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The map label for this gene is ybbO [H]

Identifier: 89256603

GI number: 89256603

Start: 1233628

End: 1234452

Strand: Direct

Name: ybbO [H]

Synonym: FTL_1294

Alternate gene names: 89256603

Gene position: 1233628-1234452 (Clockwise)

Preceding gene: 89256602

Following gene: 89256607

Centisome position: 65.06

GC content: 32.48

Gene sequence:

>825_bases
ATGGTAAACAATAGTAAAACAATCCTTATAACTGGTTGTTCTCATGGTGGTATAGGTTACGCTACTGCTGTACATCTTAA
AAATTTAGGTCACAGAGTTTTTGCTTCAGCAAGACAGCAAAAAGATGTAGAAGCACTTAGTCAAGAAGGCTTCGAAACTT
ATCTTATAGATGTAACTAACTATGAGTATATCGATAATGCTTTAGCTGATATCTTAAATAAAACTGGTGGCTCTCTAGAT
GTAATATTTAATAATGCTGGATATGGTCAGGCTGGTGCTTTAGAAGATATTGATACTAAGTTTCTCAAACAACAATTTGA
AACAAATGTATTTGGATTACACAACTTAACATACAAAGCTCTAAAAATAATGCGAAAACAAGGTTATGGTAAAATCATCC
AACATAGTTCAGTACTAGGGCTAGTTGCAATGAAGTATCGTGGTGCATACAACGCAAGTAAATATGCTATAGAAGGCCTC
ACAGATACGATGCGTCTAGAACTCAGGGACTCTAATATTTTCATAACTAGTTTAAACACAGGACCTATTACTAGTAAATT
TAGAGAAAACTCTATCAAAACAATTACTAATGTTAATTATGACTCCTCAGTGCATAAACAACAGTATGAAAAAATACTTG
CATGCCAACATAAAAAAGTCCCTTTTAATGAACCTGCTATTTCGGTTGCAAAAGTTGTTGAAAAGATAATAAATTGCGAT
AAGCCAAAACCAAGATATTATATTACCAAAGCAACTTGGATTATGGCATCGTTAAAAAGGATACTACCAACAAATATTCT
AGATAATTTCCTTAATAGATATTAG

Upstream 100 bases:

>100_bases
GATTCAAAAATATTTTAGAGAATCTTAAATAAGATAAATTTACATAGTAAGTGTTTTAACCTAAACTAATCAATATAAAA
ACACACTCTAATTTAATATT

Downstream 100 bases:

>100_bases
TGGAACTATATTTCTGAATAATTATCGCTTGAATTTATATAACAACCAACCGATAAATATAAAAATTACAGGTCCAAGGA
TTAATTCAAATTCATATATG

Product: Short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MVNNSKTILITGCSHGGIGYATAVHLKNLGHRVFASARQQKDVEALSQEGFETYLIDVTNYEYIDNALADILNKTGGSLD
VIFNNAGYGQAGALEDIDTKFLKQQFETNVFGLHNLTYKALKIMRKQGYGKIIQHSSVLGLVAMKYRGAYNASKYAIEGL
TDTMRLELRDSNIFITSLNTGPITSKFRENSIKTITNVNYDSSVHKQQYEKILACQHKKVPFNEPAISVAKVVEKIINCD
KPKPRYYITKATWIMASLKRILPTNILDNFLNRY

Sequences:

>Translated_274_residues
MVNNSKTILITGCSHGGIGYATAVHLKNLGHRVFASARQQKDVEALSQEGFETYLIDVTNYEYIDNALADILNKTGGSLD
VIFNNAGYGQAGALEDIDTKFLKQQFETNVFGLHNLTYKALKIMRKQGYGKIIQHSSVLGLVAMKYRGAYNASKYAIEGL
TDTMRLELRDSNIFITSLNTGPITSKFRENSIKTITNVNYDSSVHKQQYEKILACQHKKVPFNEPAISVAKVVEKIINCD
KPKPRYYITKATWIMASLKRILPTNILDNFLNRY
>Mature_274_residues
MVNNSKTILITGCSHGGIGYATAVHLKNLGHRVFASARQQKDVEALSQEGFETYLIDVTNYEYIDNALADILNKTGGSLD
VIFNNAGYGQAGALEDIDTKFLKQQFETNVFGLHNLTYKALKIMRKQGYGKIIQHSSVLGLVAMKYRGAYNASKYAIEGL
TDTMRLELRDSNIFITSLNTGPITSKFRENSIKTITNVNYDSSVHKQQYEKILACQHKKVPFNEPAISVAKVVEKIINCD
KPKPRYYITKATWIMASLKRILPTNILDNFLNRY

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=213, Percent_Identity=30.9859154929577, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI223718074, Length=259, Percent_Identity=28.5714285714286, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI7706318, Length=215, Percent_Identity=29.7674418604651, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=32.1243523316062, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=30.4568527918782, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI40548397, Length=183, Percent_Identity=32.2404371584699, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI214010158, Length=183, Percent_Identity=32.2404371584699, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI214010156, Length=183, Percent_Identity=32.2404371584699, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI22758144, Length=183, Percent_Identity=32.2404371584699, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI150247226, Length=287, Percent_Identity=28.9198606271777, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI44680136, Length=227, Percent_Identity=25.9911894273128, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI44680133, Length=227, Percent_Identity=25.9911894273128, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI17738292, Length=227, Percent_Identity=25.9911894273128, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI19743808, Length=295, Percent_Identity=27.4576271186441, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786701, Length=276, Percent_Identity=38.0434782608696, Blast_Score=185, Evalue=2e-48,
Organism=Escherichia coli, GI1786812, Length=172, Percent_Identity=30.2325581395349, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI87082160, Length=180, Percent_Identity=26.6666666666667, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71997402, Length=189, Percent_Identity=32.2751322751323, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17570069, Length=189, Percent_Identity=32.2751322751323, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507613, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=278, Percent_Identity=29.136690647482, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=222, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24641232, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24651139, Length=197, Percent_Identity=29.4416243654822, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI116007238, Length=177, Percent_Identity=29.9435028248588, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355319, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364892, Length=231, Percent_Identity=28.1385281385281, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571387, Length=204, Percent_Identity=29.9019607843137, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648944, Length=194, Percent_Identity=32.4742268041237, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356301, Length=180, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357041, Length=222, Percent_Identity=28.8288288288288, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30801; Mature: 30801

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNNSKTILITGCSHGGIGYATAVHLKNLGHRVFASARQQKDVEALSQEGFETYLIDVTN
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
YEYIDNALADILNKTGGSLDVIFNNAGYGQAGALEDIDTKFLKQQFETNVFGLHNLTYKA
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHH
LKIMRKQGYGKIIQHSSVLGLVAMKYRGAYNASKYAIEGLTDTMRLELRDSNIFITSLNT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEEEECCEEEEEECCC
GPITSKFRENSIKTITNVNYDSSVHKQQYEKILACQHKKVPFNEPAISVAKVVEKIINCD
CCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
KPKPRYYITKATWIMASLKRILPTNILDNFLNRY
CCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MVNNSKTILITGCSHGGIGYATAVHLKNLGHRVFASARQQKDVEALSQEGFETYLIDVTN
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
YEYIDNALADILNKTGGSLDVIFNNAGYGQAGALEDIDTKFLKQQFETNVFGLHNLTYKA
HHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHH
LKIMRKQGYGKIIQHSSVLGLVAMKYRGAYNASKYAIEGLTDTMRLELRDSNIFITSLNT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEEEECCEEEEEECCC
GPITSKFRENSIKTITNVNYDSSVHKQQYEKILACQHKKVPFNEPAISVAKVVEKIINCD
CCCCHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
KPKPRYYITKATWIMASLKRILPTNILDNFLNRY
CCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]