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The map label for this gene is ttdA [H]

Identifier: 91212489

GI number: 91212489

Start: 3434273

End: 3435184

Strand: Direct

Name: ttdA [H]

Synonym: UTI89_C3497

Alternate gene names: 91212489

Gene position: 3434273-3435184 (Clockwise)

Preceding gene: 91212487

Following gene: 91212490

Centisome position: 67.79

GC content: 53.29

Gene sequence:

>912_bases
ATGATGAGCGAAAGTAATAAGCAACAGGCAGTGAATAAGTTGACGGAGATTGTCGCTAACTTTACCGCCATGATTTCTAC
CCGAATGCCTGATGACGTGGTGGATAAACTAAAACAGCTAAAGGATGCCGAAACATCGTCGATGGGAAAAATCATCTACC
ACACGATGTTCGATAACATGCAAAAAGCGATCGACCTGAATCGTCCTGCCTGTCAGGACACCGGCGAAATCATGTTTTTT
GTTAAGGTCGGTTCCCGTTTCCCACTGCTTGGCGAGCTGCAAAGCATACTCAAACAAGCCGTGGAAGAGGCAACCGTCAA
AGCGCCACTGCGTCACAATGCGGTAGAAATTTTTGACGAAGTAAACACCGGCAAAAATACCGGCAGTGGCGTACCGTGGG
TCACCTGGGATATCGTCCCCGACGGTGACGATGCGGAAATCGAAGTTTACATGGCAGGCGGCGGCTGCACGCTACCTGGC
CGATCGAAAGTGTTAATGCCGTCAGAAGGCTACGAAGGCGTAGTGAAATTCGTCTTCGAAAATATCTCCACCCTCGCCGT
AAACGCCTGTCCGCCGGTACTTGTGGGCGTTGGCATCGCTACCTCGGTGGAAACCGCCGCAGTGCTCTCGCGTAAAGCCA
TTTTGCGCCCGATTGGCAGCCGCCATCCCAATCCAAAAGCGGCAGAGCTGGAGCTACGCCTGGAAGAAGGACTCAACCGT
CTGGGGATTGGTCCACAAGGGCTGACTGGCAACAGTTCAGTGATGGGCGTGCATATCGAATCTGCCGCTCGCCATCCGTC
AACCATCGGCGTTGCTGTTTCTACCGGCTGCTGGGCGCATCGTCGCGGCACACTGCGAGTTCATGCCGATCTCACCTTTG
AAAATCTGTCTCATACCCGGAGCGCGTTATGA

Upstream 100 bases:

>100_bases
TTAATTACATATTCACGGTGGCAAAAAATATAAAACCACATTTTTAGTGGTAGTTTGTGGCGGTGAATTTTTCCAGACAA
ATACATAAACTGGAGTTGCC

Downstream 100 bases:

>100_bases
AAAAGATCCTGACAACCCCGATCAAAGCTGAAGATCTGCAAGATATTCGCGTCGGCGATGTGATCTACCTGACCGGTACG
CTGGTGACCTGCCGTGACGT

Product: tartrate dehydratase subunit alpha

Products: NA

Alternate protein names: L-TTD alpha [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLRVHADLTFENLSHTRSAL

Sequences:

>Translated_303_residues
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLRVHADLTFENLSHTRSAL
>Mature_303_residues
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLRVHADLTFENLSHTRSAL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=303, Percent_Identity=99.009900990099, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1790564, Length=276, Percent_Identity=26.8115942028986, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787897, Length=277, Percent_Identity=26.3537906137184, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.32 [H]

Molecular weight: Translated: 32706; Mature: 32706

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDE
HHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHH
VNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPGRSKVLMPSEGYEGVVKFVFE
HCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHH
NISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
HHHHEEECCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHCHHH
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLRVHADLTFENLSHTR
HCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCHHHHHHHH
SAL
HCC
>Mature Secondary Structure
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNM
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVEEATVKAPLRHNAVEIFDE
HHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHH
VNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPGRSKVLMPSEGYEGVVKFVFE
HCCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCEEECCCCCHHHHHHHHHH
NISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
HHHHEEECCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEHHHCHHH
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLRVHADLTFENLSHTR
HCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCHHHHHHHH
SAL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]