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The map label for this gene is mngR [H]

Identifier: 91789226

GI number: 91789226

Start: 3563872

End: 3564615

Strand: Direct

Name: mngR [H]

Synonym: Bpro_3370

Alternate gene names: 91789226

Gene position: 3563872-3564615 (Clockwise)

Preceding gene: 91789225

Following gene: 91789227

Centisome position: 68.53

GC content: 70.83

Gene sequence:

>744_bases
ATGGAAGCACCCCACCATCTGGCCCTGGTAGACAACTCCCCCGGTCTGCGCCGTTACGCGGCGCTGGCCAACGCGCTGCG
CGTGCGGGTGGTGGCGGGCGAATGGCCGCCGGGCAGCGCCCTGCCGGCCGAAACCCTGCTGGCGACAGAGCACCAGGTGG
CGCTGGGCACCATGCGGCGCGCGCTGGAGCTGCTGGTGGAACAGGGGCTGATAGAGCGCATCCACGGCAAGGGCACGTTT
GTGCGCCATGGCATTGCGGGGGGATCGATGCTGCGCTTCTTCCGCTTTGGCGGCGGCAGCAACGAAATACCGCATTCGCG
CATTCTGGGGCGGCACTGCGTGGCCGCCACCACGGCCGTCGCGCGCGAGCTGGGCGTGGGCCCGGGCGAGTCGGTGCTGC
GCCTGCACCGCCTGCGCCTGCTGGCGGGCCAGCCCTGCCTGCTGGAAGAGATGTGGCTTCCGCTGGACCTGTTTGCCCCC
CTGGCCGATGACGACCTGGCGCAGTGGGACGACCTGCTCTACCCCATGTTTGCCCGCCGCTGCGGCGTGCACGTGCACCG
CGCGGTGGACCAGATCGGCTTTGGCGTGCTGACGGGCCCGCAGGCCAGGCACCTGGCGCTGCCCGCAGGCCACCCCTGCG
TGACAGTGGAGCGCAGCGCGTTCGACCTGACGGGCCGTTGCGTGGAGTGGCGCACCACGCGGGGCGATGCCCACGCCTTT
CACTACACCGTGACCATCACCTGA

Upstream 100 bases:

>100_bases
TGTGCACCGCCGTTACCCCTCCTCACCTCTGCTTCGCCCGACACCCACTCAAGGGTATTCCCCCATCAACTAACTCCTAT
AGAGGACTATAGTTCTCGCC

Downstream 100 bases:

>100_bases
ACAAGCCACCTGAACAAGCCACCCAAACAAATCGCTTCAGCAAATCGCTTCAACAAACCGCTTCGACAAATCATTTGCGC
AAGACCGCAAAACACAGGAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEAPHHLALVDNSPGLRRYAALANALRVRVVAGEWPPGSALPAETLLATEHQVALGTMRRALELLVEQGLIERIHGKGTF
VRHGIAGGSMLRFFRFGGGSNEIPHSRILGRHCVAATTAVARELGVGPGESVLRLHRLRLLAGQPCLLEEMWLPLDLFAP
LADDDLAQWDDLLYPMFARRCGVHVHRAVDQIGFGVLTGPQARHLALPAGHPCVTVERSAFDLTGRCVEWRTTRGDAHAF
HYTVTIT

Sequences:

>Translated_247_residues
MEAPHHLALVDNSPGLRRYAALANALRVRVVAGEWPPGSALPAETLLATEHQVALGTMRRALELLVEQGLIERIHGKGTF
VRHGIAGGSMLRFFRFGGGSNEIPHSRILGRHCVAATTAVARELGVGPGESVLRLHRLRLLAGQPCLLEEMWLPLDLFAP
LADDDLAQWDDLLYPMFARRCGVHVHRAVDQIGFGVLTGPQARHLALPAGHPCVTVERSAFDLTGRCVEWRTTRGDAHAF
HYTVTIT
>Mature_247_residues
MEAPHHLALVDNSPGLRRYAALANALRVRVVAGEWPPGSALPAETLLATEHQVALGTMRRALELLVEQGLIERIHGKGTF
VRHGIAGGSMLRFFRFGGGSNEIPHSRILGRHCVAATTAVARELGVGPGESVLRLHRLRLLAGQPCLLEEMWLPLDLFAP
LADDDLAQWDDLLYPMFARRCGVHVHRAVDQIGFGVLTGPQARHLALPAGHPCVTVERSAFDLTGRCVEWRTTRGDAHAF
HYTVTIT

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=232, Percent_Identity=26.2931034482759, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI87082252, Length=213, Percent_Identity=25.8215962441315, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790118, Length=226, Percent_Identity=23.8938053097345, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27011; Mature: 27011

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAPHHLALVDNSPGLRRYAALANALRVRVVAGEWPPGSALPAETLLATEHQVALGTMRR
CCCCCEEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHCCHHHHHHHHHH
ALELLVEQGLIERIHGKGTFVRHGIAGGSMLRFFRFGGGSNEIPHSRILGRHCVAATTAV
HHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
ARELGVGPGESVLRLHRLRLLAGQPCLLEEMWLPLDLFAPLADDDLAQWDDLLYPMFARR
HHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
CGVHVHRAVDQIGFGVLTGPQARHLALPAGHPCVTVERSAFDLTGRCVEWRTTRGDAHAF
HCHHHHHHHHHHCCCEECCCCCCEEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCEEE
HYTVTIT
EEEEEEC
>Mature Secondary Structure
MEAPHHLALVDNSPGLRRYAALANALRVRVVAGEWPPGSALPAETLLATEHQVALGTMRR
CCCCCEEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHCCHHHHHHHHHH
ALELLVEQGLIERIHGKGTFVRHGIAGGSMLRFFRFGGGSNEIPHSRILGRHCVAATTAV
HHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHH
ARELGVGPGESVLRLHRLRLLAGQPCLLEEMWLPLDLFAPLADDDLAQWDDLLYPMFARR
HHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHH
CGVHVHRAVDQIGFGVLTGPQARHLALPAGHPCVTVERSAFDLTGRCVEWRTTRGDAHAF
HCHHHHHHHHHHCCCEECCCCCCEEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCEEE
HYTVTIT
EEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]