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The map label for this gene is aroE [H]

Identifier: 91790327

GI number: 91790327

Start: 4749826

End: 4750659

Strand: Reverse

Name: aroE [H]

Synonym: Bpro_4495

Alternate gene names: 91790327

Gene position: 4750659-4749826 (Counterclockwise)

Preceding gene: 91790328

Following gene: 91790325

Centisome position: 91.35

GC content: 64.03

Gene sequence:

>834_bases
ATGATCAACGGCAACACCGAACTCATTGCCCACATCGGTTACCCCACGCATTCGTTCAAGGCGCCGATGATCTACAACCC
CTACTTTGACCACATCGGCGTCAATGCCCGGGTGATGCCCATGGGCTGCCAGAGCGCTGACTACCCGGCCTTTCTGCGCG
CGGTGTTCACGCTGACCAACATTCGGGGCGCCCTGATCACCATGCCGCACAAGGTCACCACGGTGGACCTGCTCGACCGC
GCCACGCCCACCGTGTCGGTGGCGGGCTCGTGCAACGCCGTGCGGCGCGGCGCCGATGGCAAGCTCGAAGGCGACATGTT
CGATGGCGAAGGCTTTGTGCGCGGTGTGCAGCGCAAGGGCCTGACGCTGGACGGTGCCCGGGTGCTGGTGGTCGGCAGCG
GTGGCGTGGGATCGGCGATTGCCGCATCGCTGGCGGCGGCCGGTATTGGCGCCATCAGCCTGCATGACGTGAACACCGCG
TCCTGCGAAGGCCTGGGCGCGCGGCTGAGAAAGCACTACCCCAGGTTGCAGGTCAGCACCATGTCCAATGACCCGGCCGG
CCACGACCTGGTGGTCAATGCCACGCCCATGGGAATGAACGAGGGCGACCCGATGCCCATGGACATTGCGCGCATCGCGC
CGACCACCTTTGTCGGCGAAGTCGTGATGAAGACAGAGATGACCGCTTTCCTCAATGCTGCGGAGGCACGCGGCTGCCCC
ATCCAGGTGGGTTCGGACATGCTGTTCGAGCAGATCCCGGCCTATCTTGAATTTTTTGGCTTCCCGACCACCACGCCCGA
GGTGCTGCGTTCCGTGGCGAAACTCAGTTACTGA

Upstream 100 bases:

>100_bases
GCAACCCGAATCATCCAGCGGTCACCATCCAACCCAATCCGATAACGACGCCCCAGCGACACCCCGGCGCACTCACCCCA
CTCACCATCAGGACACGCAC

Downstream 100 bases:

>100_bases
CCATCATGCGGCGTCCGGGCGCGCAGCGTCATCCGCGCGCAGCAGGCCATGGCGAATGGCAGGCGCTGACGGATTCGCCA
TCATGACGGCCCAGGGCAAC

Product: shikimate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MINGNTELIAHIGYPTHSFKAPMIYNPYFDHIGVNARVMPMGCQSADYPAFLRAVFTLTNIRGALITMPHKVTTVDLLDR
ATPTVSVAGSCNAVRRGADGKLEGDMFDGEGFVRGVQRKGLTLDGARVLVVGSGGVGSAIAASLAAAGIGAISLHDVNTA
SCEGLGARLRKHYPRLQVSTMSNDPAGHDLVVNATPMGMNEGDPMPMDIARIAPTTFVGEVVMKTEMTAFLNAAEARGCP
IQVGSDMLFEQIPAYLEFFGFPTTTPEVLRSVAKLSY

Sequences:

>Translated_277_residues
MINGNTELIAHIGYPTHSFKAPMIYNPYFDHIGVNARVMPMGCQSADYPAFLRAVFTLTNIRGALITMPHKVTTVDLLDR
ATPTVSVAGSCNAVRRGADGKLEGDMFDGEGFVRGVQRKGLTLDGARVLVVGSGGVGSAIAASLAAAGIGAISLHDVNTA
SCEGLGARLRKHYPRLQVSTMSNDPAGHDLVVNATPMGMNEGDPMPMDIARIAPTTFVGEVVMKTEMTAFLNAAEARGCP
IQVGSDMLFEQIPAYLEFFGFPTTTPEVLRSVAKLSY
>Mature_277_residues
MINGNTELIAHIGYPTHSFKAPMIYNPYFDHIGVNARVMPMGCQSADYPAFLRAVFTLTNIRGALITMPHKVTTVDLLDR
ATPTVSVAGSCNAVRRGADGKLEGDMFDGEGFVRGVQRKGLTLDGARVLVVGSGGVGSAIAASLAAAGIGAISLHDVNTA
SCEGLGARLRKHYPRLQVSTMSNDPAGHDLVVNATPMGMNEGDPMPMDIARIAPTTFVGEVVMKTEMTAFLNAAEARGCP
IQVGSDMLFEQIPAYLEFFGFPTTTPEVLRSVAKLSY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=262, Percent_Identity=25.9541984732824, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789675, Length=275, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29393; Mature: 29393

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINGNTELIAHIGYPTHSFKAPMIYNPYFDHIGVNARVMPMGCQSADYPAFLRAVFTLTN
CCCCCEEEEEEECCCCCCCCCCEEECCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
IRGALITMPHKVTTVDLLDRATPTVSVAGSCNAVRRGADGKLEGDMFDGEGFVRGVQRKG
CCEEEEECCCCEEEHHHHHCCCCCEEECCCCHHHHCCCCCCCCCCEECCCHHHHHHHHCC
LTLDGARVLVVGSGGVGSAIAASLAAAGIGAISLHDVNTASCEGLGARLRKHYPRLQVST
EEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEE
MSNDPAGHDLVVNATPMGMNEGDPMPMDIARIAPTTFVGEVVMKTEMTAFLNAAEARGCP
CCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
IQVGSDMLFEQIPAYLEFFGFPTTTPEVLRSVAKLSY
EEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MINGNTELIAHIGYPTHSFKAPMIYNPYFDHIGVNARVMPMGCQSADYPAFLRAVFTLTN
CCCCCEEEEEEECCCCCCCCCCEEECCCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
IRGALITMPHKVTTVDLLDRATPTVSVAGSCNAVRRGADGKLEGDMFDGEGFVRGVQRKG
CCEEEEECCCCEEEHHHHHCCCCCEEECCCCHHHHCCCCCCCCCCEECCCHHHHHHHHCC
LTLDGARVLVVGSGGVGSAIAASLAAAGIGAISLHDVNTASCEGLGARLRKHYPRLQVST
EEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEEE
MSNDPAGHDLVVNATPMGMNEGDPMPMDIARIAPTTFVGEVVMKTEMTAFLNAAEARGCP
CCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCC
IQVGSDMLFEQIPAYLEFFGFPTTTPEVLRSVAKLSY
EEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA