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The map label for this gene is pheS

Identifier: 92113926

GI number: 92113926

Start: 2049449

End: 2050468

Strand: Direct

Name: pheS

Synonym: Csal_1803

Alternate gene names: 92113926

Gene position: 2049449-2050468 (Clockwise)

Preceding gene: 92113925

Following gene: 92113927

Centisome position: 55.44

GC content: 62.25

Gene sequence:

>1020_bases
ATGGACCATCTCCCACAACTGGTCGCCGAGGCTCGCGCCGCCATCGAGAGCGCGGAGGATGTCCAGTCACTCGACGAGGT
TCGGGTGCGCTATCTGGGCAAGAAAGGTGAGATTACCGCTCTTCTCAAGGGGCTCGGCAAACTGCCGGCGGAAGAGCGTC
CCAAGGCCGGCGAGCAGATCAATGATGCCAAGCAAGTGCTGTCGGACGAGCTCGAGGCACGCAAGAAGCATCTGCAGGAC
GCCGAATTGAATGCACGCCTGGCCCAGGAGCGTATCGACGTGACGCTGCCCGGGCGCGGTGAGCCCACGGGGGGCTTGCA
TCCCGTGACCCGCACGCTCGAGCGTATCGAGTCCCTGTTCGCGCATATCGGCTTCGACGTGGCCGTGGGGCCCGAGCTCG
AAGACGACTATCACAACTTCGAGGCGCTCAATATTCCGGCCCACCATCCCGCACGGGGCATGGCGGATACGTTCTATTTC
GATGCGTCACGATTGCTGCGCACGCATACCTCGCCGGTGCAGGTGCGGACCATGAAGGAGCAGGCGCCGCCGATACGCAT
CGTCTGCCCGGGGCGGGTCTATCGCAGCGACTCGGATCTCACGCACACGCCGATGTTCCACCAGGTGGAAGGCCTGCTGG
TCGACGAGGACGTGAGCTTTGCCGACTTGAAGGGCACGATCGAGGATTTTCTCAAGGCGTTCTTCGAGCGGGAGTCGCTT
TCCGTGCGCTTCCGTCCTTCCTATTTCCCGTTTACCGAGCCCTCCGCCGAGGTCGATATCCAGTGCGTCATGTGCGGAGG
CGATGGCTGTCGTGTGTGTTCGCACAGCGGCTGGTTGGAAGTCATGGGGTGCGGAATGGTACACCCCGAGGTCTTTCGTC
ATTCGGGCATCGATGCCGAGCGTTACACCGGGTTCGCGTTCGGCATGGGCGCGGAGCGGTTGACGATGCTGCGCTACGGC
GTCAATGACCTGCGGCTGTTTTTCGAAAACGACTTGCGCTTCTTGCGCCAATTCGGCTGA

Upstream 100 bases:

>100_bases
CCGCAGGGGGAGAGCAGCCGCTCTTCCCCTGTTTTTTTGTCTGGACCATTGCCCGACGAGCGGTGGTTCACCACGGGCAC
TTAGCATCGGAGCTAGACGG

Downstream 100 bases:

>100_bases
TCAGCGACCACGGACACAGGAAGTAACATGAAATTTTCTGAAACATGGCTGCGCCATTGGGTCTCCCCCGACTGGACCAC
GCAGGCGCTGGCCGATCACA

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MDHLPQLVAEARAAIESAEDVQSLDEVRVRYLGKKGEITALLKGLGKLPAEERPKAGEQINDAKQVLSDELEARKKHLQD
AELNARLAQERIDVTLPGRGEPTGGLHPVTRTLERIESLFAHIGFDVAVGPELEDDYHNFEALNIPAHHPARGMADTFYF
DASRLLRTHTSPVQVRTMKEQAPPIRIVCPGRVYRSDSDLTHTPMFHQVEGLLVDEDVSFADLKGTIEDFLKAFFERESL
SVRFRPSYFPFTEPSAEVDIQCVMCGGDGCRVCSHSGWLEVMGCGMVHPEVFRHSGIDAERYTGFAFGMGAERLTMLRYG
VNDLRLFFENDLRFLRQFG

Sequences:

>Translated_339_residues
MDHLPQLVAEARAAIESAEDVQSLDEVRVRYLGKKGEITALLKGLGKLPAEERPKAGEQINDAKQVLSDELEARKKHLQD
AELNARLAQERIDVTLPGRGEPTGGLHPVTRTLERIESLFAHIGFDVAVGPELEDDYHNFEALNIPAHHPARGMADTFYF
DASRLLRTHTSPVQVRTMKEQAPPIRIVCPGRVYRSDSDLTHTPMFHQVEGLLVDEDVSFADLKGTIEDFLKAFFERESL
SVRFRPSYFPFTEPSAEVDIQCVMCGGDGCRVCSHSGWLEVMGCGMVHPEVFRHSGIDAERYTGFAFGMGAERLTMLRYG
VNDLRLFFENDLRFLRQFG
>Mature_339_residues
MDHLPQLVAEARAAIESAEDVQSLDEVRVRYLGKKGEITALLKGLGKLPAEERPKAGEQINDAKQVLSDELEARKKHLQD
AELNARLAQERIDVTLPGRGEPTGGLHPVTRTLERIESLFAHIGFDVAVGPELEDDYHNFEALNIPAHHPARGMADTFYF
DASRLLRTHTSPVQVRTMKEQAPPIRIVCPGRVYRSDSDLTHTPMFHQVEGLLVDEDVSFADLKGTIEDFLKAFFERESL
SVRFRPSYFPFTEPSAEVDIQCVMCGGDGCRVCSHSGWLEVMGCGMVHPEVFRHSGIDAERYTGFAFGMGAERLTMLRYG
VNDLRLFFENDLRFLRQFG

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5729820, Length=238, Percent_Identity=33.6134453781513, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4758340, Length=272, Percent_Identity=28.6764705882353, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1788007, Length=338, Percent_Identity=65.9763313609467, Blast_Score=456, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17508957, Length=274, Percent_Identity=28.4671532846715, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32563657, Length=274, Percent_Identity=28.4671532846715, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32566635, Length=250, Percent_Identity=31.6, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321087, Length=273, Percent_Identity=29.3040293040293, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325304, Length=280, Percent_Identity=27.1428571428571, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18858079, Length=275, Percent_Identity=28.3636363636364, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17137424, Length=249, Percent_Identity=31.7269076305221, Blast_Score=107, Evalue=8e-24,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_CHRSD (Q1QWK3)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573854.1
- ProteinModelPortal:   Q1QWK3
- SMR:   Q1QWK3
- STRING:   Q1QWK3
- GeneID:   4027360
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1803
- NMPDR:   fig|290398.4.peg.3163
- eggNOG:   COG0016
- HOGENOM:   HBG284353
- OMA:   FRASYFP
- BioCyc:   CSAL290398:CSAL_1803-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38102; Mature: 38102

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLPQLVAEARAAIESAEDVQSLDEVRVRYLGKKGEITALLKGLGKLPAEERPKAGEQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHH
NDAKQVLSDELEARKKHLQDAELNARLAQERIDVTLPGRGEPTGGLHPVTRTLERIESLF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHH
AHIGFDVAVGPELEDDYHNFEALNIPAHHPARGMADTFYFDASRLLRTHTSPVQVRTMKE
HHCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHH
QAPPIRIVCPGRVYRSDSDLTHTPMFHQVEGLLVDEDVSFADLKGTIEDFLKAFFERESL
CCCCEEEEECCCEECCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
SVRFRPSYFPFTEPSAEVDIQCVMCGGDGCRVCSHSGWLEVMGCGMVHPEVFRHSGIDAE
EEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCHH
RYTGFAFGMGAERLTMLRYGVNDLRLFFENDLRFLRQFG
HHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDHLPQLVAEARAAIESAEDVQSLDEVRVRYLGKKGEITALLKGLGKLPAEERPKAGEQI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHH
NDAKQVLSDELEARKKHLQDAELNARLAQERIDVTLPGRGEPTGGLHPVTRTLERIESLF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHH
AHIGFDVAVGPELEDDYHNFEALNIPAHHPARGMADTFYFDASRLLRTHTSPVQVRTMKE
HHCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHH
QAPPIRIVCPGRVYRSDSDLTHTPMFHQVEGLLVDEDVSFADLKGTIEDFLKAFFERESL
CCCCEEEEECCCEECCCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCC
SVRFRPSYFPFTEPSAEVDIQCVMCGGDGCRVCSHSGWLEVMGCGMVHPEVFRHSGIDAE
EEEECCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHCCCCHH
RYTGFAFGMGAERLTMLRYGVNDLRLFFENDLRFLRQFG
HHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA