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The map label for this gene is gph [C]

Identifier: 91790295

GI number: 91790295

Start: 4715638

End: 4716390

Strand: Reverse

Name: gph [C]

Synonym: Bpro_4462

Alternate gene names: 91790295

Gene position: 4716390-4715638 (Counterclockwise)

Preceding gene: 91790296

Following gene: 91790293

Centisome position: 90.7

GC content: 65.07

Gene sequence:

>753_bases
ATGGCCGACCGCGCTTTTCACCTGGACCCCGGTGCTTTTGACGCCGCGATTGTCGATCTGGACGGCACCATGGTGGACAC
CGTGGGAGACTTTGTGGCCGCGCTCAACCTGATGCTGGCCGATCTGCCGGTCCCGGGCGGCGAAACCCGTCGGGTTGATG
CCGCCACGGTGGGCTCCATGGTCGGCAAGGGCTCTGAGCATCTGATCCGGTCCGTATTGAATCACCTCCAGGCCCAGGAC
AGCGGGATGTCACCCCCTGTTAATTCAGCAGAAAACTGCGACCGCGCCTATGCCGGCTACCAAGGGCACTATGACCGCAT
CAATGGCCTGCACTCGGCGGTTTACCCCGGTGTGCCGGAAGGGCTGCGGGTGCTGCAGCGGGCCGGGCTCAAGCTGGCCT
GCGTGACCAACAAACCGGCTGCCTTTGCGCGCGCGCTGATCGAACTCAAGGGGCTGGACGGTTTTTTCACCGAGGTGTTT
GGCGGGGATTCGTTCGAGCGCAAGAAGCCTGATCCGCTGCCTCTGCTGAAAACCTGCGAGGCCCTGGGAACCCGCCCGGA
CCGCACCTTGGTGATTGGCGACTCCAGCAATGATGCCCAGGCGGCCCGCGCGGCCGGTTGTCCCGTGGTGCTGGTCACCT
ACGGCTACAACCACGGCGAGCCGGTGCGCGCTGTGGATGCGGATGGGTTTATCGACTCGCTGGCGCAACTGCAGTTTGCA
ATGGCCGCCGTGGCGGGGGCGGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
CCGACTGGCTGGAAAAGCCGCTCGATGAGCAGCACATGCTCGACTGCCTGCGCCGGGCCGTCAGGAGCGGGCGAGCCCGC
CAATGAAAGGACTCTCTTTG

Downstream 100 bases:

>100_bases
ACGAGGCGGGGAATTCAGCCCCGCATTTAACGCCTTGCTTGAAGCCCTTGCGGCGCGCATTCCACCGGCCGACCCCGGAA
AGTGGTCAGCTTGGGTGACA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MADRAFHLDPGAFDAAIVDLDGTMVDTVGDFVAALNLMLADLPVPGGETRRVDAATVGSMVGKGSEHLIRSVLNHLQAQD
SGMSPPVNSAENCDRAYAGYQGHYDRINGLHSAVYPGVPEGLRVLQRAGLKLACVTNKPAAFARALIELKGLDGFFTEVF
GGDSFERKKPDPLPLLKTCEALGTRPDRTLVIGDSSNDAQAARAAGCPVVLVTYGYNHGEPVRAVDADGFIDSLAQLQFA
MAAVAGAASA

Sequences:

>Translated_250_residues
MADRAFHLDPGAFDAAIVDLDGTMVDTVGDFVAALNLMLADLPVPGGETRRVDAATVGSMVGKGSEHLIRSVLNHLQAQD
SGMSPPVNSAENCDRAYAGYQGHYDRINGLHSAVYPGVPEGLRVLQRAGLKLACVTNKPAAFARALIELKGLDGFFTEVF
GGDSFERKKPDPLPLLKTCEALGTRPDRTLVIGDSSNDAQAARAAGCPVVLVTYGYNHGEPVRAVDADGFIDSLAQLQFA
MAAVAGAASA
>Mature_249_residues
ADRAFHLDPGAFDAAIVDLDGTMVDTVGDFVAALNLMLADLPVPGGETRRVDAATVGSMVGKGSEHLIRSVLNHLQAQDS
GMSPPVNSAENCDRAYAGYQGHYDRINGLHSAVYPGVPEGLRVLQRAGLKLACVTNKPAAFARALIELKGLDGFFTEVFG
GDSFERKKPDPLPLLKTCEALGTRPDRTLVIGDSSNDAQAARAAGCPVVLVTYGYNHGEPVRAVDADGFIDSLAQLQFAM
AAVAGAASA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=229, Percent_Identity=35.3711790393013, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26182; Mature: 26051

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRAFHLDPGAFDAAIVDLDGTMVDTVGDFVAALNLMLADLPVPGGETRRVDAATVGSM
CCCCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHH
VGKGSEHLIRSVLNHLQAQDSGMSPPVNSAENCDRAYAGYQGHYDRINGLHSAVYPGVPE
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
GLRVLQRAGLKLACVTNKPAAFARALIELKGLDGFFTEVFGGDSFERKKPDPLPLLKTCE
HHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
ALGTRPDRTLVIGDSSNDAQAARAAGCPVVLVTYGYNHGEPVRAVDADGFIDSLAQLQFA
HHCCCCCCEEEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCEEECCCHHHHHHHHHHHH
MAAVAGAASA
HHHHHHCCCC
>Mature Secondary Structure 
ADRAFHLDPGAFDAAIVDLDGTMVDTVGDFVAALNLMLADLPVPGGETRRVDAATVGSM
CCCCEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHH
VGKGSEHLIRSVLNHLQAQDSGMSPPVNSAENCDRAYAGYQGHYDRINGLHSAVYPGVPE
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHH
GLRVLQRAGLKLACVTNKPAAFARALIELKGLDGFFTEVFGGDSFERKKPDPLPLLKTCE
HHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHH
ALGTRPDRTLVIGDSSNDAQAARAAGCPVVLVTYGYNHGEPVRAVDADGFIDSLAQLQFA
HHCCCCCCEEEEECCCCCHHHHHHCCCCEEEEEECCCCCCCCEEECCCHHHHHHHHHHHH
MAAVAGAASA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA