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The map label for this gene is mmgC [H]

Identifier: 91788874

GI number: 91788874

Start: 3174573

End: 3175742

Strand: Reverse

Name: mmgC [H]

Synonym: Bpro_3014

Alternate gene names: 91788874

Gene position: 3175742-3174573 (Counterclockwise)

Preceding gene: 91788877

Following gene: 91788873

Centisome position: 61.07

GC content: 62.31

Gene sequence:

>1170_bases
ATGATCGAACGCAGCCTCTTCAGCCCCGACCACGAATCCTTCCGGGATACCTTCCGCCGCTTCATGGATAAGGAGATTGC
GCCTTTTCATGCTCAATGGGAAGAGCAGGGTTATGTGGACCGCCAGGTCTGGAACAAGGCCGGCGACAACGGCTTTTTGT
GCATGACCATGCCCGAGGTGTACGGCGGCTCGGGCGCTGACAAGCTGTATTCCGTCGTGCAGATGGAGGAACTGGTGCGT
GGTGGCTTCTCCGGCATCGGCTACGGGCTGCACAGCGAAATCGTTGCGCCTTACATCCTGCATTACGGCACCAGCCTTCA
GAAGGAAACCTTCCTGCCGCAGCTGGCCAGCGGCCGTATGGTGGGCGCCATCGCCATGAGCGAGCCCGCCGCCGGCTCCG
ACCTGCAGGGCGTCAAGACCACCGCCATCAAGCAGTCCGACGGCAGCTATCTGCTCAACGGCAGCAAAACCTTTGTCACC
AACGGCTGGCATGCCGACCTGGTGATCGTGGTGGCCAAGACCAACCCGGCCGCCGGTGCCAAGGGGACCAGCCTGTTGCT
GGTGGAGCGCGGGATGCCCGGCTTTGAAGTCGGCAAGCGCCTGAAGAAACTCGGCCTGAAGGCGCAGGACACCTCCGAGC
TCTTCTTTCACGACGTGAAGGTGCCGGCCGGCCACCTGCTGGGCGGCGAGGCGCACGAGAACCGGGGATTTATCTGCCTG
ATGGAGCAGTTGCCGTGGGAGCGCCTGCAAATCGCCATCACGGCCGTGTCGGCGGCGCAGGCCGCCATCGACTGGACGCT
GGCCTATGTGAAGGAGCGCAAGGTCTTTGGCCAGCCCGTGGCCAGCTACCAGAACACACGCTACAAACTGGCCGAGCTGC
AGACCGAGGTGCAGGTGGCGCGGGTGTTCGTTGACAAATGCACCGAACTGGTAGCTGCGGACATGCTGGACACCGCGACC
GCCAGCATGGCCAAGTACTGGTGCAGCGATCTGCAGTGCAAGGTCATGGACGAATGCGTACAGCTCTTCGGTGGCTATGG
CTACATGTGGGAATACCCGATCACTCGCGCCTATGCCGATGCGCGCGTGCAGCGCATCTACGGCGGCACCAACGAGATCA
TGAAAGAGGTGATTTCGCGGTCCATGGGCCTGGGTGGAAAGCAGGCCTGA

Upstream 100 bases:

>100_bases
CTGTTGAAGTATATTCATTTCACAAAGCACCCGCTTTGCATAAATAGGATTCACGCAGACCCTACGGTGACCTCCCTTTG
ACGGCCAGACAGGTGACATC

Downstream 100 bases:

>100_bases
CGAGACAAATCTCGCGACCATGCTCCAAAGCCGGGCACCACAAAGGAGATCCTCGGGCGGATGACGGTGCCGACGGTCAG
CGTTTCAGCCGCGACCCAGC

Product: acyl-CoA dehydrogenase-like protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MIERSLFSPDHESFRDTFRRFMDKEIAPFHAQWEEQGYVDRQVWNKAGDNGFLCMTMPEVYGGSGADKLYSVVQMEELVR
GGFSGIGYGLHSEIVAPYILHYGTSLQKETFLPQLASGRMVGAIAMSEPAAGSDLQGVKTTAIKQSDGSYLLNGSKTFVT
NGWHADLVIVVAKTNPAAGAKGTSLLLVERGMPGFEVGKRLKKLGLKAQDTSELFFHDVKVPAGHLLGGEAHENRGFICL
MEQLPWERLQIAITAVSAAQAAIDWTLAYVKERKVFGQPVASYQNTRYKLAELQTEVQVARVFVDKCTELVAADMLDTAT
ASMAKYWCSDLQCKVMDECVQLFGGYGYMWEYPITRAYADARVQRIYGGTNEIMKEVISRSMGLGGKQA

Sequences:

>Translated_389_residues
MIERSLFSPDHESFRDTFRRFMDKEIAPFHAQWEEQGYVDRQVWNKAGDNGFLCMTMPEVYGGSGADKLYSVVQMEELVR
GGFSGIGYGLHSEIVAPYILHYGTSLQKETFLPQLASGRMVGAIAMSEPAAGSDLQGVKTTAIKQSDGSYLLNGSKTFVT
NGWHADLVIVVAKTNPAAGAKGTSLLLVERGMPGFEVGKRLKKLGLKAQDTSELFFHDVKVPAGHLLGGEAHENRGFICL
MEQLPWERLQIAITAVSAAQAAIDWTLAYVKERKVFGQPVASYQNTRYKLAELQTEVQVARVFVDKCTELVAADMLDTAT
ASMAKYWCSDLQCKVMDECVQLFGGYGYMWEYPITRAYADARVQRIYGGTNEIMKEVISRSMGLGGKQA
>Mature_389_residues
MIERSLFSPDHESFRDTFRRFMDKEIAPFHAQWEEQGYVDRQVWNKAGDNGFLCMTMPEVYGGSGADKLYSVVQMEELVR
GGFSGIGYGLHSEIVAPYILHYGTSLQKETFLPQLASGRMVGAIAMSEPAAGSDLQGVKTTAIKQSDGSYLLNGSKTFVT
NGWHADLVIVVAKTNPAAGAKGTSLLLVERGMPGFEVGKRLKKLGLKAQDTSELFFHDVKVPAGHLLGGEAHENRGFICL
MEQLPWERLQIAITAVSAAQAAIDWTLAYVKERKVFGQPVASYQNTRYKLAELQTEVQVARVFVDKCTELVAADMLDTAT
ASMAKYWCSDLQCKVMDECVQLFGGYGYMWEYPITRAYADARVQRIYGGTNEIMKEVISRSMGLGGKQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=53.1413612565445, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=36.0526315789474, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI226958414, Length=351, Percent_Identity=37.8917378917379, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=34.5945945945946, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI4501859, Length=377, Percent_Identity=32.3607427055703, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=32.3607427055703, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=30.6068601583113, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=30.6068601583113, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI76496475, Length=357, Percent_Identity=33.8935574229692, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4557235, Length=357, Percent_Identity=33.8935574229692, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI21361497, Length=362, Percent_Identity=29.0055248618785, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI4503943, Length=382, Percent_Identity=28.2722513089005, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=28.9325842696629, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI211971008, Length=290, Percent_Identity=26.551724137931, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI48976061, Length=290, Percent_Identity=26.551724137931, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI38505218, Length=381, Percent_Identity=25.4593175853018, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI87081958, Length=355, Percent_Identity=28.4507042253521, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786223, Length=335, Percent_Identity=27.1641791044776, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081702, Length=368, Percent_Identity=23.9130434782609, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082384, Length=268, Percent_Identity=28.3582089552239, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=387, Percent_Identity=34.3669250645995, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=35.7333333333333, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=32.5459317585302, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17508101, Length=375, Percent_Identity=30.4, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=32.1525885558583, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=31.496062992126, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17506239, Length=377, Percent_Identity=29.7082228116711, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17505929, Length=384, Percent_Identity=31.25, Blast_Score=181, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17551932, Length=385, Percent_Identity=31.1688311688312, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI71990804, Length=288, Percent_Identity=32.6388888888889, Blast_Score=161, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71985184, Length=361, Percent_Identity=30.4709141274238, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71985192, Length=318, Percent_Identity=31.4465408805031, Blast_Score=131, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=27.0833333333333, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=32.7510917030568, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=278, Percent_Identity=28.0575539568345, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17531909, Length=240, Percent_Identity=26.6666666666667, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562446, Length=299, Percent_Identity=27.0903010033445, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531913, Length=94, Percent_Identity=32.9787234042553, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355753, Length=378, Percent_Identity=35.4497354497354, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI21356377, Length=380, Percent_Identity=32.1052631578947, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24660351, Length=381, Percent_Identity=33.0708661417323, Blast_Score=195, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=33.0687830687831, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=29.4736842105263, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI281363737, Length=380, Percent_Identity=30.7894736842105, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI19920834, Length=391, Percent_Identity=27.8772378516624, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42998; Mature: 42998

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERSLFSPDHESFRDTFRRFMDKEIAPFHAQWEEQGYVDRQVWNKAGDNGFLCMTMPEV
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHCCCCCCEEEEECHHH
YGGSGADKLYSVVQMEELVRGGFSGIGYGLHSEIVAPYILHYGTSLQKETFLPQLASGRM
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCE
VGAIAMSEPAAGSDLQGVKTTAIKQSDGSYLLNGSKTFVTNGWHADLVIVVAKTNPAAGA
EEEEEECCCCCCCCCCCCCCEEEEECCCCEEECCCEEEEECCCCCEEEEEEEECCCCCCC
KGTSLLLVERGMPGFEVGKRLKKLGLKAQDTSELFFHDVKVPAGHLLGGEAHENRGFICL
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCEEEE
MEQLPWERLQIAITAVSAAQAAIDWTLAYVKERKVFGQPVASYQNTRYKLAELQTEVQVA
HHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHH
RVFVDKCTELVAADMLDTATASMAKYWCSDLQCKVMDECVQLFGGYGYMWEYPITRAYAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHH
ARVQRIYGGTNEIMKEVISRSMGLGGKQA
HHHHHHHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MIERSLFSPDHESFRDTFRRFMDKEIAPFHAQWEEQGYVDRQVWNKAGDNGFLCMTMPEV
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHCCCCCCEEEEECHHH
YGGSGADKLYSVVQMEELVRGGFSGIGYGLHSEIVAPYILHYGTSLQKETFLPQLASGRM
HCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCHHHHCCCE
VGAIAMSEPAAGSDLQGVKTTAIKQSDGSYLLNGSKTFVTNGWHADLVIVVAKTNPAAGA
EEEEEECCCCCCCCCCCCCCEEEEECCCCEEECCCEEEEECCCCCEEEEEEEECCCCCCC
KGTSLLLVERGMPGFEVGKRLKKLGLKAQDTSELFFHDVKVPAGHLLGGEAHENRGFICL
CCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCEEEE
MEQLPWERLQIAITAVSAAQAAIDWTLAYVKERKVFGQPVASYQNTRYKLAELQTEVQVA
HHHCCCCHHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHH
RVFVDKCTELVAADMLDTATASMAKYWCSDLQCKVMDECVQLFGGYGYMWEYPITRAYAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHH
ARVQRIYGGTNEIMKEVISRSMGLGGKQA
HHHHHHHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]