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The map label for this gene is yggW [H]

Identifier: 91212337

GI number: 91212337

Start: 3274909

End: 3276045

Strand: Direct

Name: yggW [H]

Synonym: UTI89_C3344

Alternate gene names: 91212337

Gene position: 3274909-3276045 (Clockwise)

Preceding gene: 91212336

Following gene: 91212344

Centisome position: 64.65

GC content: 52.42

Gene sequence:

>1137_bases
ATGGTTAAATTACCGCCGCTGAGTCTCTACATTCACATCCCGTGGTGCGTGCAGAAATGCCCGTACTGCGATTTCAACTC
TCACGCGTTGAAAGGAGAAGTGCCGCACGACGATTATGTTCAGCATCTGCTTAACGATCTGGACAACGATGTGGCTTACG
CTCAGGGCCGTGAAGTGCAGACAATCTTTATTGGCGGTGGTACGCCGAGCCTGCTTTCCGGCCCGGCGATGCAAACGCTG
CTGGACGGCGTGCGTGCGCGTTTGCCGCTGACAGCGGATGCAGAAATTACGATGGAAGCGAACCCTGGTACGGTTGAAGC
CGATCGCTTTGTCGATTATCAGCGTGCTGGTGTGAACCGCATCTCTATTGGTGTGCAGAGTTTTAGCGAAGAAAAGCTGA
AACGACTTGGGCGCATTCATGGCCCGCAAGAAGCGAAACGAGCTGCGAAGCTGGCGAGCGGTTTAGGGTTACGTAGCTTT
AACCTTGATTTGATGCATGGGCTGCCGGATCAATCACTGGAAGAGGCGCTAGGCGATCTGCGCCAGGCTATTGAACTGAA
TCCGCCGCATCTTTCCTGGTATCAACTGACCATCGAACCTAATACGCTGTTTGGCTCTCGCCCACCGGTGCTGCCGGACG
ACGATGCGTTGTGGGATATATTCGAACAGGGGCATCAGTTATTAACCGCAGCGGGTTATCAGCAATATGAAACTTCCGCT
TACTCCAAACCCGGTTATCAGTGCCAGCACAATCTCAACTACTGGCGCTTTGGTGACTACATTGGTATTGGCTGCGGCGC
GCACGGCAAAGTGACCTTCCCGGATGGGCGCATTCTGCGTACCACCAAAACGCGTCATCCGCGTGGTTTTATGCAGGGAA
GATATCTGGAAAGCCAGCGTGATGTCGAAGCTGCAGATAAACCGTTTGAGTTCTTTATGAATCGCTTCCGTCTGCTGGAA
GCCGCGCCGCGCGTGGAGTTTAGCCAGTATACTGGCCTTTCTGAAGAAGTTATTCGCCCACAGTTAGAAGAGGCTATCGC
TCAGGGTTATCTCACAGAATGTGCAGATTACTGGCAGATAACGGAACATGGGAAGTTGTTTTTAAATTCGTTGCTGGAGC
TTTTTCTGGCGGAGTAA

Upstream 100 bases:

>100_bases
CCTTCCGAAGGGAAAACCGCTGCCGAACTGACCCGCGAAGAAAAGAGCGCCATTTCCCACCGTGGTCAGGCGTTGAAACT
GCTGCTGGACGCTTTACGTA

Downstream 100 bases:

>100_bases
ATTTGTATTGCCGGATGCGGCGTGCGTGTACGCAGCATCCGGCAACAACTCATGCGTCATCGCAAAAATTACTTAATCAC
CCCATTGCGCCGCAGTTGTT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTL
LDGVRARLPLTADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YSKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLE
AAPRVEFSQYTGLSEEVIRPQLEEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE

Sequences:

>Translated_378_residues
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTL
LDGVRARLPLTADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YSKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLE
AAPRVEFSQYTGLSEEVIRPQLEEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE
>Mature_378_residues
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQTIFIGGGTPSLLSGPAMQTL
LDGVRARLPLTADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YSKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLE
AAPRVEFSQYTGLSEEVIRPQLEEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=284, Percent_Identity=34.8591549295775, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=97.6190476190476, Blast_Score=769, Evalue=0.0,
Organism=Escherichia coli, GI87082341, Length=244, Percent_Identity=32.3770491803279, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42644; Mature: 42644

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCEEE
TIFIGGGTPSLLSGPAMQTLLDGVRARLPLTADAEITMEANPGTVEADRFVDYQRAGVNR
EEEECCCCCHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
ISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSFNLDLMHGLPDQSLEEALGDL
EEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHC
YSKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQR
CCCCCCCEECCCCEEEECCEEEECCCCCCEEECCCCCEEEECCCCCCCCHHCCCCCCCCC
DVEAADKPFEFFMNRFRLLEAAPRVEFSQYTGLSEEVIRPQLEEAIAQGYLTECADYWQI
CCHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEHGKLFLNSLLELFLAE
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVQ
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCEEE
TIFIGGGTPSLLSGPAMQTLLDGVRARLPLTADAEITMEANPGTVEADRFVDYQRAGVNR
EEEECCCCCHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCE
ISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSFNLDLMHGLPDQSLEEALGDL
EEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHC
YSKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQR
CCCCCCCEECCCCEEEECCEEEECCCCCCEEECCCCCEEEECCCCCCCCHHCCCCCCCCC
DVEAADKPFEFFMNRFRLLEAAPRVEFSQYTGLSEEVIRPQLEEAIAQGYLTECADYWQI
CCHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEHGKLFLNSLLELFLAE
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]