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The map label for this gene is pabB [H]

Identifier: 91786806

GI number: 91786806

Start: 922051

End: 923835

Strand: Direct

Name: pabB [H]

Synonym: Bpro_0904

Alternate gene names: 91786806

Gene position: 922051-923835 (Clockwise)

Preceding gene: 91786805

Following gene: 91786810

Centisome position: 17.73

GC content: 69.92

Gene sequence:

>1785_bases
ATGGGAGCCTTGTCGGCACTCATCGACTTCTCCAACCCGGACCATCCCGACGGGCCACGTTTGCGCCAGGCCTTTGGCGT
GGCGCGCCAGGTGCTGGTGGCGCGCGAGCCGCAGCAGGTGCGCGCGGTGCTGGACGCAGTGCAGCAGGCTGCGCAGCAGG
GCGCCTGGTGCGTGGGTTACCTGCGCTACGAGGCCGCGCCCGCCTTCGATGCCGCGCTGGCCGTGCATCCGGCGGACGGG
CCCCTGGCATGGTTTGCGGTGTACGACGAGGCTTTGCCATGGCCGGGGGACGCGGCGGATGCGGCGGATGCAGCCGTCCA
GGTGCAGTGGCAGGAGACCTGTCCGCGCCCCGTTTTTGACGCGGCGCTGACAAGCATCCAGCACGCCATTGCCCAGGGTG
AGCTGTACCAGGTCAACATCACCGCACCGCTGCTGGGCACGTTGCGCGGCGAACCGGGGGGTGATGCGGCTCGCGCCCTG
TTTTCCGCCCTGCAGCGGGCCCAGCCCGGCGGCTATGCGGCCTTTCTGGACACCGGCGATGCGCAGGTGCTGTCGGTATC
CCCCGAGCTGTTTTTCGACTGGCATGCGGGCCGTATCCTGACGCGGCCCATGAAGGGCACGGCACGGCGCGGCGCCTCGC
CGCACGACGATGCAGCGCAGGCCGAGGCGCTGCGCACATCGGCCAAGGAGCGCGCCGAGAATGTGATGATCGTGGACTTG
CTGCGCAATGACCTGTCGCGCATCGCCCGGCCGTTCAGCGTGCGGGTGCCGCGCCTGTTCCACACCGAGGCGCTGCCCAC
GCTGTGGCAGATGACCTCGGACGTCGAGGCGCGCACGCGCGAAGGCTGTTCGCTGGCGGATGTCTTTGCCGCGCTGTTCC
CCTGCGGTTCGGTAACCGGCGCGCCCAAGGTGCGCGCGATGCAGATGATCCATGCGCTGGAACCGCAGGCGCGGGGTGTG
TACTGCGGCGCCGTTGGCGTGGTGCAGCCGGGCGAACACGGCGGCATCAGGGCCACGTTCAATGTACCCATCCGCACCGT
GACCCTGGGCGGGATGGCGCTGCGCTGCGGCATTGGCAGCGGTATCACCGCGGACGCCAGCGCCGACGGCGAGTGGCAGG
AGTGGCGCCACAAGCAGGCTTTTGTGCAGCGCGCCAGTGCGCCTTTTTCGCTGCTGGAAACGCTGGGACTGAAGGACGGG
TGTCTGCGTGATGCCGATGCGCATCTGGCCCGCATGGCGCTGGCGGCCCGGCATTTTGGCTACCCGTGGGATGTGCTTCA
GGTTGAGCGATCGCTGCAGGCGCTGGTGCAGGCCCATGCCCAGGGTGCGTGGCGGGTGCGCCTGCTGCTTGATGCGCAGG
GGCGAGCGCAGGCCGAGGCCCATGCGCTGGAAGCCGGGCCGGCGCGCGTGCGCCTGTGTCTGGCCGAACGTGCCATCGCC
GATGCGCACGATGAGTTCGTGCGTTTCAAGACCACCCGGCGGGCCCACTACGACGCATTCACCCCTGCCCAGCCGGGCGT
GTTCGACACCCTGCTGTGGAATACCGACGGCGAGATCACCGAATGCACGCGCGGCAACGTGGCGCTGCTGCTGGACGGCC
ACTGGGTCACGCCGCCGCTGCGGTGCGGATTGCTGGGGGGCGTAGCGCGCGCCAATGCCTTGCGCGAAGGCCGCGTGGCT
GAAGCCGTGGTCCGCGTGGCGGATCTGCCGCGGGTGCAGGCGCTGGCTTTTGTGAACAGCCTGCGCGGCTGGATCCCGGC
GGAGCTGGAGCCCCGCACCGCCTGA

Upstream 100 bases:

>100_bases
TGCGTGCCCGCCTGCCGATTGACCGCATGCTGGCGTTCACCGCTGCGCTGAAGGCCGGCCAGCCGGCGGGCGCGCTGGTG
CCGAACATCGGCGCGGCCTG

Downstream 100 bases:

>100_bases
TGCCCGCGTCGGTTCAGGCCGCTGGCGGCACGAGGATGGTCGGGGTCGCCGTGGCCGCCATGGCCGGGTAATCGCGGCTG
AAATGCAGGCCGCGGCTTTC

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MGALSALIDFSNPDHPDGPRLRQAFGVARQVLVAREPQQVRAVLDAVQQAAQQGAWCVGYLRYEAAPAFDAALAVHPADG
PLAWFAVYDEALPWPGDAADAADAAVQVQWQETCPRPVFDAALTSIQHAIAQGELYQVNITAPLLGTLRGEPGGDAARAL
FSALQRAQPGGYAAFLDTGDAQVLSVSPELFFDWHAGRILTRPMKGTARRGASPHDDAAQAEALRTSAKERAENVMIVDL
LRNDLSRIARPFSVRVPRLFHTEALPTLWQMTSDVEARTREGCSLADVFAALFPCGSVTGAPKVRAMQMIHALEPQARGV
YCGAVGVVQPGEHGGIRATFNVPIRTVTLGGMALRCGIGSGITADASADGEWQEWRHKQAFVQRASAPFSLLETLGLKDG
CLRDADAHLARMALAARHFGYPWDVLQVERSLQALVQAHAQGAWRVRLLLDAQGRAQAEAHALEAGPARVRLCLAERAIA
DAHDEFVRFKTTRRAHYDAFTPAQPGVFDTLLWNTDGEITECTRGNVALLLDGHWVTPPLRCGLLGGVARANALREGRVA
EAVVRVADLPRVQALAFVNSLRGWIPAELEPRTA

Sequences:

>Translated_594_residues
MGALSALIDFSNPDHPDGPRLRQAFGVARQVLVAREPQQVRAVLDAVQQAAQQGAWCVGYLRYEAAPAFDAALAVHPADG
PLAWFAVYDEALPWPGDAADAADAAVQVQWQETCPRPVFDAALTSIQHAIAQGELYQVNITAPLLGTLRGEPGGDAARAL
FSALQRAQPGGYAAFLDTGDAQVLSVSPELFFDWHAGRILTRPMKGTARRGASPHDDAAQAEALRTSAKERAENVMIVDL
LRNDLSRIARPFSVRVPRLFHTEALPTLWQMTSDVEARTREGCSLADVFAALFPCGSVTGAPKVRAMQMIHALEPQARGV
YCGAVGVVQPGEHGGIRATFNVPIRTVTLGGMALRCGIGSGITADASADGEWQEWRHKQAFVQRASAPFSLLETLGLKDG
CLRDADAHLARMALAARHFGYPWDVLQVERSLQALVQAHAQGAWRVRLLLDAQGRAQAEAHALEAGPARVRLCLAERAIA
DAHDEFVRFKTTRRAHYDAFTPAQPGVFDTLLWNTDGEITECTRGNVALLLDGHWVTPPLRCGLLGGVARANALREGRVA
EAVVRVADLPRVQALAFVNSLRGWIPAELEPRTA
>Mature_593_residues
GALSALIDFSNPDHPDGPRLRQAFGVARQVLVAREPQQVRAVLDAVQQAAQQGAWCVGYLRYEAAPAFDAALAVHPADGP
LAWFAVYDEALPWPGDAADAADAAVQVQWQETCPRPVFDAALTSIQHAIAQGELYQVNITAPLLGTLRGEPGGDAARALF
SALQRAQPGGYAAFLDTGDAQVLSVSPELFFDWHAGRILTRPMKGTARRGASPHDDAAQAEALRTSAKERAENVMIVDLL
RNDLSRIARPFSVRVPRLFHTEALPTLWQMTSDVEARTREGCSLADVFAALFPCGSVTGAPKVRAMQMIHALEPQARGVY
CGAVGVVQPGEHGGIRATFNVPIRTVTLGGMALRCGIGSGITADASADGEWQEWRHKQAFVQRASAPFSLLETLGLKDGC
LRDADAHLARMALAARHFGYPWDVLQVERSLQALVQAHAQGAWRVRLLLDAQGRAQAEAHALEAGPARVRLCLAERAIAD
AHDEFVRFKTTRRAHYDAFTPAQPGVFDTLLWNTDGEITECTRGNVALLLDGHWVTPPLRCGLLGGVARANALREGRVAE
AVVRVADLPRVQALAFVNSLRGWIPAELEPRTA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=272, Percent_Identity=38.9705882352941, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1787518, Length=277, Percent_Identity=30.6859205776173, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1786809, Length=220, Percent_Identity=29.0909090909091, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=268, Percent_Identity=32.089552238806, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324361, Length=322, Percent_Identity=27.639751552795, Blast_Score=103, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 64108; Mature: 63977

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALSALIDFSNPDHPDGPRLRQAFGVARQVLVAREPQQVRAVLDAVQQAAQQGAWCVGY
CCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEE
LRYEAAPAFDAALAVHPADGPLAWFAVYDEALPWPGDAADAADAAVQVQWQETCPRPVFD
EEECCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEHHCCCCHHHH
AALTSIQHAIAQGELYQVNITAPLLGTLRGEPGGDAARALFSALQRAQPGGYAAFLDTGD
HHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCC
AQVLSVSPELFFDWHAGRILTRPMKGTARRGASPHDDAAQAEALRTSAKERAENVMIVDL
CEEEEECCCEEEEECCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEHHHH
LRNDLSRIARPFSVRVPRLFHTEALPTLWQMTSDVEARTREGCSLADVFAALFPCGSVTG
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
APKVRAMQMIHALEPQARGVYCGAVGVVQPGEHGGIRATFNVPIRTVTLGGMALRCGIGS
CCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEEEEEECCEEEEEECCEEEEECCCC
GITADASADGEWQEWRHKQAFVQRASAPFSLLETLGLKDGCLRDADAHLARMALAARHFG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
YPWDVLQVERSLQALVQAHAQGAWRVRLLLDAQGRAQAEAHALEAGPARVRLCLAERAIA
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHH
DAHDEFVRFKTTRRAHYDAFTPAQPGVFDTLLWNTDGEITECTRGNVALLLDGHWVTPPL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEEECCCCCCCHH
RCGLLGGVARANALREGRVAEAVVRVADLPRVQALAFVNSLRGWIPAELEPRTA
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GALSALIDFSNPDHPDGPRLRQAFGVARQVLVAREPQQVRAVLDAVQQAAQQGAWCVGY
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEE
LRYEAAPAFDAALAVHPADGPLAWFAVYDEALPWPGDAADAADAAVQVQWQETCPRPVFD
EEECCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEEHHCCCCHHHH
AALTSIQHAIAQGELYQVNITAPLLGTLRGEPGGDAARALFSALQRAQPGGYAAFLDTGD
HHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCC
AQVLSVSPELFFDWHAGRILTRPMKGTARRGASPHDDAAQAEALRTSAKERAENVMIVDL
CEEEEECCCEEEEECCCEEEECCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEHHHH
LRNDLSRIARPFSVRVPRLFHTEALPTLWQMTSDVEARTREGCSLADVFAALFPCGSVTG
HHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
APKVRAMQMIHALEPQARGVYCGAVGVVQPGEHGGIRATFNVPIRTVTLGGMALRCGIGS
CCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCEEEEEECCEEEEEECCEEEEECCCC
GITADASADGEWQEWRHKQAFVQRASAPFSLLETLGLKDGCLRDADAHLARMALAARHFG
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
YPWDVLQVERSLQALVQAHAQGAWRVRLLLDAQGRAQAEAHALEAGPARVRLCLAERAIA
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHH
DAHDEFVRFKTTRRAHYDAFTPAQPGVFDTLLWNTDGEITECTRGNVALLLDGHWVTPPL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCEEEEECCCCCCCHH
RCGLLGGVARANALREGRVAEAVVRVADLPRVQALAFVNSLRGWIPAELEPRTA
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]