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The map label for this gene is qor [C]

Identifier: 93004918

GI number: 93004918

Start: 100240

End: 101235

Strand: Direct

Name: qor [C]

Synonym: Pcryo_0087

Alternate gene names: 93004918

Gene position: 100240-101235 (Clockwise)

Preceding gene: 93004917

Following gene: 93004922

Centisome position: 3.28

GC content: 42.77

Gene sequence:

>996_bases
ATGTCTGATAAAAGCATGCCAATGACTCAAAATGCCGTACTCATACGTGAGTTTGGTGAACCTGAAGTCATGATATACCA
AGATGATGTTGCCGTACCTGATTTGACAGATGATCAAGTGCTGGTAAAAGTTGCTTACGCCGGTATCAATCCAGTCGATT
ATAAAACTCGTCAAGGTAAAGGCTGGGGCGCTACCAACATCCAAAAAGATAAGTTTGATCATAATCAACCAGCGATTTTG
GGTTTTGATATGTCAGGCACAGTAGTTGACAGTCAAAGTAAAAAATTTGCCGTTGGTGATAAAGTCGCAGCATTAACTTT
TAACGGTGGATGCTATGCTGAATATGTCGCTGTTGATGCTAAAATGCTGGCACGTGTACCTGAAGCTGTCACCTTAGAGC
AGGCAGGCGCATTACCTTGTATCGGACAAACGGCGCTACAGTTTGTTGAGTTTGCTGATATCAAAGAGGGCGAGCATGTA
GTGATGAATGCCCCAGCAGGCGGTGTTGGTCATCTATTGATACAGCTTTTGATGAAAAAAATCGCTAAACATAATATCAA
AGTCACGCTTATTTGTTCAGCAGAAAAGTATAAAAAACTGGATAGCTTGATAGATACTAATCAGCTTACAGGCTGGATTG
ACTACACCAAAAATGATTCGTTCCCTGAGCTGCAAGCCGACGTCTTATTGGATTTGGTCGGTGATGAAGCGGGTGTAAGG
GCGCTAGACGTTGTCAAAGAGTCTGGACGTGTATATGTACTACCAACAATTTGGGTAGATAAACTCAAAGGAGCAGGCAG
TCAAAAAAACCTAAGCGTTGAAGGTTATGCGGCTCAGCGTAATGGTGAGGATATGGCACGAGTGCTACAGCTGGTAGCAG
ATGGTCAACTGACTTTACGTTTGCAAAAGACTTATCCATTGTCAGAAGTCGTTATCGCCCATCATGAGCTGCAAAAAGGC
GATGCTTTTGGTAAATTGGTATTGAAAGTCAGTTGA

Upstream 100 bases:

>100_bases
CTGATCATCTGCCTTTGAGTGCAGAACTGGCGTTGCTATAGAGTAAAAATTATTAATGGAATAAAGAACGCTAAACTAAA
ATAAACAAGGATGATAAATA

Downstream 100 bases:

>100_bases
GCCGAGGTTGATTGGATAATAGATTTAGCTAATGGTTAGCTTCGATTATTTGGATATATTTGCCGAAAGGTTAGGCTAAT
GCGTCCTGTGGTTACCTTTT

Product: alcohol dehydrogenase GroES-like protein

Products: NADP(+); Semiquinone. [C]

Alternate protein names: Oxidoreductase; NADPHQuinone Reductase; Dehydrogenase; Alcohol Dehydrogenase GroES Domain Protein; Quinone Oxidoreductase; Alcohol Dehydrogenase GroES Domain-Containing Protein; Alcohol Dehydrogenase Zinc-Dependent; NADPH-Quinone Reductase; Zinc-Containing Alcohol Dehydrogenase Superfamily Protein; Zinc-Containing Alcohol Dehydrogenase; Alcohol Dehydrogenase GroES-Like Domain Family; NADPHQuinone Oxidoreductase; NAD(P)H Quinone Oxidoreductase PIG3 Family; Zn-Dependent Oxidoreductase NADPHQuinone Reductase; Alcohol Dehydrogenase Zinc-Containing; Zinc-Type Alcohol Dehydrogenase; NADPHQuinone Reductase Related Zn-Dependent Oxidoreductase; Alcohol Dehydrogenase GroES-Like Protein; Quinone Reductase; NADPH2Quinone Reductase; Alcohol Dehydrogenase Zinc Containing Protein; Zinc-Dependent Oxidoreductase; Oxydoreductase Protein Zinc-Containing; PIG3 Family NAD(P)H Quinone Oxidoreductase; Quinone Oxidoreductase-Like Protein; NAD-Dependent Alcohol Dehydrogenase; Ripening-Induced Protein- Zn-Containing Oxidoreductase; Zn-Dependent Oxidoreductase; Alcohol Dehydrogenase Zinc-Containing Protein; NADPH Quinone Oxidoreductase

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSDKSMPMTQNAVLIREFGEPEVMIYQDDVAVPDLTDDQVLVKVAYAGINPVDYKTRQGKGWGATNIQKDKFDHNQPAIL
GFDMSGTVVDSQSKKFAVGDKVAALTFNGGCYAEYVAVDAKMLARVPEAVTLEQAGALPCIGQTALQFVEFADIKEGEHV
VMNAPAGGVGHLLIQLLMKKIAKHNIKVTLICSAEKYKKLDSLIDTNQLTGWIDYTKNDSFPELQADVLLDLVGDEAGVR
ALDVVKESGRVYVLPTIWVDKLKGAGSQKNLSVEGYAAQRNGEDMARVLQLVADGQLTLRLQKTYPLSEVVIAHHELQKG
DAFGKLVLKVS

Sequences:

>Translated_331_residues
MSDKSMPMTQNAVLIREFGEPEVMIYQDDVAVPDLTDDQVLVKVAYAGINPVDYKTRQGKGWGATNIQKDKFDHNQPAIL
GFDMSGTVVDSQSKKFAVGDKVAALTFNGGCYAEYVAVDAKMLARVPEAVTLEQAGALPCIGQTALQFVEFADIKEGEHV
VMNAPAGGVGHLLIQLLMKKIAKHNIKVTLICSAEKYKKLDSLIDTNQLTGWIDYTKNDSFPELQADVLLDLVGDEAGVR
ALDVVKESGRVYVLPTIWVDKLKGAGSQKNLSVEGYAAQRNGEDMARVLQLVADGQLTLRLQKTYPLSEVVIAHHELQKG
DAFGKLVLKVS
>Mature_330_residues
SDKSMPMTQNAVLIREFGEPEVMIYQDDVAVPDLTDDQVLVKVAYAGINPVDYKTRQGKGWGATNIQKDKFDHNQPAILG
FDMSGTVVDSQSKKFAVGDKVAALTFNGGCYAEYVAVDAKMLARVPEAVTLEQAGALPCIGQTALQFVEFADIKEGEHVV
MNAPAGGVGHLLIQLLMKKIAKHNIKVTLICSAEKYKKLDSLIDTNQLTGWIDYTKNDSFPELQADVLLDLVGDEAGVRA
LDVVKESGRVYVLPTIWVDKLKGAGSQKNLSVEGYAAQRNGEDMARVLQLVADGQLTLRLQKTYPLSEVVIAHHELQKGD
AFGKLVLKVS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI47519420, Length=359, Percent_Identity=27.8551532033426, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI194239674, Length=334, Percent_Identity=26.9461077844311, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13236495, Length=334, Percent_Identity=26.9461077844311, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI194239676, Length=169, Percent_Identity=33.1360946745562, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI22538446, Length=172, Percent_Identity=34.3023255813954, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI22538444, Length=172, Percent_Identity=34.3023255813954, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI24308257, Length=235, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=179, Percent_Identity=33.5195530726257, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=356, Percent_Identity=28.0898876404494, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 36079; Mature: 35948

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKSMPMTQNAVLIREFGEPEVMIYQDDVAVPDLTDDQVLVKVAYAGINPVDYKTRQGK
CCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
GWGATNIQKDKFDHNQPAILGFDMSGTVVDSQSKKFAVGDKVAALTFNGGCYAEYVAVDA
CCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCEEEECCEEEEEEECCCCEEEHHHHHH
KMLARVPEAVTLEQAGALPCIGQTALQFVEFADIKEGEHVVMNAPAGGVGHLLIQLLMKK
HHHHHCCCCEEHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHH
IAKHNIKVTLICSAEKYKKLDSLIDTNQLTGWIDYTKNDSFPELQADVLLDLVGDEAGVR
HHHCCCEEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCH
ALDVVKESGRVYVLPTIWVDKLKGAGSQKNLSVEGYAAQRNGEDMARVLQLVADGQLTLR
HEEHHHHCCCEEEEEEEEEEHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEE
LQKTYPLSEVVIAHHELQKGDAFGKLVLKVS
EECCCCHHHHHHHHHHHHCCCCEEEEEEEEC
>Mature Secondary Structure 
SDKSMPMTQNAVLIREFGEPEVMIYQDDVAVPDLTDDQVLVKVAYAGINPVDYKTRQGK
CCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCC
GWGATNIQKDKFDHNQPAILGFDMSGTVVDSQSKKFAVGDKVAALTFNGGCYAEYVAVDA
CCCCCCCCCCCCCCCCCEEEEECCCCCEECCCCCEEEECCEEEEEEECCCCEEEHHHHHH
KMLARVPEAVTLEQAGALPCIGQTALQFVEFADIKEGEHVVMNAPAGGVGHLLIQLLMKK
HHHHHCCCCEEHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHH
IAKHNIKVTLICSAEKYKKLDSLIDTNQLTGWIDYTKNDSFPELQADVLLDLVGDEAGVR
HHHCCCEEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCH
ALDVVKESGRVYVLPTIWVDKLKGAGSQKNLSVEGYAAQRNGEDMARVLQLVADGQLTLR
HEEHHHHCCCEEEEEEEEEEHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEE
LQKTYPLSEVVIAHHELQKGDAFGKLVLKVS
EECCCCHHHHHHHHHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.065 {1,4-benzoquinone}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.26 {1,4-naphthoquinone}} 0.0024 {1,2-naphthoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA