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The map label for this gene is flmA

Identifier: 91206343

GI number: 91206343

Start: 74286

End: 74444

Strand: Direct

Name: flmA

Synonym: UTI89_P098

Alternate gene names: 91206343

Gene position: 74286-74444 (Clockwise)

Preceding gene: 91206342

Following gene: 91206345

Centisome position: 65.03

GC content: 47.8

Gene sequence:

>159_bases
ATGAAACTACCACGCAGCTCTCTTGTCTGGTGTGTGTTGATCGTGTGTCTCACACTGTTGATATTCACTTATCTGACACG
AAAATCGCTGTGCGAGATTCGTTACAGAGACGGATACAGGGAGGTGGCGGCTTTCATGGCTTACGAATCCGGTAAGTAG

Upstream 100 bases:

>100_bases
AAGCCCCGTAGTTAATTTTTCATTAACCCACGAGGCCCCTGCATGCTTAGACAACATCAGGATAGCCTCTTACCGCGCTT
TGCGCAAGGAGAAGAAGGCC

Downstream 100 bases:

>100_bases
CAACCTGGAGGCGGGCGCAGGCCCGCCTTTTCAGGGCTGATGCTGGTCTGACTGCACTGAAGCGCCTTTATAAAGGGGCT
GCTGGTTCGCCGGTGGTCCC

Product: small toxic polypeptide

Products: NA

Alternate protein names: F leading maintenance protein

Number of amino acids: Translated: 52; Mature: 52

Protein sequence:

>52_residues
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK

Sequences:

>Translated_52_residues
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
>Mature_52_residues
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK

Specific function: FlmA extends the life of unstable plasmids

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FLMA_ECO57 (P62671)

Other databases:

- EMBL:   AF074613
- EMBL:   AB011549
- PIR:   JS0432
- RefSeq:   NP_052660.1
- RefSeq:   YP_325650.1
- EnsemblBacteria:   EBESCT00000029430
- EnsemblBacteria:   EBESCT00000060711
- GeneID:   1789673
- GeneID:   3683664
- GenomeReviews:   AB011549_GR
- GenomeReviews:   AF074613_GR
- KEGG:   ece:L7090
- GeneTree:   EBGT00050000009512
- HOGENOM:   HBG473224
- OMA:   RDGHREV
- ProtClustDB:   PRK09738
- InterPro:   IPR000021
- InterPro:   IPR018084
- PRINTS:   PR00281
- ProDom:   PD005979

Pfam domain/function: PF01848 HOK_GEF

EC number: NA

Molecular weight: Translated: 6108; Mature: 6108

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x110fb728)-;

Cys/Met content:

5.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
>Mature Secondary Structure
MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9722640; 9628576