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The map label for this gene is ffh [H]

Identifier: 91787012

GI number: 91787012

Start: 1148383

End: 1149741

Strand: Direct

Name: ffh [H]

Synonym: Bpro_1114

Alternate gene names: 91787012

Gene position: 1148383-1149741 (Clockwise)

Preceding gene: 91787006

Following gene: 91787024

Centisome position: 22.08

GC content: 63.65

Gene sequence:

>1359_bases
ATGGCCTCAGCCCTTACCGACAAACTCTCCCGCCTCGTCAAGGAAATGCGAGGCCAGGCCCGCATCACCGAATCCAATGT
GCAGGACATGTTGCGCGAGGTGCGCATGGCGCTGCTCGAAGCCGACGTGGCCCTGCCGGTGGTGCGCGACTTCATCGCCC
GCGTCAAGGACAAGGCCCTTGGCCAGGAGGTGATGGGTTCGCTGTCTCCCGGCCAGGCCCTGGTGGGCATCGTCAACCGC
GAGCTGGCGGCGACCATGGGCGAGGGCGTCAGCGACATCAACCTGGCGGCGCAACCGCCCGCGGTGATCCTGATGGCCGG
CCTGCAGGGCGCGGGCAAGACCACCACCACGGCCAAGCTGGCCAAGCACCTGATTGAAAAGCGCAAGAAAAAAGTCCTGA
CGGTGTCCGGCGACGTCTACCGGCCTGCCGCCATAGAGCAGCTCAAGACCGTGACGGCGCAGGCCGGTGCCGAATGGTTC
CCGAGCACGCCCGACCAGAAGCCCGTCGACATTGCCAAGGCCGCGATCGACTACGCACGCAGGCATTTCTTTGACGTGCT
GCTCGTCGACACGGCCGGCCGCCTGGCCATTGACGAAGCCCTGATGAAGGAAATCAGGGAGTTGCACGCGGCGCTCAACC
CGGTTGAAACGCTGTTCGTCGTCGATGCCATGCAGGGGCAGGACGCGGTCAACACGGCCAAGGCCTTCAAGGAAGCGTTG
CCGCTGACCGGCATCATTCTGACCAAGACTGACGGCGACTCGCGCGGCGGTGCGGCCCTGAGCGTGCGGCAGATCACCGG
CGCACCGATCAAGTTCTCCGGCACCAGCGAGAAAATCGACGGCCTGGAGGTGTTTGATGCCGAGCGGCATGCCGGCCGCA
TCCTGGGCATGGGTGACATCGTCGCGCTGGTCGAACAGGTCGCGGCAGGCGTTGATGTGGCTGCGGCGCAAAAGCTGGCC
GCCAAGATCAAGTCGGGCGATGGTTTTGACCTGAATGATTTCCTGAGCCAGCTCCAGCAGATGAAAAACATGGGCGGCTT
GTCCAGCCTGCTCGAGAAGCTGCCGGCGCAGATGGCTGCCAAGGCCGGTCAGGTGGACATGGACAAGGCTGAACGCGACA
TCAAGCGCAAGGAAGGCATCATCCAGAGCATGACGCCGCTGGAGCGCCGCAAGCCCGAACTCATCAAGGCCACCCGCAAG
CGCCGCATCGCGGCCGGCTCGGGCGTGCAGGTTCAGGAGGTCAACCGCCTGCTCAACGAGTTTGAGCAGATGCAGGGCAT
GATGAAAAAGATGAAGGGCAGCGGCATGATGAAGATGATGAAGCGCATGGGCGGCATGAAGGGCATGCCGAAGTTCTGA

Upstream 100 bases:

>100_bases
ACGCACTGAAAGCTAAAATCATGGCTACAGTTTAGCCCGTAGTGCTTTCTTTCCTCTCCTCTTTCCTTTCCTAATTGCTC
CATGTTTGTGGAGCCTGCTC

Downstream 100 bases:

>100_bases
CGCTCCGGGCTTGAGCCGGGTTTATATAAAAACGCCGCTAGGCCAATGAGTAAAAACGTCACCAGCTATCGTAAAGATAG
CTGGGTGCCGCCGGTCCGGT

Product: signal recognition particle subunit FFH/SRP54 (srp54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MASALTDKLSRLVKEMRGQARITESNVQDMLREVRMALLEADVALPVVRDFIARVKDKALGQEVMGSLSPGQALVGIVNR
ELAATMGEGVSDINLAAQPPAVILMAGLQGAGKTTTTAKLAKHLIEKRKKKVLTVSGDVYRPAAIEQLKTVTAQAGAEWF
PSTPDQKPVDIAKAAIDYARRHFFDVLLVDTAGRLAIDEALMKEIRELHAALNPVETLFVVDAMQGQDAVNTAKAFKEAL
PLTGIILTKTDGDSRGGAALSVRQITGAPIKFSGTSEKIDGLEVFDAERHAGRILGMGDIVALVEQVAAGVDVAAAQKLA
AKIKSGDGFDLNDFLSQLQQMKNMGGLSSLLEKLPAQMAAKAGQVDMDKAERDIKRKEGIIQSMTPLERRKPELIKATRK
RRIAAGSGVQVQEVNRLLNEFEQMQGMMKKMKGSGMMKMMKRMGGMKGMPKF

Sequences:

>Translated_452_residues
MASALTDKLSRLVKEMRGQARITESNVQDMLREVRMALLEADVALPVVRDFIARVKDKALGQEVMGSLSPGQALVGIVNR
ELAATMGEGVSDINLAAQPPAVILMAGLQGAGKTTTTAKLAKHLIEKRKKKVLTVSGDVYRPAAIEQLKTVTAQAGAEWF
PSTPDQKPVDIAKAAIDYARRHFFDVLLVDTAGRLAIDEALMKEIRELHAALNPVETLFVVDAMQGQDAVNTAKAFKEAL
PLTGIILTKTDGDSRGGAALSVRQITGAPIKFSGTSEKIDGLEVFDAERHAGRILGMGDIVALVEQVAAGVDVAAAQKLA
AKIKSGDGFDLNDFLSQLQQMKNMGGLSSLLEKLPAQMAAKAGQVDMDKAERDIKRKEGIIQSMTPLERRKPELIKATRK
RRIAAGSGVQVQEVNRLLNEFEQMQGMMKKMKGSGMMKMMKRMGGMKGMPKF
>Mature_451_residues
ASALTDKLSRLVKEMRGQARITESNVQDMLREVRMALLEADVALPVVRDFIARVKDKALGQEVMGSLSPGQALVGIVNRE
LAATMGEGVSDINLAAQPPAVILMAGLQGAGKTTTTAKLAKHLIEKRKKKVLTVSGDVYRPAAIEQLKTVTAQAGAEWFP
STPDQKPVDIAKAAIDYARRHFFDVLLVDTAGRLAIDEALMKEIRELHAALNPVETLFVVDAMQGQDAVNTAKAFKEALP
LTGIILTKTDGDSRGGAALSVRQITGAPIKFSGTSEKIDGLEVFDAERHAGRILGMGDIVALVEQVAAGVDVAAAQKLAA
KIKSGDGFDLNDFLSQLQQMKNMGGLSSLLEKLPAQMAAKAGQVDMDKAERDIKRKEGIIQSMTPLERRKPELIKATRKR
RIAAGSGVQVQEVNRLLNEFEQMQGMMKKMKGSGMMKMMKRMGGMKGMPKF

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=449, Percent_Identity=30.7349665924276, Blast_Score=202, Evalue=6e-52,
Organism=Homo sapiens, GI226371618, Length=379, Percent_Identity=31.3984168865435, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI295424842, Length=310, Percent_Identity=30, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI23308697, Length=310, Percent_Identity=30, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI89061728, Length=146, Percent_Identity=36.986301369863, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788963, Length=429, Percent_Identity=64.3356643356643, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1789874, Length=257, Percent_Identity=35.408560311284, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=415, Percent_Identity=30.3614457831325, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI193206261, Length=201, Percent_Identity=37.3134328358209, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6325345, Length=458, Percent_Identity=32.0960698689956, Blast_Score=189, Evalue=7e-49,
Organism=Drosophila melanogaster, GI17647949, Length=427, Percent_Identity=32.5526932084309, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24641198, Length=202, Percent_Identity=35.1485148514851, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 48816; Mature: 48685

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASALTDKLSRLVKEMRGQARITESNVQDMLREVRMALLEADVALPVVRDFIARVKDKAL
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVMGSLSPGQALVGIVNRELAATMGEGVSDINLAAQPPAVILMAGLQGAGKTTTTAKL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHH
AKHLIEKRKKKVLTVSGDVYRPAAIEQLKTVTAQAGAEWFPSTPDQKPVDIAKAAIDYAR
HHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RHFFDVLLVDTAGRLAIDEALMKEIRELHAALNPVETLFVVDAMQGQDAVNTAKAFKEAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHC
PLTGIILTKTDGDSRGGAALSVRQITGAPIKFSGTSEKIDGLEVFDAERHAGRILGMGDI
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCHHCCCHHHCCCCCCHHHH
VALVEQVAAGVDVAAAQKLAAKIKSGDGFDLNDFLSQLQQMKNMGGLSSLLEKLPAQMAA
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KAGQVDMDKAERDIKRKEGIIQSMTPLERRKPELIKATRKRRIAAGSGVQVQEVNRLLNE
HCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FEQMQGMMKKMKGSGMMKMMKRMGGMKGMPKF
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASALTDKLSRLVKEMRGQARITESNVQDMLREVRMALLEADVALPVVRDFIARVKDKAL
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVMGSLSPGQALVGIVNRELAATMGEGVSDINLAAQPPAVILMAGLQGAGKTTTTAKL
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHH
AKHLIEKRKKKVLTVSGDVYRPAAIEQLKTVTAQAGAEWFPSTPDQKPVDIAKAAIDYAR
HHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
RHFFDVLLVDTAGRLAIDEALMKEIRELHAALNPVETLFVVDAMQGQDAVNTAKAFKEAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHC
PLTGIILTKTDGDSRGGAALSVRQITGAPIKFSGTSEKIDGLEVFDAERHAGRILGMGDI
CCCEEEEEECCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCHHCCCHHHCCCCCCHHHH
VALVEQVAAGVDVAAAQKLAAKIKSGDGFDLNDFLSQLQQMKNMGGLSSLLEKLPAQMAA
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KAGQVDMDKAERDIKRKEGIIQSMTPLERRKPELIKATRKRRIAAGSGVQVQEVNRLLNE
HCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FEQMQGMMKKMKGSGMMKMMKRMGGMKGMPKF
HHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]