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The map label for this gene is btr [H]

Identifier: 91787067

GI number: 91787067

Start: 1212534

End: 1213358

Strand: Direct

Name: btr [H]

Synonym: Bpro_1170

Alternate gene names: 91787067

Gene position: 1212534-1213358 (Clockwise)

Preceding gene: 91787066

Following gene: 91787068

Centisome position: 23.32

GC content: 62.79

Gene sequence:

>825_bases
ATGTCAACCGCCACACTCATACGCACACAGGAGCGCACACAAGAGCGTACGCAGGAAACACCCGCCAGCGACCTGCGGGT
CATTCCGATTCGACAGGCCATGGGGGATGCGCAGGTCGCGCCTTTGGGGACACCCTGCTCCAGCTGCCACCTGTGCGATC
TGTGCCTGCCCTGCGGCATGACAGACGGCGACGTGGAGTGCCTGGACAGCCTGACGTTCGGGCGTCGCAAGGTCAAGGCC
GGCCAGACGCTCTTTGACGAGGGCGACCACTTTCAATTCATGTATGCCGTGCGCAGCGGCACCTTCAAGTCCAGCCTGAT
GCTGGCCGACGGCCGCGAGCAGATCAGTGGCTTCCACATGGCCGGTGAGCTGATTGGCCTGGACGGCGTGGCCTATGGCA
AGCATGCCAGCACCGCTACGGCGCTGGAGGATACCGAGGTCTGCGTCATTCCCTATGCGCAACTGACCCGGCTGGCCACC
GGCAACGCCAGCATGCAGAACATGGTCAGTCGCCTGATGAGCCGCGAGATCATCCGGGAACACAGCCTGATGCTGTTGCT
GGGCAGCATGAACGCCGAGGAACGGCTGGCGGCGTTTCTGCTGAACCTGTCGCAGCGCCTGAAGGCCCGCGGCTACTCGG
CCAGCGAATTTCACCTGAGGATGACGCGCGCCGAAATCGGTAGCTACCTGGGCATGAAACTGGAAACCGTCAGCCGCACA
TTCTCGGCCTTCCAGCAGCAGGGTTTGCTTGAAGTCGACAAGCGCCACATCCGCATCGTCAACCTGGACGGCCTGACGCG
GGTCTTCGAGATGCACCTGCACTGA

Upstream 100 bases:

>100_bases
TTCCTCGACAAAAGCACCGAATCCGATCAACTTGCCCAGGCTGTTGCGAGAGCATCGCAACACCCTGCGCATTGACGGCC
GTCTCATCAAGGGGAAAATC

Downstream 100 bases:

>100_bases
AGGCTGCATCGGTATGAAATACAAGGACTATTACGCCGCGCTGGGTGTGCCACGGGACGCCGACACCGAACAGATCAAGA
AGGCCTACCGCAAGCTGGCG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSTATLIRTQERTQERTQETPASDLRVIPIRQAMGDAQVAPLGTPCSSCHLCDLCLPCGMTDGDVECLDSLTFGRRKVKA
GQTLFDEGDHFQFMYAVRSGTFKSSLMLADGREQISGFHMAGELIGLDGVAYGKHASTATALEDTEVCVIPYAQLTRLAT
GNASMQNMVSRLMSREIIREHSLMLLLGSMNAEERLAAFLLNLSQRLKARGYSASEFHLRMTRAEIGSYLGMKLETVSRT
FSAFQQQGLLEVDKRHIRIVNLDGLTRVFEMHLH

Sequences:

>Translated_274_residues
MSTATLIRTQERTQERTQETPASDLRVIPIRQAMGDAQVAPLGTPCSSCHLCDLCLPCGMTDGDVECLDSLTFGRRKVKA
GQTLFDEGDHFQFMYAVRSGTFKSSLMLADGREQISGFHMAGELIGLDGVAYGKHASTATALEDTEVCVIPYAQLTRLAT
GNASMQNMVSRLMSREIIREHSLMLLLGSMNAEERLAAFLLNLSQRLKARGYSASEFHLRMTRAEIGSYLGMKLETVSRT
FSAFQQQGLLEVDKRHIRIVNLDGLTRVFEMHLH
>Mature_273_residues
STATLIRTQERTQERTQETPASDLRVIPIRQAMGDAQVAPLGTPCSSCHLCDLCLPCGMTDGDVECLDSLTFGRRKVKAG
QTLFDEGDHFQFMYAVRSGTFKSSLMLADGREQISGFHMAGELIGLDGVAYGKHASTATALEDTEVCVIPYAQLTRLATG
NASMQNMVSRLMSREIIREHSLMLLLGSMNAEERLAAFLLNLSQRLKARGYSASEFHLRMTRAEIGSYLGMKLETVSRTF
SAFQQQGLLEVDKRHIRIVNLDGLTRVFEMHLH

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=242, Percent_Identity=41.3223140495868, Blast_Score=203, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 30411; Mature: 30280

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATLIRTQERTQERTQETPASDLRVIPIRQAMGDAQVAPLGTPCSSCHLCDLCLPCGM
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCC
TDGDVECLDSLTFGRRKVKAGQTLFDEGDHFQFMYAVRSGTFKSSLMLADGREQISGFHM
CCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEEECCCCCHHEEEEECCHHHHHHHHH
AGELIGLDGVAYGKHASTATALEDTEVCVIPYAQLTRLATGNASMQNMVSRLMSREIIRE
HHHEECCCCCCCCCCCCCHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HSLMLLLGSMNAEERLAAFLLNLSQRLKARGYSASEFHLRMTRAEIGSYLGMKLETVSRT
HCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHCCHHHHHHHH
FSAFQQQGLLEVDKRHIRIVNLDGLTRVFEMHLH
HHHHHHCCCHHCCCCEEEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
STATLIRTQERTQERTQETPASDLRVIPIRQAMGDAQVAPLGTPCSSCHLCDLCLPCGM
CCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCC
TDGDVECLDSLTFGRRKVKAGQTLFDEGDHFQFMYAVRSGTFKSSLMLADGREQISGFHM
CCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEEEECCCCCHHEEEEECCHHHHHHHHH
AGELIGLDGVAYGKHASTATALEDTEVCVIPYAQLTRLATGNASMQNMVSRLMSREIIRE
HHHEECCCCCCCCCCCCCHHHCCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HSLMLLLGSMNAEERLAAFLLNLSQRLKARGYSASEFHLRMTRAEIGSYLGMKLETVSRT
HCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHHHHHHHHHHCCHHHHHHHH
FSAFQQQGLLEVDKRHIRIVNLDGLTRVFEMHLH
HHHHHHCCCHHCCCCEEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]