Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 91787234

GI number: 91787234

Start: 1378493

End: 1379395

Strand: Direct

Name: prpC [H]

Synonym: Bpro_1338

Alternate gene names: 91787234

Gene position: 1378493-1379395 (Clockwise)

Preceding gene: 91787233

Following gene: 91787235

Centisome position: 26.51

GC content: 62.24

Gene sequence:

>903_bases
ATGAAATTCTCCGTGTTTCAGGTCAGCCGCAAGGGCGGGCGCGAGAAGAACGAAGACCGCATGGGCTATTGCTACACGCG
CGAATCGGGCTTGTTCGTCCTGGCCGACGGCATGGGCGGCCACCCCGACGGCGAGGTGGCGGCCCAACTGGCACTGCAGA
CCATTTCCGCGCTGTACCAGCAGGAAGCCCGTCCCACGATCCCGGACACCACGGAGTTCCTGTCGACCGCCCTGATGGCG
GCCCATCACCAGATCATTCGCTATGCCAGCGAAAAAGGCATGCTTGACACGCCCCGCACCACTCTGGTGGCTGCCATTTT
GCAGGGCGACGGGGCAACGTGGGTGCATTGCGGTGACTCCCGCCTGTATGTCGTGCGCGATGGCGAACTGCTGACGCGCA
CCCGTGACCACTCCTACCTCGAACAGCAGAGTGCCGGCGTGATCAGGTTTGAGCGCATCAACCGCAACATCCTCTTTACC
TGCCTGGGCTCGCCGAGCAAGCCCGTCTTTGACATTGCGGGCCCCGTCACGCTGCAGCAGGGCGACAAGCTGCTGCTGTG
TTCTGACGGCCTGTGGGGCAGCCTGAGTGATGACGAAATTGTTCGGCAGCTGTCTGCCAAAGGCGTGTCCGATGCGGTGC
CAGACCTGGTGGAAAGCGCCTTGCGCGCCGGCGGAGAACAGAGCGACAACGTGACCGTTCTGGCCATGGAGTGGGAAACG
CCGGATGCGTTTGAATCCACCCGGGGTGTTTCTACCGACAGCATCATGGACGGGGTGTTCGCTTCCACCATTCAGGCCGG
CCTGATGGACACCGTGGTGGACGACCTTGACGAAGCCACGATCGAGAAATCGATCGCAGAAATCAACGAGGCCATCCGCC
GCTCGGCTGCCAAGAAAGCCTGA

Upstream 100 bases:

>100_bases
AACTCACCGTCAGCGAGAAGGTGCGCCTTCAGTTTGACAACATCGTGTCCGATACCAAAAAAACCGCGCGTAAGGCCACC
GGCTTTGCGACCAAATTCAA

Downstream 100 bases:

>100_bases
GTATCGGCGCGAAGGCCCGTGCGCCATTGAGCGGCTTTGAGCGTTCCATCGCGCTCTTTCACGCTTGTTACCTCTTTTTC
CTTCCTTTACTGCTTTTTCC

Product: protein serine/threonine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MKFSVFQVSRKGGREKNEDRMGYCYTRESGLFVLADGMGGHPDGEVAAQLALQTISALYQQEARPTIPDTTEFLSTALMA
AHHQIIRYASEKGMLDTPRTTLVAAILQGDGATWVHCGDSRLYVVRDGELLTRTRDHSYLEQQSAGVIRFERINRNILFT
CLGSPSKPVFDIAGPVTLQQGDKLLLCSDGLWGSLSDDEIVRQLSAKGVSDAVPDLVESALRAGGEQSDNVTVLAMEWET
PDAFESTRGVSTDSIMDGVFASTIQAGLMDTVVDDLDEATIEKSIAEINEAIRRSAAKKA

Sequences:

>Translated_300_residues
MKFSVFQVSRKGGREKNEDRMGYCYTRESGLFVLADGMGGHPDGEVAAQLALQTISALYQQEARPTIPDTTEFLSTALMA
AHHQIIRYASEKGMLDTPRTTLVAAILQGDGATWVHCGDSRLYVVRDGELLTRTRDHSYLEQQSAGVIRFERINRNILFT
CLGSPSKPVFDIAGPVTLQQGDKLLLCSDGLWGSLSDDEIVRQLSAKGVSDAVPDLVESALRAGGEQSDNVTVLAMEWET
PDAFESTRGVSTDSIMDGVFASTIQAGLMDTVVDDLDEATIEKSIAEINEAIRRSAAKKA
>Mature_300_residues
MKFSVFQVSRKGGREKNEDRMGYCYTRESGLFVLADGMGGHPDGEVAAQLALQTISALYQQEARPTIPDTTEFLSTALMA
AHHQIIRYASEKGMLDTPRTTLVAAILQGDGATWVHCGDSRLYVVRDGELLTRTRDHSYLEQQSAGVIRFERINRNILFT
CLGSPSKPVFDIAGPVTLQQGDKLLLCSDGLWGSLSDDEIVRQLSAKGVSDAVPDLVESALRAGGEQSDNVTVLAMEWET
PDAFESTRGVSTDSIMDGVFASTIQAGLMDTVVDDLDEATIEKSIAEINEAIRRSAAKKA

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 32622; Mature: 32622

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSVFQVSRKGGREKNEDRMGYCYTRESGLFVLADGMGGHPDGEVAAQLALQTISALYQ
CCCEEEEEHHHCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
QEARPTIPDTTEFLSTALMAAHHQIIRYASEKGMLDTPRTTLVAAILQGDGATWVHCGDS
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
RLYVVRDGELLTRTRDHSYLEQQSAGVIRFERINRNILFTCLGSPSKPVFDIAGPVTLQQ
EEEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCEEECCCCEEECC
GDKLLLCSDGLWGSLSDDEIVRQLSAKGVSDAVPDLVESALRAGGEQSDNVTVLAMEWET
CCEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
PDAFESTRGVSTDSIMDGVFASTIQAGLMDTVVDDLDEATIEKSIAEINEAIRRSAAKKA
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFSVFQVSRKGGREKNEDRMGYCYTRESGLFVLADGMGGHPDGEVAAQLALQTISALYQ
CCCEEEEEHHHCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
QEARPTIPDTTEFLSTALMAAHHQIIRYASEKGMLDTPRTTLVAAILQGDGATWVHCGDS
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
RLYVVRDGELLTRTRDHSYLEQQSAGVIRFERINRNILFTCLGSPSKPVFDIAGPVTLQQ
EEEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCEEECCCCEEECC
GDKLLLCSDGLWGSLSDDEIVRQLSAKGVSDAVPDLVESALRAGGEQSDNVTVLAMEWET
CCEEEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCC
PDAFESTRGVSTDSIMDGVFASTIQAGLMDTVVDDLDEATIEKSIAEINEAIRRSAAKKA
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]