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The map label for this gene is panE [C]

Identifier: 91790339

GI number: 91790339

Start: 4761633

End: 4762640

Strand: Reverse

Name: panE [C]

Synonym: Bpro_4507

Alternate gene names: 91790339

Gene position: 4762640-4761633 (Counterclockwise)

Preceding gene: 91790343

Following gene: 91790338

Centisome position: 91.58

GC content: 65.77

Gene sequence:

>1008_bases
ATGGACAACATGGATGGGTCTGTCCAGAATTCACGCCTGGATCAAGAAGGAGTCGCGGTGAAGATTTGTGTTCTGGGCGC
CGGCGCGCTGGGTTGCGCCATCGGCGGTGTGTTGACCGAGGCCGGCCATGAGGTGTGGCTGATCAACCGTAATGCGGAGC
AGGTCGACGCCATGAACAGCCGCGGGCTGATCCTGCGCGACGACGGTGCCGACCGCGCCGTGCAGGTGCATGCCGCCACC
ACCGCCCAGGGCGTGAACATGGACACGGGCGCCGTGGACCTGGTGATCGTGCTGGTCAAGTCCTTCCATACGCGCCAGGC
CATGGAAGCGGCGACCTCTTTGCTCGGGCCGGACACCGCCGTGCTGTCGCTGCAAAACGGCCTCGGGCATGAAGGCATTC
TGGCGGAGATCGTGGGCCGCGAACGCGTGCTCGCCGGCAAGACCTATGTGGGCGGCACGCAGCTGGCCGCTGGCCATGTC
ATCGTCGGCACCCGCGGCAAAGACACCCACATTGGCGAGCTGGACGGCCGCATCACCGGGCGCGTGCAGCGCATTGCCGA
CACCTTCAACCGTGCCGGGCTGGACACCACCGTCAGTGACAACATCATGGGCACGATCTGGGACAAGCTGCTGATCAACG
TGGCGACCGGTGCACTCACCGGCATCACGCGCCTGACGTATGGCCAGCTGTACCGGCAACCCGAGCTCGAGGCCTGTGGC
GTGGCGGCCGTGGCCGAGGCCATGACGGTGGCAGAAGCCAGCGGCATCCGCCTCAGCATCACCGACCCGCGCGATGCCTG
GCTCAAGGCCGGTGCCGGCCTGCCGGATGAATTCAAGACCTCGATGCTGCAGAGCCTGGAAAAGGGCTCGGTCACCGAGA
TCGATTTTGTCAACGGCTCGGTGGTGCGCTGGGGCGCCAAATGCGGCGTGCCCACGCCGGTCAACCAGGCGCTGGTGGCC
TGCATCAAGGGCATTGAGCTGGGCTTGCCCGGTTCATCGTCGCACTAA

Upstream 100 bases:

>100_bases
ACAGCTGGTCCAGCAACCGCAGCAGCCTGATGTCCAGAAGTTCGAGATCTTTGCTCATACCTTTATTGTGATGCGTAATG
GAATCTATTGGTGCTACTGC

Downstream 100 bases:

>100_bases
CCAACAAGGGAAATAACGAGTCATGGCATATTCGAACCAGGCATATGTCGAGCATGTCGCGGTGCGCGTCAGGGACATCC
AGTGGTACATCAACTTCTTC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDNMDGSVQNSRLDQEGVAVKICVLGAGALGCAIGGVLTEAGHEVWLINRNAEQVDAMNSRGLILRDDGADRAVQVHAAT
TAQGVNMDTGAVDLVIVLVKSFHTRQAMEAATSLLGPDTAVLSLQNGLGHEGILAEIVGRERVLAGKTYVGGTQLAAGHV
IVGTRGKDTHIGELDGRITGRVQRIADTFNRAGLDTTVSDNIMGTIWDKLLINVATGALTGITRLTYGQLYRQPELEACG
VAAVAEAMTVAEASGIRLSITDPRDAWLKAGAGLPDEFKTSMLQSLEKGSVTEIDFVNGSVVRWGAKCGVPTPVNQALVA
CIKGIELGLPGSSSH

Sequences:

>Translated_335_residues
MDNMDGSVQNSRLDQEGVAVKICVLGAGALGCAIGGVLTEAGHEVWLINRNAEQVDAMNSRGLILRDDGADRAVQVHAAT
TAQGVNMDTGAVDLVIVLVKSFHTRQAMEAATSLLGPDTAVLSLQNGLGHEGILAEIVGRERVLAGKTYVGGTQLAAGHV
IVGTRGKDTHIGELDGRITGRVQRIADTFNRAGLDTTVSDNIMGTIWDKLLINVATGALTGITRLTYGQLYRQPELEACG
VAAVAEAMTVAEASGIRLSITDPRDAWLKAGAGLPDEFKTSMLQSLEKGSVTEIDFVNGSVVRWGAKCGVPTPVNQALVA
CIKGIELGLPGSSSH
>Mature_335_residues
MDNMDGSVQNSRLDQEGVAVKICVLGAGALGCAIGGVLTEAGHEVWLINRNAEQVDAMNSRGLILRDDGADRAVQVHAAT
TAQGVNMDTGAVDLVIVLVKSFHTRQAMEAATSLLGPDTAVLSLQNGLGHEGILAEIVGRERVLAGKTYVGGTQLAAGHV
IVGTRGKDTHIGELDGRITGRVQRIADTFNRAGLDTTVSDNIMGTIWDKLLINVATGALTGITRLTYGQLYRQPELEACG
VAAVAEAMTVAEASGIRLSITDPRDAWLKAGAGLPDEFKTSMLQSLEKGSVTEIDFVNGSVVRWGAKCGVPTPVNQALVA
CIKGIELGLPGSSSH

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=312, Percent_Identity=27.8846153846154, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34958; Mature: 34958

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNMDGSVQNSRLDQEGVAVKICVLGAGALGCAIGGVLTEAGHEVWLINRNAEQVDAMNS
CCCCCCCCHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCC
RGLILRDDGADRAVQVHAATTAQGVNMDTGAVDLVIVLVKSFHTRQAMEAATSLLGPDTA
CCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLSLQNGLGHEGILAEIVGRERVLAGKTYVGGTQLAAGHVIVGTRGKDTHIGELDGRITG
EEEECCCCCCCCHHHHHHCCCCEEECCEEECCCEEECCEEEEECCCCCCCCCCCCCHHHH
RVQRIADTFNRAGLDTTVSDNIMGTIWDKLLINVATGALTGITRLTYGQLYRQPELEACG
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VAAVAEAMTVAEASGIRLSITDPRDAWLKAGAGLPDEFKTSMLQSLEKGSVTEIDFVNGS
HHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCC
VVRWGAKCGVPTPVNQALVACIKGIELGLPGSSSH
EEEECCCCCCCCCHHHHHHHHHHCCEECCCCCCCC
>Mature Secondary Structure
MDNMDGSVQNSRLDQEGVAVKICVLGAGALGCAIGGVLTEAGHEVWLINRNAEQVDAMNS
CCCCCCCCHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCHHHHHCCCC
RGLILRDDGADRAVQVHAATTAQGVNMDTGAVDLVIVLVKSFHTRQAMEAATSLLGPDTA
CCEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLSLQNGLGHEGILAEIVGRERVLAGKTYVGGTQLAAGHVIVGTRGKDTHIGELDGRITG
EEEECCCCCCCCHHHHHHCCCCEEECCEEECCCEEECCEEEEECCCCCCCCCCCCCHHHH
RVQRIADTFNRAGLDTTVSDNIMGTIWDKLLINVATGALTGITRLTYGQLYRQPELEACG
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VAAVAEAMTVAEASGIRLSITDPRDAWLKAGAGLPDEFKTSMLQSLEKGSVTEIDFVNGS
HHHHHHHHHHHHCCCCEEEECCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCCC
VVRWGAKCGVPTPVNQALVACIKGIELGLPGSSSH
EEEECCCCCCCCCHHHHHHHHHHCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]