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The map label for this gene is sucC [H]

Identifier: 93004945

GI number: 93004945

Start: 135235

End: 136401

Strand: Direct

Name: sucC [H]

Synonym: Pcryo_0114

Alternate gene names: 93004945

Gene position: 135235-136401 (Clockwise)

Preceding gene: 93004944

Following gene: 93004946

Centisome position: 4.42

GC content: 44.13

Gene sequence:

>1167_bases
ATGAATTTACATGAGTATCAAGCAAAAGAGCTATTGAAAAGCTACGGCTTGCCAATTCAAGAAGGCATCATTGCTTACAG
TGGCGACGAAGCAGCGGCAGCTTTTGACAAAACCCCAACTGATATCGCAGTCATCAAAGCGCAGGTTCATGCTGGTGGTC
GCGGTAAAGCGGGCGGCGTGAAACTGGTTAAGACTCGTGAAGAAGCGAAGCAAGTGACTGATGAGCTTATCGGTAAAAAC
CTTGTAACGTATCAAACCGATGCCGCTGGTCAACCAGTGAATTTCGTTTTGGTTGCAGAAGATATGTATCCAGTGCAAAC
CGAGCTATATCTTGGCGCTGTTGTTGACCGCTCTTCACGTCGCGTGACGTTTATGGCATCAACGGAAGGCGGTGTTGAGA
TTGAGAAAGTTGCAGAAGAAACGCCAGAGAAAATCTTTAAAGTAAATATTGATCCATTGGTTGGTTTATTGCCATTCCAA
GCGCGTGAAGTCGCGTTTAAATTGGGTCTTGAAGGCAAGCAAATCAATCAATTCGTTAAATTGATGTCTGGTGCTTATCA
AGCATTCGTTGAAAACGACATTGATTTACTTGAAATCAACCCATTAGCGGTTCGCGAAAATGGCGAGATCGTTTGTGTTG
ATGGCAAAATTGGTATTGACTCAAACGCTTTATATCGTTTGCCTAAGATTGCTGCGCTACAAGACAAATCACAAGAAAAT
GAGCGTGAGCTTAAAGCGGCTGAGTTTGATCTAAACTATGTTGCCCTAGAAGGCAATATCGGTTGTATGGTAAACGGTGC
TGGTCTTGCAATGGCTACGATGGACATCATCAAATTGTACGGCGGCAAGCCTGCTAACTTCTTGGACGTTGGCGGCGGTG
CAACTAAAGATCGCGTTGTTGAAGCCTTCAAGATCATTCTTGAAGACAGCAGCGTTGAAGGTGTTCTGATCAACATCTTC
GGTGGTATCGTACGTTGTGACATGATTGCAGAAGCTATTATCGCTGCGATCAAAGAAGTTGACGTCAAAGTACCAGTTGT
TGTCCGTTTAGAGGGTAACAATGCTGAGCTTGGCGCACAAATTCTAGAAGAATCTGGTCTGAAATTGATCTCAGCTCAAG
GTTTATCAGACGCCGCTCAAAAAATTGTTGACGCTGTTAAAGCTTAA

Upstream 100 bases:

>100_bases
TAGCTATTTTGAATGCTGCGTTGGTCTAACATACAGTAGAGCATTCTACGATGTATGAGTTTTCATTTTTTATTAATGGT
AAAAATAAAGGATTCAATCA

Downstream 100 bases:

>100_bases
TTGCTCAAGAGTATAAGGCGTTTGCTGTTATTCTACCGACGTTAACATTTAACGTGGCAGGATAGGCAAGCGCCTACCAG
ACAACCGCATACAAGGATAA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKELLKSYGLPIQEGIIAYSGDEAAAAFDKTPTDIAVIKAQVHAGGRGKAGGVKLVKTREEAKQVTDELIGKN
LVTYQTDAAGQPVNFVLVAEDMYPVQTELYLGAVVDRSSRRVTFMASTEGGVEIEKVAEETPEKIFKVNIDPLVGLLPFQ
AREVAFKLGLEGKQINQFVKLMSGAYQAFVENDIDLLEINPLAVRENGEIVCVDGKIGIDSNALYRLPKIAALQDKSQEN
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVVEAFKIILEDSSVEGVLINIF
GGIVRCDMIAEAIIAAIKEVDVKVPVVVRLEGNNAELGAQILEESGLKLISAQGLSDAAQKIVDAVKA

Sequences:

>Translated_388_residues
MNLHEYQAKELLKSYGLPIQEGIIAYSGDEAAAAFDKTPTDIAVIKAQVHAGGRGKAGGVKLVKTREEAKQVTDELIGKN
LVTYQTDAAGQPVNFVLVAEDMYPVQTELYLGAVVDRSSRRVTFMASTEGGVEIEKVAEETPEKIFKVNIDPLVGLLPFQ
AREVAFKLGLEGKQINQFVKLMSGAYQAFVENDIDLLEINPLAVRENGEIVCVDGKIGIDSNALYRLPKIAALQDKSQEN
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVVEAFKIILEDSSVEGVLINIF
GGIVRCDMIAEAIIAAIKEVDVKVPVVVRLEGNNAELGAQILEESGLKLISAQGLSDAAQKIVDAVKA
>Mature_388_residues
MNLHEYQAKELLKSYGLPIQEGIIAYSGDEAAAAFDKTPTDIAVIKAQVHAGGRGKAGGVKLVKTREEAKQVTDELIGKN
LVTYQTDAAGQPVNFVLVAEDMYPVQTELYLGAVVDRSSRRVTFMASTEGGVEIEKVAEETPEKIFKVNIDPLVGLLPFQ
AREVAFKLGLEGKQINQFVKLMSGAYQAFVENDIDLLEINPLAVRENGEIVCVDGKIGIDSNALYRLPKIAALQDKSQEN
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVVEAFKIILEDSSVEGVLINIF
GGIVRCDMIAEAIIAAIKEVDVKVPVVVRLEGNNAELGAQILEESGLKLISAQGLSDAAQKIVDAVKA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=47.4358974358974, Blast_Score=345, Evalue=6e-95,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=44.2708333333333, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=44.3526170798898, Blast_Score=286, Evalue=2e-77,
Organism=Escherichia coli, GI1786948, Length=387, Percent_Identity=63.3074935400517, Blast_Score=482, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=43.5443037974684, Blast_Score=321, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=44.2159383033419, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6321683, Length=394, Percent_Identity=43.4010152284264, Blast_Score=331, Evalue=1e-91,
Organism=Drosophila melanogaster, GI161078106, Length=386, Percent_Identity=44.559585492228, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24645208, Length=386, Percent_Identity=44.559585492228, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI281361397, Length=387, Percent_Identity=44.702842377261, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI281361395, Length=387, Percent_Identity=44.702842377261, Blast_Score=305, Evalue=3e-83,
Organism=Drosophila melanogaster, GI21356231, Length=399, Percent_Identity=43.859649122807, Blast_Score=299, Evalue=3e-81,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41667; Mature: 41667

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKELLKSYGLPIQEGIIAYSGDEAAAAFDKTPTDIAVIKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCHHHCEEEECCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCE
KLVKTREEAKQVTDELIGKNLVTYQTDAAGQPVNFVLVAEDMYPVQTELYLGAVVDRSSR
EEEECHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCHHHEEEEEEEECCCC
RVTFMASTEGGVEIEKVAEETPEKIFKVNIDPLVGLLPFQAREVAFKLGLEGKQINQFVK
EEEEEEECCCCCCHHHHHHCCCHHEEEEECCHHHCCCCCHHHHHHHEECCCHHHHHHHHH
LMSGAYQAFVENDIDLLEINPLAVRENGEIVCVDGKIGIDSNALYRLPKIAALQDKSQEN
HHHHHHHHHHCCCCCEEEECCEEEECCCCEEEECCCCCCCCCHHCCCCCHHHHCCCCCCH
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVV
HHHHHHEEECEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHH
EAFKIILEDSSVEGVLINIFGGIVRCDMIAEAIIAAIKEVDVKVPVVVRLEGNNAELGAQ
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
ILEESGLKLISAQGLSDAAQKIVDAVKA
HHHHCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKELLKSYGLPIQEGIIAYSGDEAAAAFDKTPTDIAVIKAQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCHHHCEEEECCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCE
KLVKTREEAKQVTDELIGKNLVTYQTDAAGQPVNFVLVAEDMYPVQTELYLGAVVDRSSR
EEEECHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCHHHEEEEEEEECCCC
RVTFMASTEGGVEIEKVAEETPEKIFKVNIDPLVGLLPFQAREVAFKLGLEGKQINQFVK
EEEEEEECCCCCCHHHHHHCCCHHEEEEECCHHHCCCCCHHHHHHHEECCCHHHHHHHHH
LMSGAYQAFVENDIDLLEINPLAVRENGEIVCVDGKIGIDSNALYRLPKIAALQDKSQEN
HHHHHHHHHHCCCCCEEEECCEEEECCCCEEEECCCCCCCCCHHCCCCCHHHHCCCCCCH
ERELKAAEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGKPANFLDVGGGATKDRVV
HHHHHHEEECEEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHH
EAFKIILEDSSVEGVLINIFGGIVRCDMIAEAIIAAIKEVDVKVPVVVRLEGNNAELGAQ
HHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHH
ILEESGLKLISAQGLSDAAQKIVDAVKA
HHHHCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA