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The map label for this gene is gluP [H]

Identifier: 89256587

GI number: 89256587

Start: 1218136

End: 1219395

Strand: Reverse

Name: gluP [H]

Synonym: FTL_1278

Alternate gene names: 89256587

Gene position: 1219395-1218136 (Counterclockwise)

Preceding gene: 89256592

Following gene: 89256586

Centisome position: 64.31

GC content: 30.32

Gene sequence:

>1260_bases
ATGAAAAAAAATTATTTAATAGTATCTGTGGTGATGATTGGCTTTTTTGCTGTATCATTTGTAACTAATATTTTAGGATC
TATAATTCCAGATGCAACTAACGATCTACATTTGACACTTTCGCAAGCTGGAGTTTTACCTTTTGCATTTTTTATAGCTT
ATATTATTTCAATTCCTGCAGGCTATGCGCTAGAGAAATATGGATCCAAAAAGATGATCTTATTTGCTTTTTTATTGGGC
TCTCTGGGTTCAATTTTATTCTGTCTAAAAGTTAGCTATCTTACTTATATTGTAAGTTTATTTACAGTTGGTACAGCTGC
TGCGATACTACAAGTAGCTTTTTGGCCTTTATTAAGAGTTGCTGGTGGAGAGGAGAATTACTCATTTTTCTCTGTATTAC
AGAAGGTATTTTTTGGTGGAGCATCATTTGTTAGTCCATTTGTACTATCTTATTTAGTTATGAATCTTCCATATTCTGGA
GAAAGTAATTATTTTTTATTATTTTTTAATAAGCTAACAGGAACAAACTTTAGTTGGGTTGCTATTTATTGGTTTAATGC
CATTGTAATGTTTTTGTTAGTGGTATTTATCAGTTTAATTAAGTTTCCAAAAGTTGAGTTAAAGGAAGATGAGAAATTAG
AGGGTTTTGCTACTGTATTACATCTTCTAAAAAATAAAGTCGTAATAATATATTTCTTAGCAATTTTTGCTTATGTTGGT
CAAGAGCAAGGAATCAGTGTTTGGATTTCTAAATTCTTGAGTGACTATCATGGCTTTAATACCGAAACTGTAGGCAATAC
TACAGTAGCATTATTCTGGATCATGCAATGTGTTGGCGGTATTTTAGGGATAGTTTTATTGAAGCTATATAATGTCAAAA
ATATTTTGAAAGTATTTCTAATTTTACAACTAATATCATTGTCTCTAGCATTGTTTGGATCAGCTACTATGGCTTTGATA
TTTTTCCCTGTTTGTGGTTTCTTAACATCAATAATGTATGGAGGAGTTTTCTCATTGGGAATGAATTCTTTAAAATCACA
TCATGGAACAGTATCAGGAATATTTTGTACTGGGATAATTGGTGGTGCTATAGTGCCATTAGTGGTTGGTAATATTGGAG
ATATCTTAGGCTTAAGAATAGCAATGTGTTTTGTATATCTAACTATAGTATATATTTTATATGTAGCTATAACAGCTAAG
CCATTAATTGATAATAAAACTATAAAGCTGACAGAATTATTTAAAAATAAGTTGAAGTGA

Upstream 100 bases:

>100_bases
ATATTTGATAAAGATATGCTTTTGTACAAACTAGTTACTTGATTAAAAGTAATAATTTAAAGTTAATGGATAGACTTAGA
AATTTTTTGAGGCAAGTTTT

Downstream 100 bases:

>100_bases
TATGAGTAAAGAAATTCAAATTAAGAATAGAACTGTGGTTGGTGTTGATATCGGTGGCACTAAAGTGAATGCTGGTAGGG
TATGTGGAGAAAATCTATTA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKKNYLIVSVVMIGFFAVSFVTNILGSIIPDATNDLHLTLSQAGVLPFAFFIAYIISIPAGYALEKYGSKKMILFAFLLG
SLGSILFCLKVSYLTYIVSLFTVGTAAAILQVAFWPLLRVAGGEENYSFFSVLQKVFFGGASFVSPFVLSYLVMNLPYSG
ESNYFLLFFNKLTGTNFSWVAIYWFNAIVMFLLVVFISLIKFPKVELKEDEKLEGFATVLHLLKNKVVIIYFLAIFAYVG
QEQGISVWISKFLSDYHGFNTETVGNTTVALFWIMQCVGGILGIVLLKLYNVKNILKVFLILQLISLSLALFGSATMALI
FFPVCGFLTSIMYGGVFSLGMNSLKSHHGTVSGIFCTGIIGGAIVPLVVGNIGDILGLRIAMCFVYLTIVYILYVAITAK
PLIDNKTIKLTELFKNKLK

Sequences:

>Translated_419_residues
MKKNYLIVSVVMIGFFAVSFVTNILGSIIPDATNDLHLTLSQAGVLPFAFFIAYIISIPAGYALEKYGSKKMILFAFLLG
SLGSILFCLKVSYLTYIVSLFTVGTAAAILQVAFWPLLRVAGGEENYSFFSVLQKVFFGGASFVSPFVLSYLVMNLPYSG
ESNYFLLFFNKLTGTNFSWVAIYWFNAIVMFLLVVFISLIKFPKVELKEDEKLEGFATVLHLLKNKVVIIYFLAIFAYVG
QEQGISVWISKFLSDYHGFNTETVGNTTVALFWIMQCVGGILGIVLLKLYNVKNILKVFLILQLISLSLALFGSATMALI
FFPVCGFLTSIMYGGVFSLGMNSLKSHHGTVSGIFCTGIIGGAIVPLVVGNIGDILGLRIAMCFVYLTIVYILYVAITAK
PLIDNKTIKLTELFKNKLK
>Mature_419_residues
MKKNYLIVSVVMIGFFAVSFVTNILGSIIPDATNDLHLTLSQAGVLPFAFFIAYIISIPAGYALEKYGSKKMILFAFLLG
SLGSILFCLKVSYLTYIVSLFTVGTAAAILQVAFWPLLRVAGGEENYSFFSVLQKVFFGGASFVSPFVLSYLVMNLPYSG
ESNYFLLFFNKLTGTNFSWVAIYWFNAIVMFLLVVFISLIKFPKVELKEDEKLEGFATVLHLLKNKVVIIYFLAIFAYVG
QEQGISVWISKFLSDYHGFNTETVGNTTVALFWIMQCVGGILGIVLLKLYNVKNILKVFLILQLISLSLALFGSATMALI
FFPVCGFLTSIMYGGVFSLGMNSLKSHHGTVSGIFCTGIIGGAIVPLVVGNIGDILGLRIAMCFVYLTIVYILYVAITAK
PLIDNKTIKLTELFKNKLK

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=409, Percent_Identity=25.9168704156479, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46258; Mature: 46258

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNYLIVSVVMIGFFAVSFVTNILGSIIPDATNDLHLTLSQAGVLPFAFFIAYIISIPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHCCHHHHHHHHHHHHHCCC
GYALEKYGSKKMILFAFLLGSLGSILFCLKVSYLTYIVSLFTVGTAAAILQVAFWPLLRV
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGGEENYSFFSVLQKVFFGGASFVSPFVLSYLVMNLPYSGESNYFLLFFNKLTGTNFSWV
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHH
AIYWFNAIVMFLLVVFISLIKFPKVELKEDEKLEGFATVLHLLKNKVVIIYFLAIFAYVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
QEQGISVWISKFLSDYHGFNTETVGNTTVALFWIMQCVGGILGIVLLKLYNVKNILKVFL
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILQLISLSLALFGSATMALIFFPVCGFLTSIMYGGVFSLGMNSLKSHHGTVSGIFCTGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GGAIVPLVVGNIGDILGLRIAMCFVYLTIVYILYVAITAKPLIDNKTIKLTELFKNKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKNYLIVSVVMIGFFAVSFVTNILGSIIPDATNDLHLTLSQAGVLPFAFFIAYIISIPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHCCHHHHHHHHHHHHHCCC
GYALEKYGSKKMILFAFLLGSLGSILFCLKVSYLTYIVSLFTVGTAAAILQVAFWPLLRV
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGGEENYSFFSVLQKVFFGGASFVSPFVLSYLVMNLPYSGESNYFLLFFNKLTGTNFSWV
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHH
AIYWFNAIVMFLLVVFISLIKFPKVELKEDEKLEGFATVLHLLKNKVVIIYFLAIFAYVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
QEQGISVWISKFLSDYHGFNTETVGNTTVALFWIMQCVGGILGIVLLKLYNVKNILKVFL
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILQLISLSLALFGSATMALIFFPVCGFLTSIMYGGVFSLGMNSLKSHHGTVSGIFCTGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GGAIVPLVVGNIGDILGLRIAMCFVYLTIVYILYVAITAKPLIDNKTIKLTELFKNKLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]