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The map label for this gene is pntB [H]

Identifier: 91790375

GI number: 91790375

Start: 4806053

End: 4807477

Strand: Reverse

Name: pntB [H]

Synonym: Bpro_4544

Alternate gene names: 91790375

Gene position: 4807477-4806053 (Counterclockwise)

Preceding gene: 91790376

Following gene: 91790374

Centisome position: 92.45

GC content: 63.58

Gene sequence:

>1425_bases
ATGAGCATGAACCTCGTCACGCTGCTGTACCTGGTGGCCTCTGTTTGCTTCATTCAGGCGCTCAAGGGCCTGTCGCACCC
CACCAGCTCCATCCGCGGCAACCTGTTCGGCATGGTCGGCATGGCCATTGCCATGCTGACCACGGCCGCGCTGATCGTCG
AAATCTCGGGCGGCAAGGCCCTCGGCATGGCTTATGTACTGGTGGGCCTGGTGGTCGGCGGGGGCTATGGCGCCTGGCGC
GCCAAGACGGTCGAAATGACCAAGATGCCCGAGCTGGTCGCCTTCTTCCACAGCATGATTGGCTTGGCCGCGGTCTTCAT
CGCCGTGGCCGCCGTCGCCGAGCCCTACGCCTTTGGCATCGCGGCCAAAGGCAGCCCCATCCCCACCGGCAACCGGCTGG
AGCTGTTCCTCGGCGCGGCCATTGGCGCCATCACCTTCAGCGGCTCGGTGATCGCCTTCGGCAAACTCTCGGGCACTTAC
AAGTTCCGCCTGTTCCAGGGCGCGCCGGTGCAGTTTGCCGGCCAGCACAAGCTCAACCTGATCCTGGGCCTGCTGACCAT
CGGCCTGGGGCTGGTGTTCATGTTCACGGGCAGCTGGCCAGCCTTTTTCGCGATGCTGGCGCTGAGCTTCGTGATGGGCG
TGCTCATCATCATCCCGATCGGTGGCGCCGACATGCCGGTGGTGGTGTCCATGCTCAACAGCTATTCGGGCTGGGCCGCG
GCCGGCATCGGTTTTTCCCTGAACAACTCGATGCTGATCATTGCTGGCTCGCTGGTCGGCTCGTCGGGTGCGATTCTCTC
GTACATCATGTGCAAGGCGATGAACCGCTCCTTCTTCAACGTGATCCTGGGCGGCTTCGGCGGCGAGGCGGGCACTGCCG
TGGCCGGCACGAAAGAGCAGCGCCCGGTCAAGTCCGGCTCGGCCGATGACGCCGCCTACATCCTGGGCAACGCCGAAACC
GTGATCATCGTTCCCGGCTACGGCCTGGCGGTGGCGCGCGCGCAGCATGCGGTGAACGAGCTGGCCGAAAAACTCATTCA
CCGCGGCGTCAACGTGAAGTACGCCATCCACCCGGTGGCCGGCCGCATGCCGGGCCACATGAACGTGCTGCTGGCCGAGG
CCGAGGTGCCCTACGACCAGGTGTTCGAGATGGAAGACATCAACGGTGAGTTTGGGCAGGCCGACGTGGCGATCATTCTG
GGTGCCAACGACGTGGTGAATCCGGCCGCGCTCACCAAGGGCAGCCCGATCTACGGCATGCCGATTCTCGAGGCGTACCG
GGCCAAGACCGTCATCGTCAACAAACGCTCCATGGCGGCCGGCTACGCGGGCCTGGACAACGAGTTGTTCTACATGGACA
AAACCATGATGGTGTTTGGCGATGCCAAAAAGGTGATTGAGGACATGGGCAAGGCGATCGAGTAA

Upstream 100 bases:

>100_bases
CCGTCAACATCTTCGGCGGCTTTCTGGTGACGCGCCGGATGCTGGAGATGTTCCGCAAGAAAGAAAAGAAAGTGGCCGCG
CCCGCTGAAGGAGCCGCCAA

Downstream 100 bases:

>100_bases
ACAGGCGAGTAAACGGAAACGGGCGAGTAAAAGCGGGCTGTGGCCGCACCGGGGGCCATCCATGCCGGCTCCCGGACAGC
GAGGGTTCCTCCTTCCCACC

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSMNLVTLLYLVASVCFIQALKGLSHPTSSIRGNLFGMVGMAIAMLTTAALIVEISGGKALGMAYVLVGLVVGGGYGAWR
AKTVEMTKMPELVAFFHSMIGLAAVFIAVAAVAEPYAFGIAAKGSPIPTGNRLELFLGAAIGAITFSGSVIAFGKLSGTY
KFRLFQGAPVQFAGQHKLNLILGLLTIGLGLVFMFTGSWPAFFAMLALSFVMGVLIIIPIGGADMPVVVSMLNSYSGWAA
AGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGGEAGTAVAGTKEQRPVKSGSADDAAYILGNAET
VIIVPGYGLAVARAQHAVNELAEKLIHRGVNVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMEDINGEFGQADVAIIL
GANDVVNPAALTKGSPIYGMPILEAYRAKTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMGKAIE

Sequences:

>Translated_474_residues
MSMNLVTLLYLVASVCFIQALKGLSHPTSSIRGNLFGMVGMAIAMLTTAALIVEISGGKALGMAYVLVGLVVGGGYGAWR
AKTVEMTKMPELVAFFHSMIGLAAVFIAVAAVAEPYAFGIAAKGSPIPTGNRLELFLGAAIGAITFSGSVIAFGKLSGTY
KFRLFQGAPVQFAGQHKLNLILGLLTIGLGLVFMFTGSWPAFFAMLALSFVMGVLIIIPIGGADMPVVVSMLNSYSGWAA
AGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGGEAGTAVAGTKEQRPVKSGSADDAAYILGNAET
VIIVPGYGLAVARAQHAVNELAEKLIHRGVNVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMEDINGEFGQADVAIIL
GANDVVNPAALTKGSPIYGMPILEAYRAKTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMGKAIE
>Mature_473_residues
SMNLVTLLYLVASVCFIQALKGLSHPTSSIRGNLFGMVGMAIAMLTTAALIVEISGGKALGMAYVLVGLVVGGGYGAWRA
KTVEMTKMPELVAFFHSMIGLAAVFIAVAAVAEPYAFGIAAKGSPIPTGNRLELFLGAAIGAITFSGSVIAFGKLSGTYK
FRLFQGAPVQFAGQHKLNLILGLLTIGLGLVFMFTGSWPAFFAMLALSFVMGVLIIIPIGGADMPVVVSMLNSYSGWAAA
GIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGGEAGTAVAGTKEQRPVKSGSADDAAYILGNAETV
IIVPGYGLAVARAQHAVNELAEKLIHRGVNVKYAIHPVAGRMPGHMNVLLAEAEVPYDQVFEMEDINGEFGQADVAIILG
ANDVVNPAALTKGSPIYGMPILEAYRAKTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMGKAIE

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=480, Percent_Identity=44.1666666666667, Blast_Score=354, Evalue=1e-97,
Organism=Homo sapiens, GI122939153, Length=480, Percent_Identity=44.1666666666667, Blast_Score=354, Evalue=1e-97,
Organism=Escherichia coli, GI1787886, Length=479, Percent_Identity=50.7306889352818, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17550456, Length=479, Percent_Identity=43.4237995824635, Blast_Score=335, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49595; Mature: 49464

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNLVTLLYLVASVCFIQALKGLSHPTSSIRGNLFGMVGMAIAMLTTAALIVEISGGKA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCH
LGMAYVLVGLVVGGGYGAWRAKTVEMTKMPELVAFFHSMIGLAAVFIAVAAVAEPYAFGI
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEE
AAKGSPIPTGNRLELFLGAAIGAITFSGSVIAFGKLSGTYKFRLFQGAPVQFAGQHKLNL
ECCCCCCCCCCCEEEEEHHHHHHEEECCCEEEEEECCCEEEEEEEECCCCEECCCHHHHH
ILGLLTIGLGLVFMFTGSWPAFFAMLALSFVMGVLIIIPIGGADMPVVVSMLNSYSGWAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCEE
AGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGGEAGTAVAGTKEQ
ECCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEECCCCCC
RPVKSGSADDAAYILGNAETVIIVPGYGLAVARAQHAVNELAEKLIHRGVNVKYAIHPVA
CCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GRMPGHMNVLLAEAEVPYDQVFEMEDINGEFGQADVAIILGANDVVNPAALTKGSPIYGM
CCCCCCCEEEEEECCCCHHHHEEHHCCCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCC
PILEAYRAKTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMGKAIE
HHHHHHCCEEEEEECCHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
SMNLVTLLYLVASVCFIQALKGLSHPTSSIRGNLFGMVGMAIAMLTTAALIVEISGGKA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCH
LGMAYVLVGLVVGGGYGAWRAKTVEMTKMPELVAFFHSMIGLAAVFIAVAAVAEPYAFGI
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEE
AAKGSPIPTGNRLELFLGAAIGAITFSGSVIAFGKLSGTYKFRLFQGAPVQFAGQHKLNL
ECCCCCCCCCCCEEEEEHHHHHHEEECCCEEEEEECCCEEEEEEEECCCCEECCCHHHHH
ILGLLTIGLGLVFMFTGSWPAFFAMLALSFVMGVLIIIPIGGADMPVVVSMLNSYSGWAA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCCEE
AGIGFSLNNSMLIIAGSLVGSSGAILSYIMCKAMNRSFFNVILGGFGGEAGTAVAGTKEQ
ECCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEECCCCCC
RPVKSGSADDAAYILGNAETVIIVPGYGLAVARAQHAVNELAEKLIHRGVNVKYAIHPVA
CCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GRMPGHMNVLLAEAEVPYDQVFEMEDINGEFGQADVAIILGANDVVNPAALTKGSPIYGM
CCCCCCCEEEEEECCCCHHHHEEHHCCCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCC
PILEAYRAKTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMGKAIE
HHHHHHCCEEEEEECCHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]