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The map label for this gene is paaF [H]

Identifier: 93004841

GI number: 93004841

Start: 11501

End: 12304

Strand: Direct

Name: paaF [H]

Synonym: Pcryo_0010

Alternate gene names: 93004841

Gene position: 11501-12304 (Clockwise)

Preceding gene: 93004838

Following gene: 93004843

Centisome position: 0.38

GC content: 51.12

Gene sequence:

>804_bases
ATGACTACGGAAAGCCACAATAGCAATGACACTCGCATTACCTATGACATCCAAGATTACATCTGTCTGATCGGACTCAA
TCGCGTGGATAAACGCAATGCCTTTGATAGCCATATGATCAAGCAACTCTCTGACGCACTCACTCAATATGAAAATGATG
CGAATCTGCGTTGTGCGTTAATATTCGCGCATGGTGAGCATTTCACTGCTGGGCTTGATTTGATGGAGCTACAAGATAAA
TGGGATAAAGGCGCGTTTGAGTTTGCTGCCGACGAAATCGATCCGTGGGGAATCGGTGGGCAATTACGCAGTAAACCAGT
CGTCGTCGCAGTACAAGGCACGTGCTTTACCGCTGGGATTGAGCTGATGCTCAATAGTGATGTCGTCATCGCAAGTGATA
ACTGCAACTTTGCGCAAATGGAAGTCCAGCGCGGCATCATGCCCTTTGGCGGCGCGACGGTACGCTTTGTCGCGGCTGCT
GGCTGGCAAAAAGCCATGCCGTATCTGCTCACGGGCAAAGCGTTTGATGCGCAAACGGCTGATAGACTGAACTTGGTCAG
TGAAGTGGTGGCAAATGGAGAAGAGTATGAACATGCGCTGACCATCGCCCAAGAGATTTGCAAAGCCGCACCACTTGGCG
TACAAGGGCTGCTGTCATCGGCGCAAGATGCCAGCCGCAATGGGGCAGCTGCCGCGCTTGCTAATATCCATAGCTATTTG
CCGCCGCTCTTTCATTCAGAAGATGCTAAAGAGGGTGCGATGGCGATGGTTGAGAGACGTGAGGCTGATTTTAGGGGGCG
TTAG

Upstream 100 bases:

>100_bases
GAACGTATGTCTATATTGAAAGGAAGGTTTATTAGCTGTAGTAATATCAATTTAGTGTAATTTGTACTCTATAAATGAAT
GCTTTAAAAAGGATAAGACC

Downstream 100 bases:

>100_bases
ATCTTTTCTGAAGTTCAATCTATCTAAAGTCCCACGCCAAACACCTAAACCTAAGACCGTAATCGCAAATAGCAAAAACC
TCGCAAGCGCGAGGTCTCAT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTTESHNSNDTRITYDIQDYICLIGLNRVDKRNAFDSHMIKQLSDALTQYENDANLRCALIFAHGEHFTAGLDLMELQDK
WDKGAFEFAADEIDPWGIGGQLRSKPVVVAVQGTCFTAGIELMLNSDVVIASDNCNFAQMEVQRGIMPFGGATVRFVAAA
GWQKAMPYLLTGKAFDAQTADRLNLVSEVVANGEEYEHALTIAQEICKAAPLGVQGLLSSAQDASRNGAAAALANIHSYL
PPLFHSEDAKEGAMAMVERREADFRGR

Sequences:

>Translated_267_residues
MTTESHNSNDTRITYDIQDYICLIGLNRVDKRNAFDSHMIKQLSDALTQYENDANLRCALIFAHGEHFTAGLDLMELQDK
WDKGAFEFAADEIDPWGIGGQLRSKPVVVAVQGTCFTAGIELMLNSDVVIASDNCNFAQMEVQRGIMPFGGATVRFVAAA
GWQKAMPYLLTGKAFDAQTADRLNLVSEVVANGEEYEHALTIAQEICKAAPLGVQGLLSSAQDASRNGAAAALANIHSYL
PPLFHSEDAKEGAMAMVERREADFRGR
>Mature_266_residues
TTESHNSNDTRITYDIQDYICLIGLNRVDKRNAFDSHMIKQLSDALTQYENDANLRCALIFAHGEHFTAGLDLMELQDKW
DKGAFEFAADEIDPWGIGGQLRSKPVVVAVQGTCFTAGIELMLNSDVVIASDNCNFAQMEVQRGIMPFGGATVRFVAAAG
WQKAMPYLLTGKAFDAQTADRLNLVSEVVANGEEYEHALTIAQEICKAAPLGVQGLLSSAQDASRNGAAAALANIHSYLP
PLFHSEDAKEGAMAMVERREADFRGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=253, Percent_Identity=29.6442687747036, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI70995211, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4502327, Length=281, Percent_Identity=22.7758007117438, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI31542718, Length=188, Percent_Identity=28.1914893617021, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=31.8897637795276, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI221142681, Length=258, Percent_Identity=32.1705426356589, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787660, Length=272, Percent_Identity=25.7352941176471, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082183, Length=260, Percent_Identity=23.8461538461538, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=251, Percent_Identity=28.6852589641434, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=240, Percent_Identity=29.5833333333333, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560910, Length=196, Percent_Identity=28.0612244897959, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=267, Percent_Identity=23.9700374531835, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=196, Percent_Identity=25, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540306, Length=247, Percent_Identity=27.5303643724696, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650670, Length=226, Percent_Identity=31.858407079646, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129971, Length=266, Percent_Identity=27.8195488721804, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24653477, Length=266, Percent_Identity=27.8195488721804, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21357171, Length=211, Percent_Identity=29.3838862559242, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=28.2352941176471, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=26.046511627907, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29163; Mature: 29032

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTESHNSNDTRITYDIQDYICLIGLNRVDKRNAFDSHMIKQLSDALTQYENDANLRCAL
CCCCCCCCCCCEEEEEHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
IFAHGEHFTAGLDLMELQDKWDKGAFEFAADEIDPWGIGGQLRSKPVVVAVQGTCFTAGI
EEECCCEEECCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEECE
ELMLNSDVVIASDNCNFAQMEVQRGIMPFGGATVRFVAAAGWQKAMPYLLTGKAFDAQTA
EEEECCCEEEEECCCCHHHHHHHCCCCCCCCHHEEEEEHHCHHHCCCEEEECCCCCCCHH
DRLNLVSEVVANGEEYEHALTIAQEICKAAPLGVQGLLSSAQDASRNGAAAALANIHSYL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHC
PPLFHSEDAKEGAMAMVERREADFRGR
CCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTESHNSNDTRITYDIQDYICLIGLNRVDKRNAFDSHMIKQLSDALTQYENDANLRCAL
CCCCCCCCCCEEEEEHHHEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
IFAHGEHFTAGLDLMELQDKWDKGAFEFAADEIDPWGIGGQLRSKPVVVAVQGTCFTAGI
EEECCCEEECCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEECE
ELMLNSDVVIASDNCNFAQMEVQRGIMPFGGATVRFVAAAGWQKAMPYLLTGKAFDAQTA
EEEECCCEEEEECCCCHHHHHHHCCCCCCCCHHEEEEEHHCHHHCCCEEEECCCCCCCHH
DRLNLVSEVVANGEEYEHALTIAQEICKAAPLGVQGLLSSAQDASRNGAAAALANIHSYL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHC
PPLFHSEDAKEGAMAMVERREADFRGR
CCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]