Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 91786989

GI number: 91786989

Start: 1124185

End: 1125339

Strand: Direct

Name: mrdB [H]

Synonym: Bpro_1091

Alternate gene names: 91786989

Gene position: 1124185-1125339 (Clockwise)

Preceding gene: 91786980

Following gene: 91786990

Centisome position: 21.62

GC content: 61.82

Gene sequence:

>1155_bases
ATGGCCGCCGTTTTCGACAAACCCTCACTTTTCCAGCGAACCGCCCCCCTGCTGCAGGGTTTTGACGGCCCCCTGGCCTT
TGCGGTCTTTTTGCTGGCCTGTGCCGGCCTGTTGATCATGTATTCCTCCGGCTACGACCATGGCAGCCGCTTTGCTGACC
ATGGCCGCAACATGCTGATTGCCGGGGGCATCATGTTTGTGGTGGCGCAGATCCCGCCACAGCGCCTGATGGCATTCGCC
GTCCCGCTCTATGTAGTCGGCGTGGGCCTGCTGGTGGCGGTCGCCATCTTTGGTGTCACCAAAAAGGGCGCGCGTCGCTG
GCTCAATGTCGGGGTGGTGATCCAGCCCAGTGAAATCCTGAAGATCGCGATGCCGCTGATGCTGGCCTGGTGGTTCCAGA
AGCGCGAAGGGCAGCTCAGGCCGCTGGATTTTCTGGCGGCCGGCCTGTTGCTGGCACTACCCGTCGGGCTCATCATGAAG
CAGCCTGACCTGGGGACCTCCCTGCTGGTGCTGGCTGCAGGTCTGGCGGTGATTTTTTTCGCCGGCCTGAGCTGGAAACT
GATTGTTCCTCCGGTGCTGCTGGGCCTGGTGGGTGTTTTCCTTGTGGTGTGGTTCGAGCCGCAACTGTGCGCCGACGGTG
TGCGCTGGCCCATCCTGCATGACTACCAGCAGCAGCGCATCTGCACGCTGCTCGATCCGTCGCGCGACCCGCTGGGCAAA
GGCTTTCACATCATCCAGGGCATGATTGCCATTGGCTCGGGTGGCGTGTTCGGCAAGGGCTTCATGGCCGGCACGCAGAC
GCACCTGGAGTTCATCCCCGAGCGCACCACCGACTTTATTTTTGCCGCCTATTCCGAAGAGTTCGGCCTGGCTGGCAACC
TGCTGCTCATCGCCGGTTTTATCTTCCTGATCCTGCGCGGGCTGGCCATTGCCCTGGAGGCCTCCACGCTGTTTGCGCGC
CTGCTGGCCGGTGCGCTGACGATGATTTTTTTCACCTACGCGTTTGTCAACATGGGTATGGTCAGCGGCATCCTGCCGGT
CGTGGGGGTTCCGCTGCCCTTTATCAGTTATGGCGGCACCGCCATGGTGACGCTGGGCCTGGCCCTCGGCATATTGATGT
CGATTGCCAAGGCCAAACGGCTGGTGCAGACCTGA

Upstream 100 bases:

>100_bases
TCAATGAAGGAATAGTTAGCTATTGTATTGATAGCTAAACAGGGTGAACCCAATCAGCTTCCTGTGCCTGGTGGCATGGA
AGCTGGCAGATAATCGGTGC

Downstream 100 bases:

>100_bases
CTGCCTTGAAGGCAAGGATTGGCTGTGTCAAGTAACAGGCGGGGCTTGCCTTCAAGCGACTTGCCGCGTACAAAGGCGCT
GGTTAGCTGGATTCCCCCTC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MAAVFDKPSLFQRTAPLLQGFDGPLAFAVFLLACAGLLIMYSSGYDHGSRFADHGRNMLIAGGIMFVVAQIPPQRLMAFA
VPLYVVGVGLLVAVAIFGVTKKGARRWLNVGVVIQPSEILKIAMPLMLAWWFQKREGQLRPLDFLAAGLLLALPVGLIMK
QPDLGTSLLVLAAGLAVIFFAGLSWKLIVPPVLLGLVGVFLVVWFEPQLCADGVRWPILHDYQQQRICTLLDPSRDPLGK
GFHIIQGMIAIGSGGVFGKGFMAGTQTHLEFIPERTTDFIFAAYSEEFGLAGNLLLIAGFIFLILRGLAIALEASTLFAR
LLAGALTMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTAMVTLGLALGILMSIAKAKRLVQT

Sequences:

>Translated_384_residues
MAAVFDKPSLFQRTAPLLQGFDGPLAFAVFLLACAGLLIMYSSGYDHGSRFADHGRNMLIAGGIMFVVAQIPPQRLMAFA
VPLYVVGVGLLVAVAIFGVTKKGARRWLNVGVVIQPSEILKIAMPLMLAWWFQKREGQLRPLDFLAAGLLLALPVGLIMK
QPDLGTSLLVLAAGLAVIFFAGLSWKLIVPPVLLGLVGVFLVVWFEPQLCADGVRWPILHDYQQQRICTLLDPSRDPLGK
GFHIIQGMIAIGSGGVFGKGFMAGTQTHLEFIPERTTDFIFAAYSEEFGLAGNLLLIAGFIFLILRGLAIALEASTLFAR
LLAGALTMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTAMVTLGLALGILMSIAKAKRLVQT
>Mature_383_residues
AAVFDKPSLFQRTAPLLQGFDGPLAFAVFLLACAGLLIMYSSGYDHGSRFADHGRNMLIAGGIMFVVAQIPPQRLMAFAV
PLYVVGVGLLVAVAIFGVTKKGARRWLNVGVVIQPSEILKIAMPLMLAWWFQKREGQLRPLDFLAAGLLLALPVGLIMKQ
PDLGTSLLVLAAGLAVIFFAGLSWKLIVPPVLLGLVGVFLVVWFEPQLCADGVRWPILHDYQQQRICTLLDPSRDPLGKG
FHIIQGMIAIGSGGVFGKGFMAGTQTHLEFIPERTTDFIFAAYSEEFGLAGNLLLIAGFIFLILRGLAIALEASTLFARL
LAGALTMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGTAMVTLGLALGILMSIAKAKRLVQT

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=357, Percent_Identity=49.859943977591, Blast_Score=277, Evalue=8e-76,
Organism=Escherichia coli, GI1786277, Length=377, Percent_Identity=28.3819628647215, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41295; Mature: 41164

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVFDKPSLFQRTAPLLQGFDGPLAFAVFLLACAGLLIMYSSGYDHGSRFADHGRNMLI
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEE
AGGIMFVVAQIPPQRLMAFAVPLYVVGVGLLVAVAIFGVTKKGARRWLNVGVVIQPSEIL
ECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEECHHHHH
KIAMPLMLAWWFQKREGQLRPLDFLAAGLLLALPVGLIMKQPDLGTSLLVLAAGLAVIFF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGLSWKLIVPPVLLGLVGVFLVVWFEPQLCADGVRWPILHDYQQQRICTLLDPSRDPLGK
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GFHIIQGMIAIGSGGVFGKGFMAGTQTHLEFIPERTTDFIFAAYSEEFGLAGNLLLIAGF
CHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHCCCCHHHEEEECCCCCCCCCHHHHHHHH
IFLILRGLAIALEASTLFARLLAGALTMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCH
AMVTLGLALGILMSIAKAKRLVQT
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAVFDKPSLFQRTAPLLQGFDGPLAFAVFLLACAGLLIMYSSGYDHGSRFADHGRNMLI
CCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEE
AGGIMFVVAQIPPQRLMAFAVPLYVVGVGLLVAVAIFGVTKKGARRWLNVGVVIQPSEIL
ECHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEECHHHHH
KIAMPLMLAWWFQKREGQLRPLDFLAAGLLLALPVGLIMKQPDLGTSLLVLAAGLAVIFF
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGLSWKLIVPPVLLGLVGVFLVVWFEPQLCADGVRWPILHDYQQQRICTLLDPSRDPLGK
HCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
GFHIIQGMIAIGSGGVFGKGFMAGTQTHLEFIPERTTDFIFAAYSEEFGLAGNLLLIAGF
CHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHCCCCHHHEEEECCCCCCCCCHHHHHHHH
IFLILRGLAIALEASTLFARLLAGALTMIFFTYAFVNMGMVSGILPVVGVPLPFISYGGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCH
AMVTLGLALGILMSIAKAKRLVQT
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]