGAAGATGCTGCTGGTAACTTCGTTACTGGTTCTAAAGATACTATCGGTAACCTAGGTCTAGGTGCT
ATGTACCGTATTAACGACGCTTTAAGCCTACGTGGTGAAGCTCGTGCGATTCATAACTTTGATAACAACTGGTGGGAAGG
CATGGCTTTGGCCGGTCTAGAAGTAGTACTAGGTGGTCACTTAGCACCAGCAGTAGCTGTTCCACCGATGCAAGAGCCTA
ACGTTCAGACTCCACCAATCGTTGTTGTTGAATCTGATCTTGATTCAGACGGCGATGGCGTACCTGATAGCATCGATGCT
TGCCCAGGCACTCCAATGAATGTTGTTGTAGATGAGCGCGGTTGCCCAGTACCAGTAGATATTACTGATGAATTGAAAAT
GGAACTACGTGTATTCTTTGATAACGATAAATCAGCTATCAAAACTCAGTACAAACCTGAAATCGCTAAAGTAGCAGAGA
AGATGCGCGAGTATCCTAACTCTACCGCTCGTGTTGAAGGTCATGCTTCTAAAACTGGTCCATCAGCACGTTATAACCAA
CGTTTGTCTGAAGCCCGTGCTGTTGCTGTGAAATCTATGTTGACTAACGAATTTGGTATTGCTCCAAACCGTCTATCAAC
CGTTGGTTATGGTTATGATCAACCAATCGCTGACAACAACACTGAAGAAGGTCGTGCTATGAACCGTCGTGTTTATGCCA
TCATCACTGGTGACAAAACAATGACTGTTGAACAAACTAAAGATATGGTTGTTCAATAA

Upstream 100 bases:

>100_bases
ATTGGTTTTGCTTTGTAATTTTAAGTTCGTAAATGATGTTTGTTTTTGAGCAATAGTTTTGCTTAATGCACTACTAAAAT
TATCCTTTGGAGGAAGTTTC

Downstream 100 bases:

>100_bases
GTACTAGCTACTAATTGTGTAATAAGCTAATTAGTTACAAAAAAAGTCATCCAATGGGTGGCTTTTTTTTATTTATGTAT
CGAGAAAAGTAAGTTATTAC

Product: OmpA/MotB

Products: NA

Alternate protein names: Outer membrane protein ompA; Outer membrane protein ompAb [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKLNKIALALFAITAAPLAANAGVTISPLLLGYHYSEGADDEQAEIMGDGNGNGFYQENGLYTGAALGIEITPSTQFQVE
YGVSNTDAVRQDGNTDFDAEQETISGNFLIGTEQFTGYTDSALKPYVLVGAGRSKIEVEDAAGNFVTGSKDTIGNLGLGA
MYRINDALSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVAVPPMQEPNVQTPPIVVVESDLDSDGDGVPDSIDA
CPGTPMNVVVDERGCPVPVDITDELKMELRVFFDNDKSAIKTQYKPEIAKVAEKMREYPNSTARVEGHASKTGPSARYNQ
RLSEARAVAVKSMLTNEFGIAPNRLSTVGYGYDQPIADNNTEEGRAMNRRVYAIITGDKTMTVEQTKDMVVQ

Sequences:

>Translated_392_residues
MKLNKIALALFAITAAPLAANAGVTISPLLLGYHYSEGADDEQAEIMGDGNGNGFYQENGLYTGAALGIEITPSTQFQVE
YGVSNTDAVRQDGNTDFDAEQETISGNFLIGTEQFTGYTDSALKPYVLVGAGRSKIEVEDAAGNFVTGSKDTIGNLGLGA
MYRINDALSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVAVPPMQEPNVQTPPIVVVESDLDSDGDGVPDSIDA
CPGTPMNVVVDERGCPVPVDITDELKMELRVFFDNDKSAIKTQYKPEIAKVAEKMREYPNSTARVEGHASKTGPSARYNQ
RLSEARAVAVKSMLTNEFGIAPNRLSTVGYGYDQPIADNNTEEGRAMNRRVYAIITGDKTMTVEQTKDMVVQ
>Mature_392_residues
MKLNKIALALFAITAAPLAANAGVTISPLLLGYHYSEGADDEQAEIMGDGNGNGFYQENGLYTGAALGIEITPSTQFQVE
YGVSNTDAVRQDGNTDFDAEQETISGNFLIGTEQFTGYTDSALKPYVLVGAGRSKIEVEDAAGNFVTGSKDTIGNLGLGA
MYRINDALSLRGEARAIHNFDNNWWEGMALAGLEVVLGGHLAPAVAVPPMQEPNVQTPPIVVVESDLDSDGDGVPDSIDA
CPGTPMNVVVDERGCPVPVDITDELKMELRVFFDNDKSAIKTQYKPEIAKVAEKMREYPNSTARVEGHASKTGPSARYNQ
RLSEARAVAVKSMLTNEFGIAPNRLSTVGYGYDQPIADNNTEEGRAMNRRVYAIITGDKTMTVEQTKDMVVQ

Specific function: Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochr

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=122, Percent_Identity=36.8852459016393, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 42098; Mature: 42098

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNKIALALFAITAAPLAANAGVTISPLLLGYHYSEGADDEQAEIMGDGNGNGFYQENG
CCCHHHHHHHHHHHHCCHHCCCCCEEEEEEEEEECCCCCCCCCEEEEECCCCCCEEECCC
LYTGAALGIEITPSTQFQVEYGVSNTDAVRQDGNTDFDAEQETISGNFLIGTEQFTGYTD
EEEEEEEEEEECCCCEEEEEECCCCCHHHHCCCCCCCCCCHHCCCCCEEEECHHHCCCCC
SALKPYVLVGAGRSKIEVEDAAGNFVTGSKDTIGNLGLGAMYRINDALSLRGEARAIHNF
CCCCCEEEEECCCCEEEEECCCCCEECCCCCCCCCCCCCEEEEECHHHHCCCCHHEEECC
DNNWWEGMALAGLEVVLGGHLAPAVAVPPMQEPNVQTPPIVVVESDLDSDGDGVPDSIDA
CCCHHCCCHHHCEEEEECCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
CPGTPMNVVVDERGCPVPVDITDELKMELRVFFDNDKSAIKTQYKPEIAKVAEKMREYPN
CCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHCCC
STARVEGHASKTGPSARYNQRLSEARAVAVKSMLTNEFGIAPNRLSTVGYGYDQPIADNN
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCC
TEEGRAMNRRVYAIITGDKTMTVEQTKDMVVQ
CCCCHHCCCEEEEEEECCCEEEEECCHHHHCC
>Mature Secondary Structure
MKLNKIALALFAITAAPLAANAGVTISPLLLGYHYSEGADDEQAEIMGDGNGNGFYQENG
CCCHHHHHHHHHHHHCCHHCCCCCEEEEEEEEEECCCCCCCCCEEEEECCCCCCEEECCC
LYTGAALGIEITPSTQFQVEYGVSNTDAVRQDGNTDFDAEQETISGNFLIGTEQFTGYTD
EEEEEEEEEEECCCCEEEEEECCCCCHHHHCCCCCCCCCCHHCCCCCEEEECHHHCCCCC
SALKPYVLVGAGRSKIEVEDAAGNFVTGSKDTIGNLGLGAMYRINDALSLRGEARAIHNF
CCCCCEEEEECCCCEEEEECCCCCEECCCCCCCCCCCCCEEEEECHHHHCCCCHHEEECC
DNNWWEGMALAGLEVVLGGHLAPAVAVPPMQEPNVQTPPIVVVESDLDSDGDGVPDSIDA
CCCHHCCCHHHCEEEEECCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
CPGTPMNVVVDERGCPVPVDITDELKMELRVFFDNDKSAIKTQYKPEIAKVAEKMREYPN
CCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHCCC
STARVEGHASKTGPSARYNQRLSEARAVAVKSMLTNEFGIAPNRLSTVGYGYDQPIADNN
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCC
TEEGRAMNRRVYAIITGDKTMTVEQTKDMVVQ
CCCCHHCCCEEEEEEECCCEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA