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The map label for this gene is pdxH

Identifier: 92114023

GI number: 92114023

Start: 2158512

End: 2159159

Strand: Direct

Name: pdxH

Synonym: Csal_1900

Alternate gene names: 92114023

Gene position: 2158512-2159159 (Clockwise)

Preceding gene: 92114022

Following gene: 92114028

Centisome position: 58.39

GC content: 63.27

Gene sequence:

>648_bases
ATGAACTACGACATCGCCGACCTGCGACGCGATTACGCCGGCGAAACGCTCTCCGTCGAGAGTGCGCCGGCTTCGCCCCT
CGACCTGTTCCAGACGTGGTTTGCCGCCGCACGTGAGCACGAGACGCAGGACGCCAACGCCATGACGCTGGCCACCGTGG
ACAGTCAGGGACTCCCCCACGCGCGCGTGGTCCTGCTCAAGCAGCTCGACGACAAGGGGCTGGTATTCTTCACCAACTAC
CAGAGCCACAAAGGCAGCGAGCTGACCAACGTTCCCTATGCCGCTCTGGTCTTCTGGTGGCCCACGCTGCAGCGCCAGAT
ACGCATCGAGGGCCGCGTGGAAAAGGCCAGTGCCGAGGTCTCCGATGCCTACTTCGCCAACCGGCCCCGTGACAGCCAGC
TAGGTGCCTGGATTTCCCAGCAAAGCGTGGAAATTCCCGACCGCGACTGGCTGGAGGAGCGCAAGCAGCGCTTCGAGCAG
GTCTACGGCGAACAAACGGTGGAGCGTCCGCCTCACTGGGGAGGTTATCGGGTCCTGCCGTTTTTGCTGGAATTCTGGCA
GGGGCAACCCAATCGGCTACATGATCGCATCCGCTATCGTTACCATGAGCAGGATGCCGCCTGGAGCAAGACCCGCCTGG
CGCCCTGA

Upstream 100 bases:

>100_bases
CCTCGGTGACTGGTGCCTGCGCGCATGACGGAAACGCCCCCCGGCACCGGCTTGGGGCGCAGCACGCCAACACGACATGA
TCCTCTAGGAGAGAACGACC

Downstream 100 bases:

>100_bases
AACGCCACGTCTCATGGCATGTGGCCTCGCCAGCATCGAAAACGCCCGGTCCAATGGACCGGGCGTTTTCGATACGAGCA
TCTGGCGCCAGAAGGCGCCA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MNYDIADLRRDYAGETLSVESAPASPLDLFQTWFAAAREHETQDANAMTLATVDSQGLPHARVVLLKQLDDKGLVFFTNY
QSHKGSELTNVPYAALVFWWPTLQRQIRIEGRVEKASAEVSDAYFANRPRDSQLGAWISQQSVEIPDRDWLEERKQRFEQ
VYGEQTVERPPHWGGYRVLPFLLEFWQGQPNRLHDRIRYRYHEQDAAWSKTRLAP

Sequences:

>Translated_215_residues
MNYDIADLRRDYAGETLSVESAPASPLDLFQTWFAAAREHETQDANAMTLATVDSQGLPHARVVLLKQLDDKGLVFFTNY
QSHKGSELTNVPYAALVFWWPTLQRQIRIEGRVEKASAEVSDAYFANRPRDSQLGAWISQQSVEIPDRDWLEERKQRFEQ
VYGEQTVERPPHWGGYRVLPFLLEFWQGQPNRLHDRIRYRYHEQDAAWSKTRLAP
>Mature_215_residues
MNYDIADLRRDYAGETLSVESAPASPLDLFQTWFAAAREHETQDANAMTLATVDSQGLPHARVVLLKQLDDKGLVFFTNY
QSHKGSELTNVPYAALVFWWPTLQRQIRIEGRVEKASAEVSDAYFANRPRDSQLGAWISQQSVEIPDRDWLEERKQRFEQ
VYGEQTVERPPHWGGYRVLPFLLEFWQGQPNRLHDRIRYRYHEQDAAWSKTRLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=229, Percent_Identity=42.3580786026201, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1787926, Length=211, Percent_Identity=44.5497630331754, Blast_Score=181, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17553712, Length=223, Percent_Identity=39.9103139013453, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6319509, Length=208, Percent_Identity=38.9423076923077, Blast_Score=155, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24644901, Length=205, Percent_Identity=41.9512195121951, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI45551845, Length=205, Percent_Identity=41.9512195121951, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24644903, Length=166, Percent_Identity=31.9277108433735, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_CHRSD (Q1QWA6)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573951.1
- ProteinModelPortal:   Q1QWA6
- SMR:   Q1QWA6
- STRING:   Q1QWA6
- GeneID:   4026813
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1900
- NMPDR:   fig|290398.4.peg.2243
- eggNOG:   COG0259
- HOGENOM:   HBG327559
- OMA:   FTFFTNY
- BioCyc:   CSAL290398:CSAL_1900-MONOMER
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190
- TIGRFAMs:   TIGR00558

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 25050; Mature: 25050

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 62-62 BINDING 65-65 BINDING 67-67 BINDING 84-84 BINDING 124-124 BINDING 128-128 BINDING 132-132

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYDIADLRRDYAGETLSVESAPASPLDLFQTWFAAAREHETQDANAMTLATVDSQGLPH
CCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCH
ARVVLLKQLDDKGLVFFTNYQSHKGSELTNVPYAALVFWWPTLQRQIRIEGRVEKASAEV
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCHHHHHHHH
SDAYFANRPRDSQLGAWISQQSVEIPDRDWLEERKQRFEQVYGEQTVERPPHWGGYRVLP
HHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FLLEFWQGQPNRLHDRIRYRYHEQDAAWSKTRLAP
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNYDIADLRRDYAGETLSVESAPASPLDLFQTWFAAAREHETQDANAMTLATVDSQGLPH
CCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCH
ARVVLLKQLDDKGLVFFTNYQSHKGSELTNVPYAALVFWWPTLQRQIRIEGRVEKASAEV
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCHHHHHHHH
SDAYFANRPRDSQLGAWISQQSVEIPDRDWLEERKQRFEQVYGEQTVERPPHWGGYRVLP
HHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
FLLEFWQGQPNRLHDRIRYRYHEQDAAWSKTRLAP
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA