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The map label for this gene is pcaI [H]

Identifier: 91787126

GI number: 91787126

Start: 1275027

End: 1275743

Strand: Direct

Name: pcaI [H]

Synonym: Bpro_1229

Alternate gene names: 91787126

Gene position: 1275027-1275743 (Clockwise)

Preceding gene: 91787124

Following gene: 91787127

Centisome position: 24.52

GC content: 63.18

Gene sequence:

>717_bases
ATGATCAACAAGATTGCCCGCTCCATCGCCGATGCGCTGGCGGACGTGAAAGACGGCTCAACCATTCTGATCGGGGGTTT
TGGCACCGCCGGCATTCCCAATGAGCTCATCGACGGCCTGATTGCGCAGGGCGCCAAAGACCTGACCGTGGTCAACAACA
ACGCGGGCAACGGCGAGACCGGGCTGGCGGCCCTGCTGAAGGCCGGGCGGGTGCGCAAAATCATCTGCAGCTTTCCGCGC
CAGGCCGACAGCCATGTGTTCGACGGGCTGTATCGCAGCGGCAAGCTGGAGCTGGAACTGGTGCCGCAGGGCAACCTGGC
CGAGCGGATTCGCGCTGCGGGAGCGGGCATAGGCGCATTTTTCTCGCCCACGGGCTACGGCACCGAGCTGGCCAAAAATT
CGGATGGCTCGGCCAAGGAAACACGCGAACTCAACGGCAAGCAGTACGTGCTGGAGATGCCGATTTACGGCGATGTGGCC
TTGATCAAGGCCGAACAGGGCGATCGCTGGGGCAACCTGACGTACCGCATGGCGGCGCGCAATTTTGGCCCGGTGATGGC
CACGGCCGCTGCAAAAACCGTGGCAACGGTGCACGAGATTGTCGAGCTCGGCGCGCTCAATCCGGAGCACATCGTGACGC
CCGGCATCTTCGTGCAGCAGATCGTGAAGATAGACCGCGTGGCGACCCAGGCCGGCGGCTTCAAAAACGTGGCCTGA

Upstream 100 bases:

>100_bases
GGACCGGAAACTCTGCTGGATTCGCGCCCGGTATGCCCGGTCACCTGGCTGTGCTGGCGTGTTGCCTGTTTCTGCCCTGT
TCCCTGCTGGAGACAATTGA

Downstream 100 bases:

>100_bases
ACCTGTTGTGATCATTTGCCATCATTGACCAGCCATCCGGACGGAGTAACCCATGACCTACCAGAAACGCACCAAAGACC
AGCTTGCCGCCCGTGTTGCG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MINKIARSIADALADVKDGSTILIGGFGTAGIPNELIDGLIAQGAKDLTVVNNNAGNGETGLAALLKAGRVRKIICSFPR
QADSHVFDGLYRSGKLELELVPQGNLAERIRAAGAGIGAFFSPTGYGTELAKNSDGSAKETRELNGKQYVLEMPIYGDVA
LIKAEQGDRWGNLTYRMAARNFGPVMATAAAKTVATVHEIVELGALNPEHIVTPGIFVQQIVKIDRVATQAGGFKNVA

Sequences:

>Translated_238_residues
MINKIARSIADALADVKDGSTILIGGFGTAGIPNELIDGLIAQGAKDLTVVNNNAGNGETGLAALLKAGRVRKIICSFPR
QADSHVFDGLYRSGKLELELVPQGNLAERIRAAGAGIGAFFSPTGYGTELAKNSDGSAKETRELNGKQYVLEMPIYGDVA
LIKAEQGDRWGNLTYRMAARNFGPVMATAAAKTVATVHEIVELGALNPEHIVTPGIFVQQIVKIDRVATQAGGFKNVA
>Mature_238_residues
MINKIARSIADALADVKDGSTILIGGFGTAGIPNELIDGLIAQGAKDLTVVNNNAGNGETGLAALLKAGRVRKIICSFPR
QADSHVFDGLYRSGKLELELVPQGNLAERIRAAGAGIGAFFSPTGYGTELAKNSDGSAKETRELNGKQYVLEMPIYGDVA
LIKAEQGDRWGNLTYRMAARNFGPVMATAAAKTVATVHEIVELGALNPEHIVTPGIFVQQIVKIDRVATQAGGFKNVA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=226, Percent_Identity=46.4601769911504, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI11545841, Length=226, Percent_Identity=44.6902654867257, Blast_Score=177, Evalue=7e-45,
Organism=Escherichia coli, GI1788551, Length=219, Percent_Identity=41.5525114155251, Blast_Score=174, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=43.4599156118143, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21358325, Length=233, Percent_Identity=45.9227467811159, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24655794, Length=233, Percent_Identity=45.9227467811159, Blast_Score=192, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 25046; Mature: 25046

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKIARSIADALADVKDGSTILIGGFGTAGIPNELIDGLIAQGAKDLTVVNNNAGNGET
CHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHH
GLAALLKAGRVRKIICSFPRQADSHVFDGLYRSGKLELELVPQGNLAERIRAAGAGIGAF
HHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCC
FSPTGYGTELAKNSDGSAKETRELNGKQYVLEMPIYGDVALIKAEQGDRWGNLTYRMAAR
CCCCCCCCHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEEEECC
NFGPVMATAAAKTVATVHEIVELGALNPEHIVTPGIFVQQIVKIDRVATQAGGFKNVA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MINKIARSIADALADVKDGSTILIGGFGTAGIPNELIDGLIAQGAKDLTVVNNNAGNGET
CHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHH
GLAALLKAGRVRKIICSFPRQADSHVFDGLYRSGKLELELVPQGNLAERIRAAGAGIGAF
HHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCC
FSPTGYGTELAKNSDGSAKETRELNGKQYVLEMPIYGDVALIKAEQGDRWGNLTYRMAAR
CCCCCCCCHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEEEECC
NFGPVMATAAAKTVATVHEIVELGALNPEHIVTPGIFVQQIVKIDRVATQAGGFKNVA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]