| Definition | Francisella tularensis subsp. holarctica LVS chromosome, complete genome. |
|---|---|
| Accession | NC_007880 |
| Length | 1,895,994 |
Click here to switch to the map view.
The map label for this gene is rlmL [H]
Identifier: 89256596
GI number: 89256596
Start: 1226661
End: 1228814
Strand: Reverse
Name: rlmL [H]
Synonym: FTL_1287
Alternate gene names: 89256596
Gene position: 1228814-1226661 (Counterclockwise)
Preceding gene: 89256597
Following gene: 89256595
Centisome position: 64.81
GC content: 30.92
Gene sequence:
>2154_bases ATGCAAAAATTTACTTTTTTCGTTAGCTGTGCTAAAGGTATTGAGCTCCTACTCAAAGATGAGCTAGAAAGATTAGGTAT ATCTTCTCAAGAAAAACTCGCTGGTGTAGAGTTTGAAGGCTCTATTAAAGATGCATATAAGGTATGTATATATTCTTATT TAGCTAGTCAAGTTATGCTAAAAGTAGCTACTGATAAAGTCATAAATCAACAAGATTTATATGAATTTATATCATCTATA AACTGGATGGATTATTTTGCTGTTGATAAAACTTTTAAAATTATAATTTCCGGTAAACATTATGATTTTAATAATACAAT GTTTGTTTCCCAAAAGACCAAAGATGCTATTGTTGACCAGTTTAGAAATGTTATAAATCAACGCCCGAATATAGATACAG AAAATCCTGATAATGTCATTAAACTTCACTTACACAAACAATTTGTAAATGTATTCTTGTGCTTAAATATTGATAGCTTA CACAAACGCAGTTATCGTCAGTTTCAGGGACAAGCGCCGCTAAAAGAATCATTAGCAGCTGCAATACTTATCAAAGCAGG GTGGTTAGAAGAGCTAAAAAAACATCAACCAATATTGATTGATCCAATGTGTGGTTCTGGGACTATACTTATCGAAGCTG CTCTTATGGCAAAAAATATCGCTCCGGTGCTGCTTAATAAAGAATTTAAAATATTTAACTCAAAGTTTCATAATCAAGAG TTGTGGGATAATTTATTAGAAATAGCAAAAAACTCACAAAAAGTTACTAATGCAATTATTTGTGGGTTTGATATTGATAA TAATGTTTTGGATAAAGCACAGAGAAATATTTACCAAGCTGGTGTTGAAGATGTTGTAACTGTTAAACGCCAAGATATTC GTGACCTTGAAAATGAGTTTGAAAGTGAAGGCTTGATAGTTACAAATCCTCCATATGGTGAGCGATTATATGGTGATCAA CTTGATGAACTTTTGGATATTTTTAATGGCTTTGGTGATAGATTATCGCAAGATTTTTATGGCTGGAAAGTAGCTGTTTT GACAAGCTTTGCTGATTCAATCAAAGAGATGCAACTGCGTACGACTGAACGTAACAAATTTTATAATGGTGCTATTGAAA CTATCCTTTATCAGTTTAAGATAAATGAACATGCTAAATTTAAACATGAAACTCAGCTTGAGAAAAATATCCGTATAGCC GAAGCAAGTGCACAGAAGTCTGATGAACATATAGATTTTGCAAACAAGCTCAAAAAGAATCTCAAAAGTTTAAAGCCATG GCTCAAGCAAACAGGTCTCGAGTGTTATAGGTTATATGATGCAGATATTCCAACTTTTGCGGTTGCAGTTGATGTATATA GTGAGCATATTTTTTTACAAGAATATCGCGCCGATGCAACTATAGATCAAAATATTGCTAAACAAAGGTTCTATCAAGCT ATATATCAGATACATAAAACACTTGATATAAAGTATGAAAATATCCATACACGAGTCCGTCAACGTCAAAAAGGCAAAGA GCAGTATCAAAAAGAAAATGATAAAAATAAATTTCATATTATTAATGAATTTGATGCTAAGTTTTATGTCAATTTTGATG ATTATTTAGATACCGGTATATTCTTAGATCATCGCAAAATTAGGCAGCTAGTTGCAAAAGCTGCAAAAAACAAAACTTTA TTAAATCTATTTAGCTATACATGTACAGCAAGTGTTCATGCTGCTTTGAAAGGTGCAAAAACTACAAGTGTAGATATGTC TAATACTTATCTTGAATGGGGTAAGAATAATTTCACACTAAACAATATCGATGCTAAAAAACATAGTTTTATCCAAGCAG ATTGTATAAGTTGGCTAAAAACTAATAAAGACAAGTTTGATGTGATATTTTTAGATCCACCAACTTTCTCAAATTCAAAG CGTATGGATGATATTTTAGATATTCAAAGGGATCATGAATTGTTGATAAATTTAGCAATGGATTCTCTTAAGAAAGATGG GATACTTTATTTCTCAAACAATTATCGTCGCTTTAAAATGTCACCACAAATATTAGAAAAATTTAATTGCGAAAATATTG ATAAAATCTGTTTATCGCGTGATTTCTTATCTAATAAAAATATTCATAACTGTTGGGAAATTAAATATAAATAA
Upstream 100 bases:
>100_bases GGACTAAAGGAAAACAAAAAGATTAGCTTCTAATACTGATTGTTATTTATGTTAATTAATATATCATGTTAAGACATATT CTATAATTTTATATTTTCTC
Downstream 100 bases:
>100_bases AACTATCTCAGAATCTAGTATTTTAAAGTCTGTAATATTTTAGCTAAGCTAATCTATCTGTGATAAAATTTGCATAGCAA TAAAAAAATATATTTAATTA
Product: 23S rRNA m(2)G2445 methyltransferase
Products: NA
Alternate protein names: 23S rRNA m2G2445 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmL [H]
Number of amino acids: Translated: 717; Mature: 717
Protein sequence:
>717_residues MQKFTFFVSCAKGIELLLKDELERLGISSQEKLAGVEFEGSIKDAYKVCIYSYLASQVMLKVATDKVINQQDLYEFISSI NWMDYFAVDKTFKIIISGKHYDFNNTMFVSQKTKDAIVDQFRNVINQRPNIDTENPDNVIKLHLHKQFVNVFLCLNIDSL HKRSYRQFQGQAPLKESLAAAILIKAGWLEELKKHQPILIDPMCGSGTILIEAALMAKNIAPVLLNKEFKIFNSKFHNQE LWDNLLEIAKNSQKVTNAIICGFDIDNNVLDKAQRNIYQAGVEDVVTVKRQDIRDLENEFESEGLIVTNPPYGERLYGDQ LDELLDIFNGFGDRLSQDFYGWKVAVLTSFADSIKEMQLRTTERNKFYNGAIETILYQFKINEHAKFKHETQLEKNIRIA EASAQKSDEHIDFANKLKKNLKSLKPWLKQTGLECYRLYDADIPTFAVAVDVYSEHIFLQEYRADATIDQNIAKQRFYQA IYQIHKTLDIKYENIHTRVRQRQKGKEQYQKENDKNKFHIINEFDAKFYVNFDDYLDTGIFLDHRKIRQLVAKAAKNKTL LNLFSYTCTASVHAALKGAKTTSVDMSNTYLEWGKNNFTLNNIDAKKHSFIQADCISWLKTNKDKFDVIFLDPPTFSNSK RMDDILDIQRDHELLINLAMDSLKKDGILYFSNNYRRFKMSPQILEKFNCENIDKICLSRDFLSNKNIHNCWEIKYK
Sequences:
>Translated_717_residues MQKFTFFVSCAKGIELLLKDELERLGISSQEKLAGVEFEGSIKDAYKVCIYSYLASQVMLKVATDKVINQQDLYEFISSI NWMDYFAVDKTFKIIISGKHYDFNNTMFVSQKTKDAIVDQFRNVINQRPNIDTENPDNVIKLHLHKQFVNVFLCLNIDSL HKRSYRQFQGQAPLKESLAAAILIKAGWLEELKKHQPILIDPMCGSGTILIEAALMAKNIAPVLLNKEFKIFNSKFHNQE LWDNLLEIAKNSQKVTNAIICGFDIDNNVLDKAQRNIYQAGVEDVVTVKRQDIRDLENEFESEGLIVTNPPYGERLYGDQ LDELLDIFNGFGDRLSQDFYGWKVAVLTSFADSIKEMQLRTTERNKFYNGAIETILYQFKINEHAKFKHETQLEKNIRIA EASAQKSDEHIDFANKLKKNLKSLKPWLKQTGLECYRLYDADIPTFAVAVDVYSEHIFLQEYRADATIDQNIAKQRFYQA IYQIHKTLDIKYENIHTRVRQRQKGKEQYQKENDKNKFHIINEFDAKFYVNFDDYLDTGIFLDHRKIRQLVAKAAKNKTL LNLFSYTCTASVHAALKGAKTTSVDMSNTYLEWGKNNFTLNNIDAKKHSFIQADCISWLKTNKDKFDVIFLDPPTFSNSK RMDDILDIQRDHELLINLAMDSLKKDGILYFSNNYRRFKMSPQILEKFNCENIDKICLSRDFLSNKNIHNCWEIKYK >Mature_717_residues MQKFTFFVSCAKGIELLLKDELERLGISSQEKLAGVEFEGSIKDAYKVCIYSYLASQVMLKVATDKVINQQDLYEFISSI NWMDYFAVDKTFKIIISGKHYDFNNTMFVSQKTKDAIVDQFRNVINQRPNIDTENPDNVIKLHLHKQFVNVFLCLNIDSL HKRSYRQFQGQAPLKESLAAAILIKAGWLEELKKHQPILIDPMCGSGTILIEAALMAKNIAPVLLNKEFKIFNSKFHNQE LWDNLLEIAKNSQKVTNAIICGFDIDNNVLDKAQRNIYQAGVEDVVTVKRQDIRDLENEFESEGLIVTNPPYGERLYGDQ LDELLDIFNGFGDRLSQDFYGWKVAVLTSFADSIKEMQLRTTERNKFYNGAIETILYQFKINEHAKFKHETQLEKNIRIA EASAQKSDEHIDFANKLKKNLKSLKPWLKQTGLECYRLYDADIPTFAVAVDVYSEHIFLQEYRADATIDQNIAKQRFYQA IYQIHKTLDIKYENIHTRVRQRQKGKEQYQKENDKNKFHIINEFDAKFYVNFDDYLDTGIFLDHRKIRQLVAKAAKNKTL LNLFSYTCTASVHAALKGAKTTSVDMSNTYLEWGKNNFTLNNIDAKKHSFIQADCISWLKTNKDKFDVIFLDPPTFSNSK RMDDILDIQRDHELLINLAMDSLKKDGILYFSNNYRRFKMSPQILEKFNCENIDKICLSRDFLSNKNIHNCWEIKYK
Specific function: Specifically methylates the guanosine in position 2445 (m2G2445) of 23S rRNA [H]
COG id: COG1092
COG function: function code R; Predicted SAM-dependent methyltransferases
Gene ontology:
Cell location: Cytoplasm (Potential) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 THUMP domain [H]
Homologues:
Organism=Escherichia coli, GI1787181, Length=724, Percent_Identity=39.3646408839779, Blast_Score=523, Evalue=1e-149, Organism=Escherichia coli, GI145693111, Length=312, Percent_Identity=27.5641025641026, Blast_Score=89, Evalue=1e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002052 - InterPro: IPR000241 - InterPro: IPR017244 - InterPro: IPR019614 - InterPro: IPR004114 [H]
Pfam domain/function: PF10672 Methyltrans_SAM; PF02926 THUMP; PF01170 UPF0020 [H]
EC number: =2.1.1.173 [H]
Molecular weight: Translated: 83482; Mature: 83482
Theoretical pI: Translated: 7.91; Mature: 7.91
Prosite motif: PS51165 THUMP ; PS00092 N6_MTASE ; PS01261 UPF0020
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQKFTFFVSCAKGIELLLKDELERLGISSQEKLAGVEFEGSIKDAYKVCIYSYLASQVML CCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH KVATDKVINQQDLYEFISSINWMDYFAVDKTFKIIISGKHYDFNNTMFVSQKTKDAIVDQ HHHHHHHCCHHHHHHHHHHCCCHHHEECCCEEEEEEECCEECCCCEEEEECCHHHHHHHH FRNVINQRPNIDTENPDNVIKLHLHKQFVNVFLCLNIDSLHKRSYRQFQGQAPLKESLAA HHHHHHCCCCCCCCCCCCEEEEEEHHHHHHEEEEECCHHHHHHHHHHHCCCCCHHHHHHH AILIKAGWLEELKKHQPILIDPMCGSGTILIEAALMAKNIAPVLLNKEFKIFNSKFHNQE HHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEHHHHHCCCCHHHCCCCHHHHHHHCCCHH LWDNLLEIAKNSQKVTNAIICGFDIDNNVLDKAQRNIYQAGVEDVVTVKRQDIRDLENEF HHHHHHHHHHCCHHHCEEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH ESEGLIVTNPPYGERLYGDQLDELLDIFNGFGDRLSQDFYGWKVAVLTSFADSIKEMQLR CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH TTERNKFYNGAIETILYQFKINEHAKFKHETQLEKNIRIAEASAQKSDEHIDFANKLKKN HHHCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHH LKSLKPWLKQTGLECYRLYDADIPTFAVAVDVYSEHIFLQEYRADATIDQNIAKQRFYQA HHHHHHHHHHCCCCEEEEECCCCCHHEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH IYQIHKTLDIKYENIHTRVRQRQKGKEQYQKENDKNKFHIINEFDAKFYVNFDDYLDTGI HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEHHHHCCCE FLDHRKIRQLVAKAAKNKTLLNLFSYTCTASVHAALKGAKTTSVDMSNTYLEWGKNNFTL EECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCCCCEE NNIDAKKHSFIQADCISWLKTNKDKFDVIFLDPPTFSNSKRMDDILDIQRDHELLINLAM ECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH DSLKKDGILYFSNNYRRFKMSPQILEKFNCENIDKICLSRDFLSNKNIHNCWEIKYK HHHCCCCEEEEECCCEEEECCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEC >Mature Secondary Structure MQKFTFFVSCAKGIELLLKDELERLGISSQEKLAGVEFEGSIKDAYKVCIYSYLASQVML CCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH KVATDKVINQQDLYEFISSINWMDYFAVDKTFKIIISGKHYDFNNTMFVSQKTKDAIVDQ HHHHHHHCCHHHHHHHHHHCCCHHHEECCCEEEEEEECCEECCCCEEEEECCHHHHHHHH FRNVINQRPNIDTENPDNVIKLHLHKQFVNVFLCLNIDSLHKRSYRQFQGQAPLKESLAA HHHHHHCCCCCCCCCCCCEEEEEEHHHHHHEEEEECCHHHHHHHHHHHCCCCCHHHHHHH AILIKAGWLEELKKHQPILIDPMCGSGTILIEAALMAKNIAPVLLNKEFKIFNSKFHNQE HHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEHHHHHCCCCHHHCCCCHHHHHHHCCCHH LWDNLLEIAKNSQKVTNAIICGFDIDNNVLDKAQRNIYQAGVEDVVTVKRQDIRDLENEF HHHHHHHHHHCCHHHCEEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH ESEGLIVTNPPYGERLYGDQLDELLDIFNGFGDRLSQDFYGWKVAVLTSFADSIKEMQLR CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH TTERNKFYNGAIETILYQFKINEHAKFKHETQLEKNIRIAEASAQKSDEHIDFANKLKKN HHHCCHHHHHHHHHHEEEEEECCCCCCCHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHH LKSLKPWLKQTGLECYRLYDADIPTFAVAVDVYSEHIFLQEYRADATIDQNIAKQRFYQA HHHHHHHHHHCCCCEEEEECCCCCHHEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH IYQIHKTLDIKYENIHTRVRQRQKGKEQYQKENDKNKFHIINEFDAKFYVNFDDYLDTGI HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEHHHHCCCE FLDHRKIRQLVAKAAKNKTLLNLFSYTCTASVHAALKGAKTTSVDMSNTYLEWGKNNFTL EECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCCCCEE NNIDAKKHSFIQADCISWLKTNKDKFDVIFLDPPTFSNSKRMDDILDIQRDHELLINLAM ECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH DSLKKDGILYFSNNYRRFKMSPQILEKFNCENIDKICLSRDFLSNKNIHNCWEIKYK HHHCCCCEEEEECCCEEEECCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA