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The map label for this gene is gcp

Identifier: 93005065

GI number: 93005065

Start: 276838

End: 277896

Strand: Direct

Name: gcp

Synonym: Pcryo_0234

Alternate gene names: 93005065

Gene position: 276838-277896 (Clockwise)

Preceding gene: 93005064

Following gene: 93005066

Centisome position: 9.05

GC content: 47.88

Gene sequence:

>1059_bases
ATGAAAGTATTGGGATTAGAAACCTCTTGCGATGAGACGGGTCTAGCGATTTTTGATAGCGAACAGGTAACGAGCGACAA
TAAAGGTCTACTTGGGCAAGTATTGTATTCACAAATAGAGCTGCACGCCCTTTATGGCGGCGTGGTGCCTGAGCTTGCTA
GTCGCGATCATATCCGTAAGTTAGTGCCTTTATTTAATGAGCTTTTGCAGCAATGCAATATCACTAAAGATGAGATTGAT
GCCGTCGCTTATACCAAGGGTCCGGGGCTTATCGGCGCCTTGATGACAGGTGCATTGTTTGGTCGTAGCTTGGCTTATGG
GTTAGATATTCCAGCGATTGGTGTTCATCATATGGAAGGGCATCTATTGGCACCGCTGATGGGTGCGAATCCACCAGCGT
TTCCGTTTGTCTCCTTACTTGTTTCTGGTGGGCATACGCTACTCATTGCTGCGCATGGTATTGGTCAATATGAAATCCTT
GGCGAATCCATTGATGATGCGGCAGGTGAGTGTTTTGACAAAGCGGCGAAGATGTTGGGCTTGCCATATCCGGGTGGTCC
TAATATCGCTAAATTAGCGGAAAGTGGTAATTCGGACGCTTATAGTTTACCAAGACCAATGTTACATCGTGGTTTGGATT
TCTCTTTTAGCGGTATGAAAACAGCCGTACATAATCTTATCAAGGACACCCCATGCTCAGGGGGTTCAGGAAATGGCTCT
GATAGCGACCCGCAAGTCCGTGCTGATATTGCCGCCAGTTTTCAGCATGCCGTGGTCGATACCTTGGTGAAAAAATGCGT
CAAAGCGCTTAAGCAAGTGAATATGAGCCGATTGGTTATCGCAGGCGGTGTCAGTGCCAATAGTCATTTGCGTAAAACTC
TCGAGCGGGAGCTTGCTAAGATAAATGCGACCGTACATTATGCACCTCCTGCTTTATGTACCGATAATGGTGCGATGATT
GCGTATGCGGGCTACGAGCGTTTGCAAGCGGGTCAAGCAGATGATTTGGCTGTCAGCTGCGTGCCACGTTGGCCAATGAC
CGAGTTGCCAGCGGTATAA

Upstream 100 bases:

>100_bases
CTAAATATTATTGATTGAAATTTGCTAAACTGACCGTCATTGTAAGCTTACAGTGGCGGTTTTTTATTCACGCTACAAGG
CAAAATATAAAGGCACATAG

Downstream 100 bases:

>100_bases
GCGCTAGAAAGTCGCTTGTATCCAATTTATTAAACTTTATATCACTCAAGGATAACTTATGCAGTGGCTTGCGATTGGAT
TAGGTGCTGCCATTGGCGCT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKVLGLETSCDETGLAIFDSEQVTSDNKGLLGQVLYSQIELHALYGGVVPELASRDHIRKLVPLFNELLQQCNITKDEID
AVAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGVHHMEGHLLAPLMGANPPAFPFVSLLVSGGHTLLIAAHGIGQYEIL
GESIDDAAGECFDKAAKMLGLPYPGGPNIAKLAESGNSDAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTPCSGGSGNGS
DSDPQVRADIAASFQHAVVDTLVKKCVKALKQVNMSRLVIAGGVSANSHLRKTLERELAKINATVHYAPPALCTDNGAMI
AYAGYERLQAGQADDLAVSCVPRWPMTELPAV

Sequences:

>Translated_352_residues
MKVLGLETSCDETGLAIFDSEQVTSDNKGLLGQVLYSQIELHALYGGVVPELASRDHIRKLVPLFNELLQQCNITKDEID
AVAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGVHHMEGHLLAPLMGANPPAFPFVSLLVSGGHTLLIAAHGIGQYEIL
GESIDDAAGECFDKAAKMLGLPYPGGPNIAKLAESGNSDAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTPCSGGSGNGS
DSDPQVRADIAASFQHAVVDTLVKKCVKALKQVNMSRLVIAGGVSANSHLRKTLERELAKINATVHYAPPALCTDNGAMI
AYAGYERLQAGQADDLAVSCVPRWPMTELPAV
>Mature_352_residues
MKVLGLETSCDETGLAIFDSEQVTSDNKGLLGQVLYSQIELHALYGGVVPELASRDHIRKLVPLFNELLQQCNITKDEID
AVAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGVHHMEGHLLAPLMGANPPAFPFVSLLVSGGHTLLIAAHGIGQYEIL
GESIDDAAGECFDKAAKMLGLPYPGGPNIAKLAESGNSDAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTPCSGGSGNGS
DSDPQVRADIAASFQHAVVDTLVKKCVKALKQVNMSRLVIAGGVSANSHLRKTLERELAKINATVHYAPPALCTDNGAMI
AYAGYERLQAGQADDLAVSCVPRWPMTELPAV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=345, Percent_Identity=36.8115942028986, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI8923380, Length=351, Percent_Identity=29.6296296296296, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1789445, Length=352, Percent_Identity=61.6477272727273, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17557464, Length=338, Percent_Identity=30.1775147928994, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71995670, Length=341, Percent_Identity=32.8445747800587, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320099, Length=380, Percent_Identity=36.0526315789474, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322891, Length=298, Percent_Identity=30.2013422818792, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI20129063, Length=346, Percent_Identity=32.9479768786127, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21357207, Length=340, Percent_Identity=29.7058823529412, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_PSYCK (Q1QE85)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_579502.1
- ProteinModelPortal:   Q1QE85
- SMR:   Q1QE85
- STRING:   Q1QE85
- MEROPS:   M22.001
- GeneID:   4035426
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_0234
- NMPDR:   fig|335284.3.peg.923
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   Q1QE85
- ProtClustDB:   PRK09604
- BioCyc:   PCRY335284:PCRYO_0234-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37196; Mature: 37196

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGLETSCDETGLAIFDSEQVTSDNKGLLGQVLYSQIELHALYGGVVPELASRDHIRK
CEEECCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVPLFNELLQQCNITKDEIDAVAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGVHHMEG
HHHHHHHHHHHCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HLLAPLMGANPPAFPFVSLLVSGGHTLLIAAHGIGQYEILGESIDDAAGECFDKAAKMLG
CEECHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHC
LPYPGGPNIAKLAESGNSDAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTPCSGGSGNGS
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DSDPQVRADIAASFQHAVVDTLVKKCVKALKQVNMSRLVIAGGVSANSHLRKTLERELAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHHHH
INATVHYAPPALCTDNGAMIAYAGYERLQAGQADDLAVSCVPRWPMTELPAV
HCCEEEECCCCEECCCCCEEEECCHHHHHCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKVLGLETSCDETGLAIFDSEQVTSDNKGLLGQVLYSQIELHALYGGVVPELASRDHIRK
CEEECCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LVPLFNELLQQCNITKDEIDAVAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGVHHMEG
HHHHHHHHHHHCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
HLLAPLMGANPPAFPFVSLLVSGGHTLLIAAHGIGQYEILGESIDDAAGECFDKAAKMLG
CEECHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHC
LPYPGGPNIAKLAESGNSDAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTPCSGGSGNGS
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DSDPQVRADIAASFQHAVVDTLVKKCVKALKQVNMSRLVIAGGVSANSHLRKTLERELAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCHHHHHHHHHHHHHH
INATVHYAPPALCTDNGAMIAYAGYERLQAGQADDLAVSCVPRWPMTELPAV
HCCEEEECCCCEECCCCCEEEECCHHHHHCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA