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The map label for this gene is mtnN [H]

Identifier: 91790373

GI number: 91790373

Start: 4803246

End: 4804055

Strand: Reverse

Name: mtnN [H]

Synonym: Bpro_4542

Alternate gene names: 91790373

Gene position: 4804055-4803246 (Counterclockwise)

Preceding gene: 91790374

Following gene: 91790372

Centisome position: 92.38

GC content: 64.2

Gene sequence:

>810_bases
ATGCCTGCGCGGTTTTACCCCGGCCTTTGTGTGCAAAATCTGCCCATGCCGCTCAACGCCCTCCCTCCCGCCGTACCGAT
TGCCATCCTCAGTGCACTGCTTGAGGAGCAGCACGGCCTCATGGAGTTGCTGCAGCAACCGCACAAGGTGACCCACGCGG
GACGTGACTTCTGGTTGGGCGACCTGCACGGCCGGCCGGTGGTACTGGCCCTGTCCAAAATTGGCAAGGTAGCCGCCGCT
ACCACCGCCACAGCCCTGATCGAACGCTTCGCGGTCAGCCGTATCGTGTTTACCGGCGTGGCGGGCGGCCTGGGTAACGG
CGTTAACGTGGGTGATGTCGTGGTCGCTACCGATTTTGTACAGCATGACCTGGATGCCTCGCCGCTCTTTCCGCGCTACG
AGGTGCCGCTGTACGGCAAGACCCGTTTCGAAGGCGACCCCGCCTTGACGGCCCTGCTGTTCGATGCCGCCCGCACGGCG
CTGGCAAGTGGCCACGCCAGCCAGGCATTTCCGGGTGCCCGCGTCCACCGGGGCCTGCTGGCCAGTGGTGACCGGTTTGT
CTCAGGCGCCCAGGAATCCGGCGCATTGCGCGCGGCGCTGGCCGCTGCCGGCCATGAGGTGCTGGCGGTGGAGATGGAGG
GGGCGGCCGTGGCACAGGTTTGCCATGACTATGGCGTGCCGTTTGCCGCAGTCCGCACGATTTCAGACCGTGCAGACGAC
AGCGCTCACGTCGATTTTCCGCGCTTTGTGAAGGAAGTGGCGCGCCATTACGCCCATGTGATTGTTGAGCGATTGTTGAT
TTCGCTGTAA

Upstream 100 bases:

>100_bases
AAATCCTTCGCCGCGAGCTGCGCGACAAAAAGTGAGCGGCGCGAACAAGTTTTAGAGCCTGCAAAGGTTTTCTACGGGGC
GGCGCAAGTCGCCCCTTTTT

Downstream 100 bases:

>100_bases
ACAAAATCGCCGGTTGCGACCGTCGTATTCCGTACTCGTACTGGTTGGGCTGAGAGCTTTTCTGAGATCTGGCGGGCGGG
TTGTCTCGCGGCCTGCTACC

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MPARFYPGLCVQNLPMPLNALPPAVPIAILSALLEEQHGLMELLQQPHKVTHAGRDFWLGDLHGRPVVLALSKIGKVAAA
TTATALIERFAVSRIVFTGVAGGLGNGVNVGDVVVATDFVQHDLDASPLFPRYEVPLYGKTRFEGDPALTALLFDAARTA
LASGHASQAFPGARVHRGLLASGDRFVSGAQESGALRAALAAAGHEVLAVEMEGAAVAQVCHDYGVPFAAVRTISDRADD
SAHVDFPRFVKEVARHYAHVIVERLLISL

Sequences:

>Translated_269_residues
MPARFYPGLCVQNLPMPLNALPPAVPIAILSALLEEQHGLMELLQQPHKVTHAGRDFWLGDLHGRPVVLALSKIGKVAAA
TTATALIERFAVSRIVFTGVAGGLGNGVNVGDVVVATDFVQHDLDASPLFPRYEVPLYGKTRFEGDPALTALLFDAARTA
LASGHASQAFPGARVHRGLLASGDRFVSGAQESGALRAALAAAGHEVLAVEMEGAAVAQVCHDYGVPFAAVRTISDRADD
SAHVDFPRFVKEVARHYAHVIVERLLISL
>Mature_268_residues
PARFYPGLCVQNLPMPLNALPPAVPIAILSALLEEQHGLMELLQQPHKVTHAGRDFWLGDLHGRPVVLALSKIGKVAAAT
TATALIERFAVSRIVFTGVAGGLGNGVNVGDVVVATDFVQHDLDASPLFPRYEVPLYGKTRFEGDPALTALLFDAARTAL
ASGHASQAFPGARVHRGLLASGDRFVSGAQESGALRAALAAAGHEVLAVEMEGAAVAQVCHDYGVPFAAVRTISDRADDS
AHVDFPRFVKEVARHYAHVIVERLLISL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=245, Percent_Identity=36.734693877551, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 28515; Mature: 28384

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARFYPGLCVQNLPMPLNALPPAVPIAILSALLEEQHGLMELLQQPHKVTHAGRDFWLG
CCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEE
DLHGRPVVLALSKIGKVAAATTATALIERFAVSRIVFTGVAGGLGNGVNVGDVVVATDFV
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
QHDLDASPLFPRYEVPLYGKTRFEGDPALTALLFDAARTALASGHASQAFPGARVHRGLL
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASGDRFVSGAQESGALRAALAAAGHEVLAVEMEGAAVAQVCHDYGVPFAAVRTISDRADD
HCCCHHHCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHCCCC
SAHVDFPRFVKEVARHYAHVIVERLLISL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PARFYPGLCVQNLPMPLNALPPAVPIAILSALLEEQHGLMELLQQPHKVTHAGRDFWLG
CCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEE
DLHGRPVVLALSKIGKVAAATTATALIERFAVSRIVFTGVAGGLGNGVNVGDVVVATDFV
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
QHDLDASPLFPRYEVPLYGKTRFEGDPALTALLFDAARTALASGHASQAFPGARVHRGLL
HHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ASGDRFVSGAQESGALRAALAAAGHEVLAVEMEGAAVAQVCHDYGVPFAAVRTISDRADD
HCCCHHHCCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHCCCC
SAHVDFPRFVKEVARHYAHVIVERLLISL
CCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA