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The map label for this gene is tas [H]

Identifier: 89256572

GI number: 89256572

Start: 1201268

End: 1202272

Strand: Direct

Name: tas [H]

Synonym: FTL_1258

Alternate gene names: 89256572

Gene position: 1201268-1202272 (Clockwise)

Preceding gene: 89256571

Following gene: 89256576

Centisome position: 63.36

GC content: 36.12

Gene sequence:

>1005_bases
ATGACATGGGGACGTCAAAATACTCAAGCTGAAGGTTTTGAACAAATGGATTATGCTCTTGCTCAAGGTATCAACTTTGG
GGATACAGCAGAAATGTATGCGATTCCCCCTACTGCTAAGACTTATGGTAAAACTGAAGAGATAATCGGTAACTGGTTTA
AAACAAGGCAAAAACGTAGTGATGTTATGTTAGCAACTAAATTCTCGCCGATGACATGGGCTAGAAATGAACAAAACCCT
ATCACAAATAAGGTAAATATTATCGATGCCGTAGATAATAGTCTAAAACGCCTAAAGACTGATTATATCGATTTATACCA
ATTCCACTGGCCAACAAATAGACCTCACTATCATTTTGGTAATTGGTGGGATTTTGAACCTCTAGTAGGGCAACAAAATA
AACAACGTATAGTTGATAATATCCATGAAATTCTAGTTACTTGCGATGAGTTAGTTAAGGCTGGAAAGATTAGACACATA
GGTCTGTCAAATGACTCTGCATGGGGAATTAATCAATTTATCAAACTTGCAGAAAAACATAAACTACCACGTCTAGCAAG
TATTCAGCATGAATATAATCTTAATCGTCGTAGAGACGAAACAGATATTATGGAGACTTGTGCTCTTGAAGAAATATCAT
ATCTTGCATGGTCACCACTTGAGCAAGGAGTGCTAACAGGCAAATATCGTAATGGTGCTCGCCCTGCTGGCACTAGAATG
TCTGCTGAAATTCTAGATGGCCAAGAAGATCGCTATGCTTTTAGATTTGCTACCAACGATGATGCTGTGACAGCGTATAT
TAATATTGCAAAAAAACATAACCTTGATATTTGTCAAATGGCTATCGCTTTTACGATTAGAAAAGCATATATGAGTTGTA
GTATAATTGGTGCTACATCTATGGAGCAGCTAAAAACAAATATTGAAGCGATTAATTTAAACCTATATGATGAGGTTTTA
GCTGATATTGAAAAAGTTAGAAGAAAATATCCAATACCGTTTTAA

Upstream 100 bases:

>100_bases
TAATTTTAACTGTTATATTCAGTTATTTGCTATAATCTTGTTATATTAATTTTTTAGAAGTAATTATGAAATATACTAAA
TTAGGTAAAACCTTGGTACG

Downstream 100 bases:

>100_bases
CAATAGATTTAAAACATTGTCGAAAAAAATCCTTCTAATCTTAATATGGTTAAGTGCAGTAGCATTTTATATGTATACTC
GTATGATAAATACTTCACTT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTWGRQNTQAEGFEQMDYALAQGINFGDTAEMYAIPPTAKTYGKTEEIIGNWFKTRQKRSDVMLATKFSPMTWARNEQNP
ITNKVNIIDAVDNSLKRLKTDYIDLYQFHWPTNRPHYHFGNWWDFEPLVGQQNKQRIVDNIHEILVTCDELVKAGKIRHI
GLSNDSAWGINQFIKLAEKHKLPRLASIQHEYNLNRRRDETDIMETCALEEISYLAWSPLEQGVLTGKYRNGARPAGTRM
SAEILDGQEDRYAFRFATNDDAVTAYINIAKKHNLDICQMAIAFTIRKAYMSCSIIGATSMEQLKTNIEAINLNLYDEVL
ADIEKVRRKYPIPF

Sequences:

>Translated_334_residues
MTWGRQNTQAEGFEQMDYALAQGINFGDTAEMYAIPPTAKTYGKTEEIIGNWFKTRQKRSDVMLATKFSPMTWARNEQNP
ITNKVNIIDAVDNSLKRLKTDYIDLYQFHWPTNRPHYHFGNWWDFEPLVGQQNKQRIVDNIHEILVTCDELVKAGKIRHI
GLSNDSAWGINQFIKLAEKHKLPRLASIQHEYNLNRRRDETDIMETCALEEISYLAWSPLEQGVLTGKYRNGARPAGTRM
SAEILDGQEDRYAFRFATNDDAVTAYINIAKKHNLDICQMAIAFTIRKAYMSCSIIGATSMEQLKTNIEAINLNLYDEVL
ADIEKVRRKYPIPF
>Mature_333_residues
TWGRQNTQAEGFEQMDYALAQGINFGDTAEMYAIPPTAKTYGKTEEIIGNWFKTRQKRSDVMLATKFSPMTWARNEQNPI
TNKVNIIDAVDNSLKRLKTDYIDLYQFHWPTNRPHYHFGNWWDFEPLVGQQNKQRIVDNIHEILVTCDELVKAGKIRHIG
LSNDSAWGINQFIKLAEKHKLPRLASIQHEYNLNRRRDETDIMETCALEEISYLAWSPLEQGVLTGKYRNGARPAGTRMS
AEILDGQEDRYAFRFATNDDAVTAYINIAKKHNLDICQMAIAFTIRKAYMSCSIIGATSMEQLKTNIEAINLNLYDEVLA
DIEKVRRKYPIPF

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=337, Percent_Identity=24.9258160237389, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI27436964, Length=337, Percent_Identity=24.9258160237389, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436966, Length=337, Percent_Identity=24.9258160237389, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436969, Length=336, Percent_Identity=25.297619047619, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4504825, Length=336, Percent_Identity=25.297619047619, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=42.6900584795322, Blast_Score=267, Evalue=8e-73,
Organism=Escherichia coli, GI87081735, Length=317, Percent_Identity=28.7066246056782, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1788070, Length=307, Percent_Identity=28.3387622149837, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789375, Length=309, Percent_Identity=25.5663430420712, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=26.625386996904, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=23.8670694864048, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=335, Percent_Identity=23.8805970149254, Blast_Score=82, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=334, Percent_Identity=23.6526946107784, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322615, Length=291, Percent_Identity=22.680412371134, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38566; Mature: 38435

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWGRQNTQAEGFEQMDYALAQGINFGDTAEMYAIPPTAKTYGKTEEIIGNWFKTRQKRS
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCCHHHHHHHHHHHHHHHC
DVMLATKFSPMTWARNEQNPITNKVNIIDAVDNSLKRLKTDYIDLYQFHWPTNRPHYHFG
CEEEEEECCCCEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
NWWDFEPLVGQQNKQRIVDNIHEILVTCDELVKAGKIRHIGLSNDSAWGINQFIKLAEKH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
KLPRLASIQHEYNLNRRRDETDIMETCALEEISYLAWSPLEQGVLTGKYRNGARPAGTRM
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCEECCCCCCCCCCCCCC
SAEILDGQEDRYAFRFATNDDAVTAYINIAKKHNLDICQMAIAFTIRKAYMSCSIIGATS
CHHHHCCCCCCEEEEEECCCCEEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHEEEECCCC
MEQLKTNIEAINLNLYDEVLADIEKVRRKYPIPF
HHHHHHCHHEEEECHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TWGRQNTQAEGFEQMDYALAQGINFGDTAEMYAIPPTAKTYGKTEEIIGNWFKTRQKRS
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCCHHHHHHHHHHHHHHHC
DVMLATKFSPMTWARNEQNPITNKVNIIDAVDNSLKRLKTDYIDLYQFHWPTNRPHYHFG
CEEEEEECCCCEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
NWWDFEPLVGQQNKQRIVDNIHEILVTCDELVKAGKIRHIGLSNDSAWGINQFIKLAEKH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHH
KLPRLASIQHEYNLNRRRDETDIMETCALEEISYLAWSPLEQGVLTGKYRNGARPAGTRM
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCEECCCCCCCCCCCCCC
SAEILDGQEDRYAFRFATNDDAVTAYINIAKKHNLDICQMAIAFTIRKAYMSCSIIGATS
CHHHHCCCCCCEEEEEECCCCEEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHEEEECCCC
MEQLKTNIEAINLNLYDEVLADIEKVRRKYPIPF
HHHHHHCHHEEEECHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]