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The map label for this gene is apxIIC [H]

Identifier: 91786922

GI number: 91786922

Start: 1049850

End: 1050329

Strand: Direct

Name: apxIIC [H]

Synonym: Bpro_1023

Alternate gene names: 91786922

Gene position: 1049850-1050329 (Clockwise)

Preceding gene: 91786921

Following gene: 91786923

Centisome position: 20.19

GC content: 59.58

Gene sequence:

>480_bases
ATGGCTCCGGAGGAGCTGGCAGCGCTGGCTGAGCTTGCCAAAAAGCAGGCGCACAAGGTGCTTGCGAAGGTTCCGCTATT
GGGTCCCGTGGCATGGCTGATGATGCAACAGGCCACCAGCCGGCACACGCTGCTCAGCGAACTGGAATGGCGTGTCATGC
CGGCGCTGGTCCTCGACCAGGCAAAGCTTTACCTGAAGGACGAGGCACCCGTGGCATTTGTCTCGTGGGCGCGACTCAGC
GATGCGGTGGTGCAACGCTACAAAACGGCTCCCCATCAACTCACTGCCGCAGACTGGGTCTCGGGTGATCAGATATGGTT
GATCGATGTGTTCACGCCATTTGGTGGTGCGCAGGATGTACTCAAGGATTTGCGCGAGAAGGTGTTTGCCGGGCAGGTCG
TGCACCAGTTGGTGCCGACCGCTCCTGCACTAGCCAAAGTATTGACTTGGCCCGCGGTATTCCCCACGGCAAGTACATGA

Upstream 100 bases:

>100_bases
ATTTGCAAGCCATCAATGATCTATTGGAAACAGAAAAACCATGACGAAGACATCGCCACCATCCACGCAGCTTCCTGCCG
GCTCCGGGGAAGCTAACCCC

Downstream 100 bases:

>100_bases
TCAGGATTGGCGCGTATAGCCGGTTTTTCTTCTAGTGGTAGCGACCGGTGCGACAATTCAAGCCATGACTTCAGCCATCA
GCACCCCGGTTTCCACCCTG

Product: RTX toxin-activating protein C

Products: NA

Alternate protein names: APX-IIC; Cytolysin IIC; CLY-IIC; HLY-IIC; RTX-II toxin determinant C; Toxin RTX-II-activating protein C [H]

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MAPEELAALAELAKKQAHKVLAKVPLLGPVAWLMMQQATSRHTLLSELEWRVMPALVLDQAKLYLKDEAPVAFVSWARLS
DAVVQRYKTAPHQLTAADWVSGDQIWLIDVFTPFGGAQDVLKDLREKVFAGQVVHQLVPTAPALAKVLTWPAVFPTAST

Sequences:

>Translated_159_residues
MAPEELAALAELAKKQAHKVLAKVPLLGPVAWLMMQQATSRHTLLSELEWRVMPALVLDQAKLYLKDEAPVAFVSWARLS
DAVVQRYKTAPHQLTAADWVSGDQIWLIDVFTPFGGAQDVLKDLREKVFAGQVVHQLVPTAPALAKVLTWPAVFPTAST
>Mature_158_residues
APEELAALAELAKKQAHKVLAKVPLLGPVAWLMMQQATSRHTLLSELEWRVMPALVLDQAKLYLKDEAPVAFVSWARLSD
AVVQRYKTAPHQLTAADWVSGDQIWLIDVFTPFGGAQDVLKDLREKVFAGQVVHQLVPTAPALAKVLTWPAVFPTAST

Specific function: Involved in fatty acylation of the protoxin, thereby converting it to the active toxin [H]

COG id: COG2994

COG function: function code O; ACP:hemolysin acyltransferase (hemolysin-activating protein)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RTX toxin acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003996 [H]

Pfam domain/function: PF02794 HlyC [H]

EC number: NA

Molecular weight: Translated: 17503; Mature: 17371

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEELAALAELAKKQAHKVLAKVPLLGPVAWLMMQQATSRHTLLSELEWRVMPALVLDQ
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLYLKDEAPVAFVSWARLSDAVVQRYKTAPHQLTAADWVSGDQIWLIDVFTPFGGAQDV
HHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEECCCCCHHHH
LKDLREKVFAGQVVHQLVPTAPALAKVLTWPAVFPTAST
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
APEELAALAELAKKQAHKVLAKVPLLGPVAWLMMQQATSRHTLLSELEWRVMPALVLDQ
CHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLYLKDEAPVAFVSWARLSDAVVQRYKTAPHQLTAADWVSGDQIWLIDVFTPFGGAQDV
HHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEEEEECCCCCHHHH
LKDLREKVFAGQVVHQLVPTAPALAKVLTWPAVFPTAST
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2693022; 1937809 [H]