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The map label for this gene is exuT [H]

Identifier: 92112272

GI number: 92112272

Start: 158478

End: 159761

Strand: Direct

Name: exuT [H]

Synonym: Csal_0137

Alternate gene names: 92112272

Gene position: 158478-159761 (Clockwise)

Preceding gene: 92112271

Following gene: 92112273

Centisome position: 4.29

GC content: 58.1

Gene sequence:

>1284_bases
ATGACGACAACGACTGCATCTTCCCAATCATCGGCACCGGCAGCCGAGACACCTGACGACGTACAACACGCAGGCATCAA
ACGCTGGGCGATTCCTTTTGCCTTGCTTTGCTGCGTCATTCTTTCCTTTTTCGACAAGATCAGCATCGCGGTACTGCTTT
CCAGCCCTGCCTTCCAAGGCGCATTGGGTGTAGAAGGCGAAACCACCAAGCTGGGATTCTTGATGACGGGGTTTCTCCTG
TCCTACGGCTTCTCTTCGATGTTCCTTGGGTTCTTGAGCGACATCATCAGCCCCAAGAAATGTCTCTACGCCATGCTGGT
GTTGACGGCCGTCATCATGACGATCATGGGGTTCGCGGAATCCTACGCTCAGATGTTGACGTTGCGCATCGTGCTGGGCA
TTGCCGAGGGGCCGATGTTCGCCATCGCCTATACCATCGTCAAGCGTACCTTCGCACCCCGCGAACAGGCGCGTGCCACC
ATGCTCTGGCTTTTAGGCACACCCATCGGTGCGTCGATCGGATTCCCCTTCACGATCTATATTCTGGATAACTTTGGATG
GCGGGCGACCTTCTTCGCCATGGCCTTGCTGACGATTCCTCTTCTCATGCTGGTGGTATGGGTGTTTCGCAAGGTCGATG
TATCGACGAAATCGCCCTTGCAAAAGGCGCGCGGCGACAAGCATGTGCCCCTGTCCAGCCATCGCCAGTCGACTCGGGAA
TTGTTCGGAAATCTCTCCTTCTGGGCGATCTGTGTCTTCAATATCGCGTTCCTGGCCTATCTCTGGGGACTCAATAGCTG
GCTGCCGACCTACCTGGTCGAGGACAAGGGCATCGACCTCGATTCGGCGGGCATTTTTTCCTCCCTTCCGTTCATCGCGA
TGCTGGTCGGCGAGGTCGTGGGAGCGTTCGTCTCCGATCGGTTCGACAAGCGGGCGTTGATGTGTGCGTTCTCGTTGTTC
GGCGCCGGTCTCGGCCTGCTGCTCGTGCTGTCCATCGACGCCTCGAATATCGCCATGATCTCCGCCATGTCGTTCAGCGC
CATGTGCTGGGGCGTGGGCGCCCCCAACATCTTCGCCCTGCTGGCCAAGGCGACACCTGCCAAGGTCAGTGCCACGGCCG
GCGGCATTCTCAATGGATTCGGCAATTTTTCCGGTGCTTTGACGCCGGTCATCATCGGCGCCCTGATTGCCTCGACCGGC
AATATGACGGCCGGACTCTTGTTCATGGCGGTGTTGGCCTTTGCCGGCGGTGCTGTGCTGTTGCCCCTGGTGCGGCGTTA
CTGA

Upstream 100 bases:

>100_bases
CGATCCCGACATGCTGGGTGATCCCACCAGCAACCTCATGCGGCTTCGGTAGCGAATAACCGACGTCAAACCTCCATAAC
AATGACAATGGTAATGTCCC

Downstream 100 bases:

>100_bases
ACCGCCAGGATCGCGCCGTCTCTGCGCGGCGCTTACCCCTGAGCCTATAAAGAGGAACCATCCAATGACTCAATCTATTG
CGACCTGGAAGCGCCCGGAA

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MTTTTASSQSSAPAAETPDDVQHAGIKRWAIPFALLCCVILSFFDKISIAVLLSSPAFQGALGVEGETTKLGFLMTGFLL
SYGFSSMFLGFLSDIISPKKCLYAMLVLTAVIMTIMGFAESYAQMLTLRIVLGIAEGPMFAIAYTIVKRTFAPREQARAT
MLWLLGTPIGASIGFPFTIYILDNFGWRATFFAMALLTIPLLMLVVWVFRKVDVSTKSPLQKARGDKHVPLSSHRQSTRE
LFGNLSFWAICVFNIAFLAYLWGLNSWLPTYLVEDKGIDLDSAGIFSSLPFIAMLVGEVVGAFVSDRFDKRALMCAFSLF
GAGLGLLLVLSIDASNIAMISAMSFSAMCWGVGAPNIFALLAKATPAKVSATAGGILNGFGNFSGALTPVIIGALIASTG
NMTAGLLFMAVLAFAGGAVLLPLVRRY

Sequences:

>Translated_427_residues
MTTTTASSQSSAPAAETPDDVQHAGIKRWAIPFALLCCVILSFFDKISIAVLLSSPAFQGALGVEGETTKLGFLMTGFLL
SYGFSSMFLGFLSDIISPKKCLYAMLVLTAVIMTIMGFAESYAQMLTLRIVLGIAEGPMFAIAYTIVKRTFAPREQARAT
MLWLLGTPIGASIGFPFTIYILDNFGWRATFFAMALLTIPLLMLVVWVFRKVDVSTKSPLQKARGDKHVPLSSHRQSTRE
LFGNLSFWAICVFNIAFLAYLWGLNSWLPTYLVEDKGIDLDSAGIFSSLPFIAMLVGEVVGAFVSDRFDKRALMCAFSLF
GAGLGLLLVLSIDASNIAMISAMSFSAMCWGVGAPNIFALLAKATPAKVSATAGGILNGFGNFSGALTPVIIGALIASTG
NMTAGLLFMAVLAFAGGAVLLPLVRRY
>Mature_426_residues
TTTTASSQSSAPAAETPDDVQHAGIKRWAIPFALLCCVILSFFDKISIAVLLSSPAFQGALGVEGETTKLGFLMTGFLLS
YGFSSMFLGFLSDIISPKKCLYAMLVLTAVIMTIMGFAESYAQMLTLRIVLGIAEGPMFAIAYTIVKRTFAPREQARATM
LWLLGTPIGASIGFPFTIYILDNFGWRATFFAMALLTIPLLMLVVWVFRKVDVSTKSPLQKARGDKHVPLSSHRQSTREL
FGNLSFWAICVFNIAFLAYLWGLNSWLPTYLVEDKGIDLDSAGIFSSLPFIAMLVGEVVGAFVSDRFDKRALMCAFSLFG
AGLGLLLVLSIDASNIAMISAMSFSAMCWGVGAPNIFALLAKATPAKVSATAGGILNGFGNFSGALTPVIIGALIASTGN
MTAGLLFMAVLAFAGGAVLLPLVRRY

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=381, Percent_Identity=21.5223097112861, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI9966811, Length=377, Percent_Identity=19.893899204244, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21322234, Length=350, Percent_Identity=22, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789152, Length=427, Percent_Identity=22.4824355971897, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367379, Length=439, Percent_Identity=22.0956719817768, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082320, Length=419, Percent_Identity=22.1957040572792, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=21.3457076566125, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788573, Length=320, Percent_Identity=23.125, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082071, Length=405, Percent_Identity=22.2222222222222, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115533556, Length=426, Percent_Identity=23.2394366197183, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533554, Length=353, Percent_Identity=24.0793201133144, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24584153, Length=384, Percent_Identity=22.3958333333333, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20130167, Length=320, Percent_Identity=22.1875, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45710; Mature: 45579

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTASSQSSAPAAETPDDVQHAGIKRWAIPFALLCCVILSFFDKISIAVLLSSPAFQG
CCCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
ALGVEGETTKLGFLMTGFLLSYGFSSMFLGFLSDIISPKKCLYAMLVLTAVIMTIMGFAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SYAQMLTLRIVLGIAEGPMFAIAYTIVKRTFAPREQARATMLWLLGTPIGASIGFPFTIY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCEEEE
ILDNFGWRATFFAMALLTIPLLMLVVWVFRKVDVSTKSPLQKARGDKHVPLSSHRQSTRE
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHH
LFGNLSFWAICVFNIAFLAYLWGLNSWLPTYLVEDKGIDLDSAGIFSSLPFIAMLVGEVV
HHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHH
GAFVSDRFDKRALMCAFSLFGAGLGLLLVLSIDASNIAMISAMSFSAMCWGVGAPNIFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LAKATPAKVSATAGGILNGFGNFSGALTPVIIGALIASTGNMTAGLLFMAVLAFAGGAVL
HHHCCCCCHHHHHCHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHH
LPLVRRY
HHHHHCC
>Mature Secondary Structure 
TTTTASSQSSAPAAETPDDVQHAGIKRWAIPFALLCCVILSFFDKISIAVLLSSPAFQG
CCCCCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
ALGVEGETTKLGFLMTGFLLSYGFSSMFLGFLSDIISPKKCLYAMLVLTAVIMTIMGFAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
SYAQMLTLRIVLGIAEGPMFAIAYTIVKRTFAPREQARATMLWLLGTPIGASIGFPFTIY
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCEEEE
ILDNFGWRATFFAMALLTIPLLMLVVWVFRKVDVSTKSPLQKARGDKHVPLSSHRQSTRE
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHH
LFGNLSFWAICVFNIAFLAYLWGLNSWLPTYLVEDKGIDLDSAGIFSSLPFIAMLVGEVV
HHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHH
GAFVSDRFDKRALMCAFSLFGAGLGLLLVLSIDASNIAMISAMSFSAMCWGVGAPNIFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LAKATPAKVSATAGGILNGFGNFSGALTPVIIGALIASTGNMTAGLLFMAVLAFAGGAVL
HHHCCCCCHHHHHCHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHH
LPLVRRY
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]