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The map label for this gene is tolC [H]

Identifier: 91786921

GI number: 91786921

Start: 1048324

End: 1049793

Strand: Direct

Name: tolC [H]

Synonym: Bpro_1022

Alternate gene names: 91786921

Gene position: 1048324-1049793 (Clockwise)

Preceding gene: 91786920

Following gene: 91786922

Centisome position: 20.16

GC content: 62.86

Gene sequence:

>1470_bases
GTGCTCTTTGCGGCAGCGCTTTTTTCAGTCAAGGTCAGCAAATCTTGCGCCGTAGGCCCTCATCCCAGCCTTCCCCCAGC
GGGGGAAGGAGCAAGAAAACGGGCCGAACGCGGCATTTGGTGGCCCCATCTGCGGCCAGGGCTGATACCTTTGGTCGGCG
TACCTTTGCTCCTGGGGTCATTTGGTGCTCTGGCTGACAACTTACTGGAGGTTTACCGCAAGGCGCAGGAGCGAGACCCG
ACCTACCGCGGAGCAGTCCATGCGCTGCAGGCGGCGCGTGAGCGGGTGCCCCAGGCGCGTGCCGGGTTAATGCCCGCCGT
GAATCTGGTTGGTGCGACCAGCCAGCAATCAGGGCAGGCTGCTTTCAGTGGGGCCCCTTATGTAGACCGCAACGTGCGCA
GCCGGAACTGGAATCTGCAACTGACACAGCCGCTGTGGCGCGCGGCCAGCTGGGTGGCCCTGAGCCAAGCCGAACAACAG
GAGTTGCTGGCCGAGGCACAGTTTCGGCAAACCGAACAAGAGTTGATACTGCGCACGGCGCAGGCCTATCTGGACGTGCT
GGTGGCGCAGGAGGCCGAACGCGTGGCGCGTCTGCAGATCGGCGCTGTCGAACAGCAATTGGGCTTGGCGCGCCGTAACT
TCGAGGTGGGCGTGGCGACGGTGACTGATGTCCACGAGGCCAAGTCCCGGCTCGACCTGTCACGCGCTCAAGCGGTCGCT
GCAGCCAGCGAGACGGAGAACAAGCGCGCTGAGCTTGCACGCATCCTGGGAGACTCGGGAGCGCGCCTGGCACGCTTGCA
CGACAACGGCCGCTTGCCGGGTTTACAGCCCGAGACTGTCCAACTCTGGGTGGAAAGTGCCCGCGAGCAGTCCCTGCAGG
TGCGCATCGCCTTGGCGGCCCTGGACGTGGCGGACCGGGAAATCGCCAAACACCGGGCGACTCATTTGCCCACTCTTGAC
TTGACGGCCGGCTATGGCACTAACTTCACCTCCGGCAGTATTACCTCGCCGGCGGATATTGCAACCCGCACACGCTCTGG
TCAAGTCGGGCTGAATCTGAACATCCCGCTTTACGCCGGCGGTGGGGTCCAGGCACGCGTGCGCGAAGCCACTGCCTTGA
AAGACAAAGCGGGGGAGGAGCTGGAGGCAGCTCGCCGGCACGCGATCACGCAGGCGCGCCAGGCATTCTCTGGCGTCGTC
AATGGTGCGGCGCAGGTCGAGGCGCTGGAATCTGCCATTTCCTCCAGCAAGAGTTCACTCGATGCCAACAAGGTCGGCTA
CCGCATCGGCACGCGTATCAATATTGATGTGCTGAACGCCGAGCAGCAGCTTCATGCCGCTCAGCGCGACTGGCACAAGG
CGCGTGTCGAGACCCTGATGCAGGGCCTGCGTTTGAAGGCCTCGAATGCAACGCTGGGCGAGACGGATTTGCAAGCCATC
AATGATCTATTGGAAACAGAAAAACCATGA

Upstream 100 bases:

>100_bases
CAGGAGGCCTTGCGTGAAAGATAAAGTACTTTCGCGCATGTTGTTGCGCCCAGCGCATTGGGCCAATCCTGCTTCTTCCC
TCTTTGGGGAAAGGAGGGGA

Downstream 100 bases:

>100_bases
CGAAGACATCGCCACCATCCACGCAGCTTCCTGCCGGCTCCGGGGAAGCTAACCCCATGGCTCCGGAGGAGCTGGCAGCG
CTGGCTGAGCTTGCCAAAAA

Product: Type I secretion outer membrane protein TolC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLFAAALFSVKVSKSCAVGPHPSLPPAGEGARKRAERGIWWPHLRPGLIPLVGVPLLLGSFGALADNLLEVYRKAQERDP
TYRGAVHALQAARERVPQARAGLMPAVNLVGATSQQSGQAAFSGAPYVDRNVRSRNWNLQLTQPLWRAASWVALSQAEQQ
ELLAEAQFRQTEQELILRTAQAYLDVLVAQEAERVARLQIGAVEQQLGLARRNFEVGVATVTDVHEAKSRLDLSRAQAVA
AASETENKRAELARILGDSGARLARLHDNGRLPGLQPETVQLWVESAREQSLQVRIALAALDVADREIAKHRATHLPTLD
LTAGYGTNFTSGSITSPADIATRTRSGQVGLNLNIPLYAGGGVQARVREATALKDKAGEELEAARRHAITQARQAFSGVV
NGAAQVEALESAISSSKSSLDANKVGYRIGTRINIDVLNAEQQLHAAQRDWHKARVETLMQGLRLKASNATLGETDLQAI
NDLLETEKP

Sequences:

>Translated_489_residues
MLFAAALFSVKVSKSCAVGPHPSLPPAGEGARKRAERGIWWPHLRPGLIPLVGVPLLLGSFGALADNLLEVYRKAQERDP
TYRGAVHALQAARERVPQARAGLMPAVNLVGATSQQSGQAAFSGAPYVDRNVRSRNWNLQLTQPLWRAASWVALSQAEQQ
ELLAEAQFRQTEQELILRTAQAYLDVLVAQEAERVARLQIGAVEQQLGLARRNFEVGVATVTDVHEAKSRLDLSRAQAVA
AASETENKRAELARILGDSGARLARLHDNGRLPGLQPETVQLWVESAREQSLQVRIALAALDVADREIAKHRATHLPTLD
LTAGYGTNFTSGSITSPADIATRTRSGQVGLNLNIPLYAGGGVQARVREATALKDKAGEELEAARRHAITQARQAFSGVV
NGAAQVEALESAISSSKSSLDANKVGYRIGTRINIDVLNAEQQLHAAQRDWHKARVETLMQGLRLKASNATLGETDLQAI
NDLLETEKP
>Mature_489_residues
MLFAAALFSVKVSKSCAVGPHPSLPPAGEGARKRAERGIWWPHLRPGLIPLVGVPLLLGSFGALADNLLEVYRKAQERDP
TYRGAVHALQAARERVPQARAGLMPAVNLVGATSQQSGQAAFSGAPYVDRNVRSRNWNLQLTQPLWRAASWVALSQAEQQ
ELLAEAQFRQTEQELILRTAQAYLDVLVAQEAERVARLQIGAVEQQLGLARRNFEVGVATVTDVHEAKSRLDLSRAQAVA
AASETENKRAELARILGDSGARLARLHDNGRLPGLQPETVQLWVESAREQSLQVRIALAALDVADREIAKHRATHLPTLD
LTAGYGTNFTSGSITSPADIATRTRSGQVGLNLNIPLYAGGGVQARVREATALKDKAGEELEAARRHAITQARQAFSGVV
NGAAQVEALESAISSSKSSLDANKVGYRIGTRINIDVLNAEQQLHAAQRDWHKARVETLMQGLRLKASNATLGETDLQAI
NDLLETEKP

Specific function: May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=432, Percent_Identity=32.4074074074074, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010130 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52872; Mature: 52872

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAAALFSVKVSKSCAVGPHPSLPPAGEGARKRAERGIWWPHLRPGLIPLVGVPLLLGS
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
FGALADNLLEVYRKAQERDPTYRGAVHALQAARERVPQARAGLMPAVNLVGATSQQSGQA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCCCC
AFSGAPYVDRNVRSRNWNLQLTQPLWRAASWVALSQAEQQELLAEAQFRQTEQELILRTA
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAYLDVLVAQEAERVARLQIGAVEQQLGLARRNFEVGVATVTDVHEAKSRLDLSRAQAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
AASETENKRAELARILGDSGARLARLHDNGRLPGLQPETVQLWVESAREQSLQVRIALAA
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHH
LDVADREIAKHRATHLPTLDLTAGYGTNFTSGSITSPADIATRTRSGQVGLNLNIPLYAG
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEEEC
GGVQARVREATALKDKAGEELEAARRHAITQARQAFSGVVNGAAQVEALESAISSSKSSL
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
DANKVGYRIGTRINIDVLNAEQQLHAAQRDWHKARVETLMQGLRLKASNATLGETDLQAI
CHHHCCEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHH
NDLLETEKP
HHHHHCCCC
>Mature Secondary Structure
MLFAAALFSVKVSKSCAVGPHPSLPPAGEGARKRAERGIWWPHLRPGLIPLVGVPLLLGS
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
FGALADNLLEVYRKAQERDPTYRGAVHALQAARERVPQARAGLMPAVNLVGATSQQSGQA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHCCCCCCCCCC
AFSGAPYVDRNVRSRNWNLQLTQPLWRAASWVALSQAEQQELLAEAQFRQTEQELILRTA
CCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAYLDVLVAQEAERVARLQIGAVEQQLGLARRNFEVGVATVTDVHEAKSRLDLSRAQAVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHH
AASETENKRAELARILGDSGARLARLHDNGRLPGLQPETVQLWVESAREQSLQVRIALAA
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHH
LDVADREIAKHRATHLPTLDLTAGYGTNFTSGSITSPADIATRTRSGQVGLNLNIPLYAG
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEEEC
GGVQARVREATALKDKAGEELEAARRHAITQARQAFSGVVNGAAQVEALESAISSSKSSL
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
DANKVGYRIGTRINIDVLNAEQQLHAAQRDWHKARVETLMQGLRLKASNATLGETDLQAI
CHHHCCEEECCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHH
NDLLETEKP
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]