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The map label for this gene is nhaA1 [H]

Identifier: 91788225

GI number: 91788225

Start: 2453767

End: 2454306

Strand: Direct

Name: nhaA1 [H]

Synonym: Bpro_2358

Alternate gene names: 91788225

Gene position: 2453767-2454306 (Clockwise)

Preceding gene: 91788224

Following gene: 91788227

Centisome position: 47.19

GC content: 60.19

Gene sequence:

>540_bases
ATGAAAACCCGGGACTCGCTGCTAGCCCCTGACGGGGCAACCGATCACATCCGTGGCCAGTCGTTCGCCGCTGTCACGGT
GATTGAGTATGGCGATTTTGAATGCGCGCTATGCCTGCAGGCCTACGCGGGGCTGAAGGTGATGCTTCCGCATTTCGGAC
AGCAGTTGCGCTTTGTATTTCGCCACTTCCCGCTGCGGGAAATGCATCCGCACGCCGAACTGGCCGCGGAAGCGGCGGAA
GCGGCCGGCGCCCAGGGCAAGTTCTGGCCCATGTACGAACTGCTTTTCACGCACCAGCAACACCTGACGGAAAAGCACCT
GCTCGACTATGCCGAGCAGGTGGGCCTGGACATGCCGCGGTACCGGAACGAAATGAGAGACCATGTCTACCTGCAGCGCG
TGCAGGAGCACATACTGGGCGCAAGACACCTGGACATACGCTCGACCCCCGCCTTTTATGTCAATGGCGTGGTCACTGAT
GTTTCATTTGGCCTGCAGCACCTGCACGAGGCAATTGACAAGGTGCTGCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCGGCTGAGCCCCGCATTGATGCATTGATCATGGGGCTGCCCCTGGCGCATACTGCCTGAAAAATGCACAGATAAAGGC
GCACGTAAAAGGTGACTGCC

Downstream 100 bases:

>100_bases
CGCTCTTCGCAGCTCAGAGAGCAGGCGCCACCAGTGCGCCGGCCAGCGCGGCATTCCTGCTGTGCAAACGTCGTGCCTGC
AGTGTCGCGCCAATGAAGAA

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKTRDSLLAPDGATDHIRGQSFAAVTVIEYGDFECALCLQAYAGLKVMLPHFGQQLRFVFRHFPLREMHPHAELAAEAAE
AAGAQGKFWPMYELLFTHQQHLTEKHLLDYAEQVGLDMPRYRNEMRDHVYLQRVQEHILGARHLDIRSTPAFYVNGVVTD
VSFGLQHLHEAIDKVLLAA

Sequences:

>Translated_179_residues
MKTRDSLLAPDGATDHIRGQSFAAVTVIEYGDFECALCLQAYAGLKVMLPHFGQQLRFVFRHFPLREMHPHAELAAEAAE
AAGAQGKFWPMYELLFTHQQHLTEKHLLDYAEQVGLDMPRYRNEMRDHVYLQRVQEHILGARHLDIRSTPAFYVNGVVTD
VSFGLQHLHEAIDKVLLAA
>Mature_179_residues
MKTRDSLLAPDGATDHIRGQSFAAVTVIEYGDFECALCLQAYAGLKVMLPHFGQQLRFVFRHFPLREMHPHAELAAEAAE
AAGAQGKFWPMYELLFTHQQHLTEKHLLDYAEQVGLDMPRYRNEMRDHVYLQRVQEHILGARHLDIRSTPAFYVNGVVTD
VSFGLQHLHEAIDKVLLAA

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 20393; Mature: 20393

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRDSLLAPDGATDHIRGQSFAAVTVIEYGDFECALCLQAYAGLKVMLPHFGQQLRFVF
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
RHFPLREMHPHAELAAEAAEAAGAQGKFWPMYELLFTHQQHLTEKHLLDYAEQVGLDMPR
HHCCHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
YRNEMRDHVYLQRVQEHILGARHLDIRSTPAFYVNGVVTDVSFGLQHLHEAIDKVLLAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTRDSLLAPDGATDHIRGQSFAAVTVIEYGDFECALCLQAYAGLKVMLPHFGQQLRFVF
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
RHFPLREMHPHAELAAEAAEAAGAQGKFWPMYELLFTHQQHLTEKHLLDYAEQVGLDMPR
HHCCHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
YRNEMRDHVYLQRVQEHILGARHLDIRSTPAFYVNGVVTDVSFGLQHLHEAIDKVLLAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA