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The map label for this gene is gpsA

Identifier: 91786792

GI number: 91786792

Start: 910024

End: 911085

Strand: Direct

Name: gpsA

Synonym: Bpro_0890

Alternate gene names: 91786792

Gene position: 910024-911085 (Clockwise)

Preceding gene: 161936271

Following gene: 91786794

Centisome position: 17.5

GC content: 67.61

Gene sequence:

>1062_bases
ATGAAAATAGTCGTCATTGGTGCCGGCGCATGGGGTACGGCACTGGCCGTCAATACGGCAGGTGCTGTGGAGGCGGCGGG
CTCCGACGCGCCCCGGCATCAGGTCACGCTGTGGGCGCGCGACGCGGCGCTGGTCAAGGCCATGCAGGCCGAGCGCGCCA
ACACCCGCTACCTGCCCGGCGTGGCCTTGCCCGGCAACCTGCTGCTGCAAGGCGGCGGGGAGACCTCGTTGGCCGAGGCC
GTCAGCGGACAGGACCTGATCATCCTGGCCACGCCGGTTTCCGCCGCGCGCGGCTTGTTGCAAAGCCTGCAGCAGGCCAG
CGTTCCGGTCGTCTGGCTGAGCAAGGGTTTTGAAGCGCCGGTTGCCGCGGTACCCCACTCAGCCCCCTCTTTAGCGTCAT
TTGGCCTGATGGTCCATGAAATACGGGCGCAGGTTGCTACTGATTTGAGAGCGGGCATACTCAGCGGACCGAGTTTCGCG
CTCGAAGTGGCACGCGGCCAGCCGACCGCCCTGGTCGCCGCCAGCGAGCATGCCGAGGTGCGCGATGCACTGGTTGCGGC
ATTCCACGGCACCTCACTGCGCATTTACGCCAGCGACGATATCGTGGGTGTTGAGGTCGGCGGCGCTGTCAAGAATGTGC
TGGCCATCGCTACGGGCCTGTGCGACGGCCTGCAATTGGGGCTGAACGCCCGCGCCGCCCTGATCACGCGCGGGCTCGCC
GAAATGACGCGGCTGGGCGTGACCCTGGGCGCCCGTGCCGAAACCTTTACCGGCCTGTCGGGACTGGGCGACCTGGTGCT
GACGGCCACCGGTGATCTCAGCCGCAACCGCAAGGTGGGGCTGCAACTGGCGCAGGGCAAAACCCTGGCCGAAGCGGTCA
AGTCACTGGGGCATGTGGCCGAGGGCGTTTATTGCGCCCGCACGGTGGTGCAGCGTGCCGCCGGCCTGGGGGTCGACATG
CCGATTGCGCAAAGCGTGGTGGCACTGCTGGATGGCAAGCTCCGGCCGGCTGAAGCCGTCGCTGCCCTGATGGGGCGTGG
GCCGACGACTGAACTGGCCTGA

Upstream 100 bases:

>100_bases
TGTACGAGCAGCAGCAGGCCGAGGCCGCCACGCCCCAAATCATCGTTTAAGGGGCGGCTGAACCGCTGCCCGCCTTTTTC
GCTCATCCGCTCATCTGGAC

Downstream 100 bases:

>100_bases
GTATGGCTGCTTGTTTTGCTATTGAATAAATAGCGTAAAACGACCGATCTGATGGGATTCAAGCCTTCAGGCTGGTTTAC
TTGCGCAACACCAGGGTCAC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKIVVIGAGAWGTALAVNTAGAVEAAGSDAPRHQVTLWARDAALVKAMQAERANTRYLPGVALPGNLLLQGGGETSLAEA
VSGQDLIILATPVSAARGLLQSLQQASVPVVWLSKGFEAPVAAVPHSAPSLASFGLMVHEIRAQVATDLRAGILSGPSFA
LEVARGQPTALVAASEHAEVRDALVAAFHGTSLRIYASDDIVGVEVGGAVKNVLAIATGLCDGLQLGLNARAALITRGLA
EMTRLGVTLGARAETFTGLSGLGDLVLTATGDLSRNRKVGLQLAQGKTLAEAVKSLGHVAEGVYCARTVVQRAAGLGVDM
PIAQSVVALLDGKLRPAEAVAALMGRGPTTELA

Sequences:

>Translated_353_residues
MKIVVIGAGAWGTALAVNTAGAVEAAGSDAPRHQVTLWARDAALVKAMQAERANTRYLPGVALPGNLLLQGGGETSLAEA
VSGQDLIILATPVSAARGLLQSLQQASVPVVWLSKGFEAPVAAVPHSAPSLASFGLMVHEIRAQVATDLRAGILSGPSFA
LEVARGQPTALVAASEHAEVRDALVAAFHGTSLRIYASDDIVGVEVGGAVKNVLAIATGLCDGLQLGLNARAALITRGLA
EMTRLGVTLGARAETFTGLSGLGDLVLTATGDLSRNRKVGLQLAQGKTLAEAVKSLGHVAEGVYCARTVVQRAAGLGVDM
PIAQSVVALLDGKLRPAEAVAALMGRGPTTELA
>Mature_353_residues
MKIVVIGAGAWGTALAVNTAGAVEAAGSDAPRHQVTLWARDAALVKAMQAERANTRYLPGVALPGNLLLQGGGETSLAEA
VSGQDLIILATPVSAARGLLQSLQQASVPVVWLSKGFEAPVAAVPHSAPSLASFGLMVHEIRAQVATDLRAGILSGPSFA
LEVARGQPTALVAASEHAEVRDALVAAFHGTSLRIYASDDIVGVEVGGAVKNVLAIATGLCDGLQLGLNARAALITRGLA
EMTRLGVTLGARAETFTGLSGLGDLVLTATGDLSRNRKVGLQLAQGKTLAEAVKSLGHVAEGVYCARTVVQRAAGLGVDM
PIAQSVVALLDGKLRPAEAVAALMGRGPTTELA

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=310, Percent_Identity=28.7096774193548, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI33695088, Length=346, Percent_Identity=27.4566473988439, Blast_Score=93, Evalue=4e-19,
Organism=Escherichia coli, GI1790037, Length=354, Percent_Identity=37.8531073446328, Blast_Score=218, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=29.8882681564246, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=29.8882681564246, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32564399, Length=358, Percent_Identity=29.8882681564246, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193210134, Length=350, Percent_Identity=27.7142857142857, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17507425, Length=298, Percent_Identity=25.8389261744966, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324513, Length=363, Percent_Identity=28.3746556473829, Blast_Score=115, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6320181, Length=357, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281362270, Length=279, Percent_Identity=27.2401433691756, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI45551945, Length=279, Percent_Identity=27.2401433691756, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17136200, Length=358, Percent_Identity=26.8156424581006, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17136204, Length=358, Percent_Identity=26.8156424581006, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17136202, Length=358, Percent_Identity=26.8156424581006, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI22026922, Length=343, Percent_Identity=25.3644314868805, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24648969, Length=238, Percent_Identity=26.890756302521, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_POLSJ (Q12F46)

Other databases:

- EMBL:   CP000316
- RefSeq:   YP_547744.1
- ProteinModelPortal:   Q12F46
- SMR:   Q12F46
- STRING:   Q12F46
- GeneID:   4011198
- GenomeReviews:   CP000316_GR
- KEGG:   pol:Bpro_0890
- NMPDR:   fig|296591.1.peg.3043
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- PhylomeDB:   Q12F46
- ProtClustDB:   PRK00094
- BioCyc:   PSP296591:BPRO_0890-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 35796; Mature: 35796

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 211-211 BINDING 115-115 BINDING 115-115 BINDING 160-160 BINDING 275-275 BINDING 301-301

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVVIGAGAWGTALAVNTAGAVEAAGSDAPRHQVTLWARDAALVKAMQAERANTRYLPG
CEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCC
VALPGNLLLQGGGETSLAEAVSGQDLIILATPVSAARGLLQSLQQASVPVVWLSKGFEAP
CCCCCCEEEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCC
VAAVPHSAPSLASFGLMVHEIRAQVATDLRAGILSGPSFALEVARGQPTALVAASEHAEV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHH
RDALVAAFHGTSLRIYASDDIVGVEVGGAVKNVLAIATGLCDGLQLGLNARAALITRGLA
HHHHHHHCCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EMTRLGVTLGARAETFTGLSGLGDLVLTATGDLSRNRKVGLQLAQGKTLAEAVKSLGHVA
HHHHHCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCEECEEEECCCHHHHHHHHHHHHH
EGVYCARTVVQRAAGLGVDMPIAQSVVALLDGKLRPAEAVAALMGRGPTTELA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKIVVIGAGAWGTALAVNTAGAVEAAGSDAPRHQVTLWARDAALVKAMQAERANTRYLPG
CEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCC
VALPGNLLLQGGGETSLAEAVSGQDLIILATPVSAARGLLQSLQQASVPVVWLSKGFEAP
CCCCCCEEEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCCC
VAAVPHSAPSLASFGLMVHEIRAQVATDLRAGILSGPSFALEVARGQPTALVAASEHAEV
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHH
RDALVAAFHGTSLRIYASDDIVGVEVGGAVKNVLAIATGLCDGLQLGLNARAALITRGLA
HHHHHHHCCCCEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EMTRLGVTLGARAETFTGLSGLGDLVLTATGDLSRNRKVGLQLAQGKTLAEAVKSLGHVA
HHHHHCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCEECEEEECCCHHHHHHHHHHHHH
EGVYCARTVVQRAAGLGVDMPIAQSVVALLDGKLRPAEAVAALMGRGPTTELA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA