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The map label for this gene is uvrY [H]

Identifier: 91787064

GI number: 91787064

Start: 1210041

End: 1210682

Strand: Direct

Name: uvrY [H]

Synonym: Bpro_1167

Alternate gene names: 91787064

Gene position: 1210041-1210682 (Clockwise)

Preceding gene: 91787063

Following gene: 91787065

Centisome position: 23.27

GC content: 63.24

Gene sequence:

>642_bases
TTGATCAGGATCGTCATTGTGGATGACCACGCGATCGTGCGCGAAGGTCTCAAACGCATCATTTCCTCGGCCGACGACAT
GGAGGTGGCGGGCGAAGCCGCCAATGGCGCCGAGGCCATGCAGCGGGTGCGCGAACTGGCCTTCGACGTGCTGATGCTGG
ACCTGTCCATGCCGGGGCGCAGCGGCATGGAGTTGATCAAGCTGGTCCGTGCCGAGAAGCCCAAGCTGCGCATCCTGGTG
CTGAGCATGCACCAGGAGCTGCAGTACGCCGTGCGCGCCATCAAGTCCGGCGCCAGCGGTTACCTGACCAAGGAGAGCGC
CCCCGCGCAACTGGAGGAGGCCATCCGCAAGATCGCCGCCGGCGGCGCCTTCATCAGCGCGGAAGTGGCCGAGCAACTGG
CTCTGGGTGCCATGCCGGGCAGCGAGGCGCCCAGGCACGACTGTCTGTCCAACCGCGAATTCGAGGTGTTTCGCCTGGTG
GTCGACGGCATGACCCTGACCGATATCGCGGCCCAGCTCCATCTCTCGGTCAAAACGGTCAGCACGCACAAGGTCAACCT
GATGCACAAGATGGGCTTGCACAACCAGAGCGAGCTGATCCGCTATGCACTCAAACATGGCCTGACCGATCAGTTGGAGT
AA

Upstream 100 bases:

>100_bases
TCCAGCCAACCGTTGCCAACGGACGCGCCTTGCCGCTGCGCTCCGTGGTGTTTGCGATGGTGGTGACTTTGACGGTGGCG
GCAACCCGGGGAGCAGTTCA

Downstream 100 bases:

>100_bases
TTGTGAAGTTCCAATAGGTGGTTGCCCGCCAGGCGGGGGCGGGAGACTGGCAACTGAAATCTGCGGGGTGGTATTTCCGG
CTACGAGATGGAGATCGAGG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MIRIVIVDDHAIVREGLKRIISSADDMEVAGEAANGAEAMQRVRELAFDVLMLDLSMPGRSGMELIKLVRAEKPKLRILV
LSMHQELQYAVRAIKSGASGYLTKESAPAQLEEAIRKIAAGGAFISAEVAEQLALGAMPGSEAPRHDCLSNREFEVFRLV
VDGMTLTDIAAQLHLSVKTVSTHKVNLMHKMGLHNQSELIRYALKHGLTDQLE

Sequences:

>Translated_213_residues
MIRIVIVDDHAIVREGLKRIISSADDMEVAGEAANGAEAMQRVRELAFDVLMLDLSMPGRSGMELIKLVRAEKPKLRILV
LSMHQELQYAVRAIKSGASGYLTKESAPAQLEEAIRKIAAGGAFISAEVAEQLALGAMPGSEAPRHDCLSNREFEVFRLV
VDGMTLTDIAAQLHLSVKTVSTHKVNLMHKMGLHNQSELIRYALKHGLTDQLE
>Mature_213_residues
MIRIVIVDDHAIVREGLKRIISSADDMEVAGEAANGAEAMQRVRELAFDVLMLDLSMPGRSGMELIKLVRAEKPKLRILV
LSMHQELQYAVRAIKSGASGYLTKESAPAQLEEAIRKIAAGGAFISAEVAEQLALGAMPGSEAPRHDCLSNREFEVFRLV
VDGMTLTDIAAQLHLSVKTVSTHKVNLMHKMGLHNQSELIRYALKHGLTDQLE

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=33.6492890995261, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=35.6435643564356, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786747, Length=200, Percent_Identity=29.5, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=32.8205128205128, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=31.3725490196078, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788712, Length=202, Percent_Identity=27.2277227722772, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=34.0659340659341, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082052, Length=118, Percent_Identity=33.0508474576271, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=33.0357142857143, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23364; Mature: 23364

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIVIVDDHAIVREGLKRIISSADDMEVAGEAANGAEAMQRVRELAFDVLMLDLSMPGR
CEEEEEECCHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
SGMELIKLVRAEKPKLRILVLSMHQELQYAVRAIKSGASGYLTKESAPAQLEEAIRKIAA
CHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHC
GGAFISAEVAEQLALGAMPGSEAPRHDCLSNREFEVFRLVVDGMTLTDIAAQLHLSVKTV
CCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHEEEC
STHKVNLMHKMGLHNQSELIRYALKHGLTDQLE
CHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRIVIVDDHAIVREGLKRIISSADDMEVAGEAANGAEAMQRVRELAFDVLMLDLSMPGR
CEEEEEECCHHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
SGMELIKLVRAEKPKLRILVLSMHQELQYAVRAIKSGASGYLTKESAPAQLEEAIRKIAA
CHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHHC
GGAFISAEVAEQLALGAMPGSEAPRHDCLSNREFEVFRLVVDGMTLTDIAAQLHLSVKTV
CCCHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHEEEC
STHKVNLMHKMGLHNQSELIRYALKHGLTDQLE
CHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]