Click here to switch to the map view.

The map label for this gene is tlpA [H]

Identifier: 92109747

GI number: 92109747

Start: 92795

End: 93376

Strand: Reverse

Name: tlpA [H]

Synonym: Nham_4643

Alternate gene names: 92109747

Gene position: 93376-92795 (Counterclockwise)

Preceding gene: 92109748

Following gene: 92109746

Centisome position: 76.91

GC content: 60.48

Gene sequence:

>582_bases
TTGCGCATCGCAACAGCGGTCCTCGTTTCAGTGGCGGCAACGCTCTCGAGCGCGACTGCGCACCCCGAATCGCTCGATCC
GCCGACGCTGCGCAACGGGATAAGCCAGTTCGTTCTGGAGGAGCCGCTTAGGCCTGCGCCGCTCATGCGACTCCGCGGCC
TCGACGGCCGCACCCTGAGTATGGACAAGTTCTACGGAAAGGTCGTTCTCCTCAATTTCTGGGCCAGTTGGTGTGCTCCT
TGTGTGGAGGAAATGCCGTCTCTCGAGGCGCTTGCAGCGAGTCTTCCGTCTGACCGCTTCGTCGTTGTCGCGGTCTCACT
CGACAGCGGCGATGGTCGGCAGGTGAAGTCGTTCGTCAAGCGACACAATCTTCGGCATCTGACCGTCGTGCGCGATCCCA
ACCACGAGTTCGGTGCGTTGACCAGTGAGGGGAAGCCGGAACCAACCATGCCCGTCTATGGCTATCCAACCACCTACATC
CTGGACAAGCGGGGCTTGGTCACGGGGTTTCTGGTGGGTCCCACGACGTGGGATTCTCCTCTCGCGCGGTCGTTCATCGA
CTATTTCATCAATCTCAAGTGA

Upstream 100 bases:

>100_bases
GGTTGATCGTTGCGCTTGGTCGGATCTTCGGGCACCGGATGTTGTCCTGGGTGGCACCCAAGCCGCTGGGCCGTGCCCCA
TGATGTGGGTCCATCCGTTC

Downstream 100 bases:

>100_bases
CGGCTTCGCCGTTGGCTCACGAAACAGAGCGGAGCACGGATGACGATTTTAGGTATACTCGGCGGAAGCGGCGTTTACGA
CATCGCCGAGCTGGAAGATC

Product: putative thiol--disulfide interchange redox-active center transmembrane protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MRIATAVLVSVAATLSSATAHPESLDPPTLRNGISQFVLEEPLRPAPLMRLRGLDGRTLSMDKFYGKVVLLNFWASWCAP
CVEEMPSLEALAASLPSDRFVVVAVSLDSGDGRQVKSFVKRHNLRHLTVVRDPNHEFGALTSEGKPEPTMPVYGYPTTYI
LDKRGLVTGFLVGPTTWDSPLARSFIDYFINLK

Sequences:

>Translated_193_residues
MRIATAVLVSVAATLSSATAHPESLDPPTLRNGISQFVLEEPLRPAPLMRLRGLDGRTLSMDKFYGKVVLLNFWASWCAP
CVEEMPSLEALAASLPSDRFVVVAVSLDSGDGRQVKSFVKRHNLRHLTVVRDPNHEFGALTSEGKPEPTMPVYGYPTTYI
LDKRGLVTGFLVGPTTWDSPLARSFIDYFINLK
>Mature_193_residues
MRIATAVLVSVAATLSSATAHPESLDPPTLRNGISQFVLEEPLRPAPLMRLRGLDGRTLSMDKFYGKVVLLNFWASWCAP
CVEEMPSLEALAASLPSDRFVVVAVSLDSGDGRQVKSFVKRHNLRHLTVVRDPNHEFGALTSEGKPEPTMPVYGYPTTYI
LDKRGLVTGFLVGPTTWDSPLARSFIDYFINLK

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21274; Mature: 21274

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIATAVLVSVAATLSSATAHPESLDPPTLRNGISQFVLEEPLRPAPLMRLRGLDGRTLS
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEE
MDKFYGKVVLLNFWASWCAPCVEEMPSLEALAASLPSDRFVVVAVSLDSGDGRQVKSFVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHH
RHNLRHLTVVRDPNHEFGALTSEGKPEPTMPVYGYPTTYILDKRGLVTGFLVGPTTWDSP
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHH
LARSFIDYFINLK
HHHHHHHHHHCCC
>Mature Secondary Structure
MRIATAVLVSVAATLSSATAHPESLDPPTLRNGISQFVLEEPLRPAPLMRLRGLDGRTLS
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEE
MDKFYGKVVLLNFWASWCAPCVEEMPSLEALAASLPSDRFVVVAVSLDSGDGRQVKSFVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHH
RHNLRHLTVVRDPNHEFGALTSEGKPEPTMPVYGYPTTYILDKRGLVTGFLVGPTTWDSP
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCHH
LARSFIDYFINLK
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]